Clinical trials: Labour
Failed Induction of Labor
Vaginal Estradiol Pretreatment in Labour Induction With Misoprostol
To assess the effect of vaginal estradiol pretreatment before vaginal misoprostol on labor induction.
- Trial name
- NCT02485821
- Testing
- Estradiol, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor Pain, Analgesia, Epidural
A Study on the Effect of Position on Walking Labour Epidural Efficacy
This study is being done to better understand how patient positioning can affect pain relief after an epidural. In addition to pain, the investigators will assess how position affects epidural spread, and its effects on maternal…
- Trial name
- NCT04469101
- Testing
- Lumbar Epidural
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Failed Labor
Prediction of Delivery With Transperineal Ultrasound in Women With Prolonged Labour. Multicentre Study
Objectives 1. To assess if head-perineum distance and angle of progression measured with transperineal ultrasound by the obstetrician on call can predict delivery mode in primiparous women with prolonged first stage of labour. 2.
- Trial name
- NCT01610453
- Testing
- ultrasound examination
- Where
- 6 sites in Denmark, Norway and 2 more
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Labor; Prolonged, Second Stage, Delivery Problem
Maternal Position's Effect on Labor Progression in Occiput Posterior Deliveries
This is a randomized controlled experimental study to determine the effect of maternal position on the progression of labour in deliveries in which the foetus is in the occiput posterior position.
- Trial name
- NCT06928038
- Testing
- Positioned group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Caesarean Sections, Augmentation With Oxytocin
The Labour Progression Study, a Cluster Randomised Trial on Labour Progression for First Time Mothers
The purpose of this study is to evaluate if the rate of emergency caesarean section can be reduced if adhering to a dynamic labour progression curve compared to a static progression curve for first time mothers without…
- Conditions
- Caesarean Sections, Augmentation With Oxytocin, Labour Dystocia
- Trial name
- LAPS (NCT02221427)
- Testing
- Dynamic progression curve, Static labour progression curve (F)
- Where
- Norway
- Volunteers
- 6,582 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Labor Pain
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction.
- Trial name
- NCT06572241
- Testing
- Intrathecal morphine
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Obstetric Labor, Premature
Impact of Threatened Preterm Labour in Fetal Cardiovascular and Metabolic Programming (SHs)
The goal of this observational study is to learn about cardiac function and remodelling and metabolomic profiles in fetuses and infants who were exposed to a threatened preterm labor (TPL) during pregnancy.
- Trial name
- SHs (NCT05670665)
- Testing
- Threatened preterm labor
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Uterine Contraction, Pregnancy
Comparative Study of the Propagation of Uterine Electrical Activity (EHG) in Pregnant Women During Pregnancy and During Labour
The original aspect of the methodology proposed for this study concerns the use of as many as 16 electrodes to study the propagation and coordination (or synchronization) of uterine contraction.
- Conditions
- Uterine Contraction, Pregnancy, Delivery, Obstetric
- Trial name
- PropEHG (NCT02814344)
- Testing
- Electrohysterography
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Labor Pain
Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
The study aims to investigate the effects of a combination of Lamaze breathing exercises and backside massage on the labor experiences of primigravidae in Pakistan.
- Trial name
- NCT06304311
- Testing
- Routine Obstetrics care & Lamaze breathing techniques and backside massage, Routine obstetrics care
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Labor Pain
Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia
This study aims to establish if programmed intermittent epidural bolus combined to patient controlled analgesia in labour analgesia will lower the hourly bupivacaine consumption when compared to continuous infusion combined with…
- Trial name
- NCT03730753
- Testing
- Programmed intermittent epidural bolus, Continuous infusion
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Labour Analgesia and Neonate Activity
Labour Analgesia and Movement in Babies
This study aims to measure movements in babies after they are born using an actigraph, a wristwatch-sized device worn on the ankle, which works similarly to the device used by runners to count the number of steps they have taken.
- Trial name
- LAMB (NCT01280084)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Labor Pain
The Effect of Continuous Midwifery-led Care in Birth Management
Caesarean section is an emergency procedure necessary to prevent harm or death to the mother or newborn. Worldwide, caesarean section rates are steadily increasing.
- Trial name
- NCT06660615
- Testing
- MIDWIFE-LED CARE
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Induction of Labor Affected Fetus / Newborn, Prostaglandins Causing Adverse Effects in Therapeutic Use
Induction of Labor in Term Pregnancies With Unfavourable Cervix
This is a prospective randomized trial comparing two prostaglandin E2 (dinoprostone) agents used for labor induction in pregnant women with term pregnancies and unfavorable cervix.
- Trial name
- RAND (NCT04280874)
- Testing
- Dinoprostone 0.5 MG, Dinoprostone 2 MG/2.5 ML Vaginal Gel/Jelly
- Where
- Croatia
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Merkur
Pregnancy
Impact of Prenatal Yoga Practice on Birth Outcome
Yoga is a body-mind practice that encompasses a system of postures (asana), stretching exercises combined with breathing (pranayama) and meditation (dharana).
- Trial name
- NCT03941041
- Testing
- Prenatal Yoga Course
- Where
- Slovenia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Labour
Effects of Reiki Intervention During Labor on Pain, Fear, and Birth Experience
Childbirth is an important and often stressful experience for many women, and labor pain is common among women. While labor pain is a natural part of the birth process, its severity and management can have a significant impact on…
- Trial name
- NCT06700473
- Testing
- reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain
Preventive Analgesia in Multiparas Undergoing Induction of Labour
Our study is about providing a better birthing experience by placing and initiating epidural for labour pain before the contractions start.
- Trial name
- NCT00465231
- Testing
- bupivacaine, fentanyl, preservative free saline
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Induced; Birth, Cervical Dilatation
Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
The goal of this clinical trial] is to compare the outcomes between induction to labour at home versus hospitalized. The main questions it aims to answer are: Can the induction to labour at home with cervical rippening ballon…
- Conditions
- Induced; Birth, Cervical Dilatation, Live Birth
- Trial name
- INDOBAMHOS (NCT06053073)
- Testing
- Cervical rippening at home, Cervical rippening in the hospital
- Where
- Spain
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Labor Pain
Dexmedetomidine for Intermittent Epidural Boluses Versus Continuous Epidural Infusion for Labour Epidural Analgesia
The aim of this study is to compare two modes of labour epidural analgesia: programmed intermittent epidural boluses (PIEB) versus continuous epidural infusion (CEI), with patient controlled epidural analgesia (PCEA), using…
- Trial name
- NCT05781854
- Testing
- Epidural analgesia with bupivacaine and dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University