Clinical trials: Labour
Induced; Birth
Outcome of Concurrent Versus Sequential Method of Induction of Labour in Term Pregnancy
This randomized controlled trial will compare two methods of induction of labour in women with term pregnancy: concurrent use of a Foley catheter and PGE2 vaginal pessary versus sequential use of the two methods.
- Trial name
- NCT07821099
- Testing
- Foley Catheter, PGE2 Vaginal Pessary
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Khyber Medical University Peshawar
Preterm Labor With Preterm Delivery
Comparative Study Between Nicorandil and Nifedipine for the Treatment of Preterm Labour
Nicorandil (potassium channel activator) is claimed to be as effective as Nifedipine (calcium channel blocker) for tocolysis in preterm labour aim of the study: To assess the efficacy of Nicorandil compared with Nifedipine as a…
- Trial name
- NCT04846621
- Testing
- Potassium Channel Opener, Calcium channel blocker
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preterm Labor, Premature Birth
Low Dose Aspirin vs Placebo in Prevention of Recurrent Spontaneous Preterm Labour
Preterm birth-defined as delivery before 37 weeks of gestation-is a leading cause of neonatal morbidity and mortality worldwide, particularly in resource-limited settings.
- Trial name
- NCT07745595
- Testing
- Low-dose Aspirin
- Volunteers
- 162 people
- Sponsor
- University of Health Sciences Lahore
Obstetric Labour, Premature
This Study Will Investigate the Effect of Single Oral Doses of Retosiban on Cardiac Repolarization, With Moxifloxacin as a Positive Control in Healthy Volunteers.
This will be a randomized, placebo-controlled, single, oral dose, four-way Williams crossover study design in healthy male and female subjects.
- Trial name
- NCT01702376
- Testing
- Retosiban 100 mg, Retosiban 800 mg, Moxifloxacin 400 mg
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Preterm Labor
Nifedipine Pharmacokinetics and Pharmacodynamics When Used as a Tocolytic in Acute Threatened Preterm Labour
Preterm birth is the leading cause of perinatal mortality and morbidity. According to WHO, 15 million children are born prematurely (gestational age < 37 weeks) in the world each year while 7% of them die because of complications…
- Trial name
- NCT02068404
- Testing
- Nifedipine
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Chantal Csajka
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pregnancy Related, Induction of Labor Affected Fetus / Newborn
Outpatient Induction of Labour Using Intracervical Foley Catheter
Prospective quasi-experimental study between a study population who will receive outpatient induction of labour using intracervical Foley catheter, followed by the inpatient induction using intravaginal prostaglandin and a…
- Trial name
- OFC (NCT05622968)
- Testing
- Foley catheter, Intravaginal prostaglandin E2
- Where
- Malaysia
- Volunteers
- 88 people
- Sponsor
- Hospital Kemaman
Labor Pain
The Effect of Sacral Massage on Labor
Nonpharmacologic pain control methods, which are increasingly becoming widespread in coping with the labour pain, are the methods that allow women to completely relax without using any medication and direct them to perceive the…
- Trial name
- NCT03755284
- Testing
- Sacral Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semra Çevik, phD
Slow Labour Progress
Labour Augmentation by Means of Oxytocin - Obstetric Outcome and Women's Experiences
Slow labour progress is common in nulliparous women and is associated with childbirth complications and negative birth experiences. Oxytocin augmentation is widely used to treat slow labour despite associated risks for the fetus.
- Trial name
- NCT01263158
- Testing
- Expectancy of standard oxytocin treatment
- Where
- Sweden
- Volunteers
- 2,072 people
- Sponsor
- Göteborg University
Vaginal Delivery
Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women
A case control trial Patients who meet the inclusion criteria were asked to participate in the study and a written consent was obtained from each patient after explaining thoroughly the nature and the scope of the study.
- Trial name
- NCT03055390
- Testing
- hyoscine butylbromide
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Membrane Stripping, Patient Experience
Membrane Sweeping as an Induction Method and Maternal Experience: a Phenomenological Qualitative Study
This qualitative phenomenological study explores women's experiences with membrane sweeping, a common mechanical method of labor induction.
- Conditions
- Membrane Stripping, Patient Experience, Labour, Induced, Phenomenology
- Trial name
- Sweep (NCT07154862)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Section
Misoprostol Versus Active Management of Labour in CS
Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .
- Trial name
- NCT03390010
- Testing
- Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine, Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Labour Analgesia
Spinal Analgesia in Labour Pain
To evaluate the efficacy and safety of dexmedetomidine as an adjuvant to bupivacain and fentanyl in spinal Analgesia to decreases pain during normal labour
- Trial name
- NCT07332130
- Testing
- injecting dexmedetomidine, injecting mixture of bupivacaine fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University Hospital
Labor Pain
Response Patterns to the Electric Stimulation of Epidural Catheters in Term Pregnant Women
Lumbar epidural analgesia is commonly used for labor pain relief due to its effectiveness and safety. Despite its very high success rate, the epidural technique remains a rather blind technique and failures continue to occur.
- Trial name
- NCT02274467
- Testing
- Trans-catheter electric stimulation test
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Induction
Observatory on Artificial Labour-induction Methods and Measuring Immediate Postpartum Maternal Satisfaction
Our hypothesis is that there is one sequence of labour-induction that leads to a better experience of childbirth than others. This is based on the following underlying theories : Maternal satisfaction depends on the number of…
- Trial name
- SATISFACC (NCT04075630)
- Where
- 2 sites in France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Labor Pain, Obstetric Pain
Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia
Epidural Analgesia remains the most effective form of pain relief in labour. After initiating epidural analgesia, there are many epidural drug regimens that can be employed to maintain analgesia for the duration of labour using…
- Conditions
- Labor Pain, Obstetric Pain, Analgesia
- Trial name
- PIEB (NCT06266767)
- Testing
- Levobupivacaine and Fentanyl
- Where
- Qatar
- Volunteers
- 136 people
- Sponsor
- Hamad Medical Corporation
Prolonged Labor
Amniotomy and Oxytocin for Augmentation of Labour
Prolonged labour is a cause of maternal mortality and morbidity and perinatal mortality and morbidity. Prolonged labour is most often defined as onset of regular , rhythmical painful contractions accompanied by cervical…
- Trial name
- AOAL (NCT02318121)
- Testing
- Amniotomy first, Oxytocin first, Amniotomy and oxytocin
- Volunteers
- 150 people
- Sponsor
- Assiut University
Labor Pain, Analgesia
Sacral Spread of Sensory Block After Dural Puncture Epidural Technique Compared With Epidural for Labour Analgesia
Neuraxial labor analgesia is a very widely used technique for labor pain relief with a high efficacy and safety. EA (Epidural analgesia) can guarantee a proper control of pain in 95-100% of cases in the first stage of labor, but…
- Trial name
- NCT05217134
- Testing
- DPEA
- Where
- 2 sites in Italy
- Volunteers
- 108 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labour Onset
Investigating the Physiology of Labour and Labour Onset Through Longitudinal Measurements Performed With a Wearable Sensor
The purpose of the study is to collect data to support the development and validation of a machine learning model for the automatic detection, prediction and monitoring of labour, through the use of a wearable sensor (Bloomlife…
- Trial name
- NCT03982654
- Testing
- Bloomlife
- Where
- 2 sites in Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Bloom Technologies