Clinical trials: Labour
Induced; Birth, Pregnancy
Comparison of Patient Satisfaction With Home Induction and In-patient Induction.
Induced labour is a medical intervention designed to initiate or accelerate the childbirth process when clinically indicated. Induced labour concerns 25.8% of pregnant women in France, according to the latest National Perinatal…
- Trial name
- NCT06272591
- Testing
- Preliminary search in the patient's file, A posteriori research in the patient's file, First questionnaire : choice of induction method reason for choice
- Where
- France
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain
Tsui Test as a Predictor of Bupivacaine Consumption in Labour Epidurals
Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations.
- Trial name
- NCT00792311
- Testing
- Tsui test
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Complication
Paperless Parotograph in Evaluation of Labour
Using Paperless partograph management of labour as simple tool to prevent obstructed labour or prolonged labour or its complications at the mother or her fetus
- Trial name
- labourRecord (NCT03272282)
- Where
- 2 sites in Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Assiut University
Birth; Delayed
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour
In a randomized control trial conducted in six study centers/labour wards in Sweden, consenting nulliparous women in active phase of labour and with a defined delayed labour progress will be randomized to receive a regimen of…
- Trial name
- OxyHighLow (NCT01587625)
- Testing
- Oxytocin
- Where
- 2 sites in Sweden
- Volunteers
- 1,376 people
- Sponsor
- Göteborg University
Pregnancy
Cervical Ripening Balloon in Induction of Labour at Term
About 1 in 6 deliveries in KKH are induced with prostaglandins. Inpatient induction can be a lengthy process especially when cervical priming is required.
- Trial name
- CRBII (NCT02620215)
- Testing
- Cervical Ripening Balloon, Prostin
- Where
- Singapore
- Volunteers
- 417 people
- Sponsor
- KK Women's and Children's Hospital
Pruritis, Hypotension Drug-Induced
Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.
The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women.
- Conditions
- Pruritis, Hypotension Drug-Induced, Urinary Retention, Fetal Bradycardia During Labor
- Trial name
- NCT07187427
- Testing
- Spinal analgesia, Epidural Analgesia
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Justine's Hospital
Postdural Puncture Headache
Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural
Accidental dural puncture is a potential complication of epidural analgesia for labour and delivery. When it happens, it may cause debilitating headaches and other symptoms that prevent mothers from talking care of their…
- Trial name
- NCT00465166
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Adults, Female
Pain Science Education for Labour and Postpartum Pain
This Delphi study aims to establish expert consensus on the role, content, and delivery of pain science education (PSE) for labour and postpartum pain management.
- Conditions
- Adults, Female, Labour Pain, Postpartum Pain
- Trial name
- PNE-DELPHI (NCT07096661)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Induction of Labor
A Randomized Trial of Oral Misoprostol Alone Versus Oral Misoprostol Followed by Oxytocin for Labour Induction
The primary objective of the trial is to assess the following: In women who have undergone cervical preparation with oral misoprostol as part of labour induction for hypertensive disease in India, is augmentation using oral…
- Trial name
- MOLI (NCT03749902)
- Testing
- Oral misoprostol, Oxytocin
- Where
- 3 sites in India
- Volunteers
- 520 people
- Sponsor
- University of Liverpool
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Labour;Obstructed, Labor Dystocia
Propranolol for Protracted Labor
Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor [1].
- Trial name
- PRO-Labor (NCT04741698)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Preterm Labour
Are Uterine Natural Killer Cells Involved in the Initiation of Preterm Labor ?
Research question: Population of study: women diagnosed as term pregnancy in labor (control) and the other group diagnosed as preterm labor (cases). Intervention: measuring uterine natural killer cells .
- Trial name
- NCT02284867
- Testing
- immunohistochemistry study
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Labor Pain
Assessment of Sensory Block During Labour Epidural Analgesia in Patients Experiencing Pain During First Stage of Labour.
Epidural analgesia is the gold standard for pain control during labour and an essential component of delivering effective and safe epidural analgesia is the assessment of the epidural sensory block.
- Trial name
- NCT05881395
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Preterm Labour
Single Versus Combination Therapy in Acute Tocolysis
The purpose of this study is to compare the tocolytic efficacy, effectiveness and safety of Atosiban in comparison with the combination of Atosiban and Nifedipine together.
- Trial name
- NCT01429545
- Testing
- Atosiban, Atosiban and nifedipine
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tawam Hospital
Prolonged Labor
Amniotomy and Oxytocin for Augmentation of Labour
Prolonged labour is a cause of maternal mortality and morbidity and perinatal mortality and morbidity. Prolonged labour is most often defined as onset of regular , rhythmical painful contractions accompanied by cervical…
- Trial name
- AOAL (NCT02318121)
- Testing
- Amniotomy first, Oxytocin first, Amniotomy and oxytocin
- Volunteers
- 150 people
- Sponsor
- Assiut University
Preterm Birth
Atosiban Versus Placebo in the Treatment of Late Threatened Pre-term Birth
The aim of this study is to investigate if tocolysis with atosiban in late preterm birth (30 to 34 weeks) is (cost-) effective compared with placebo in improving neonatal morbidity and mortality.
- Trial name
- APOSTEL 8 (NCT05693688)
- Testing
- Atosiban
- Where
- Netherlands
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Primigravida in Labour Pains
Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.
- Trial name
- NCT01205360
- Testing
- Bupivacaine-Fentanyl Mixture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Primary Postpartum Haemorrhage
Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.
Postpartum haemorrhage is the leading cause of maternal haemorrhage globally. With active management of labour 3 to 16.5% of parturients still experience postpartum haemorrhage.
- Trial name
- NCT02424201
- Testing
- Misoprostol, vitamin c
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Lagos State University
Gestational Diabetes, Gestational Diabetes Mellitus
Gestational Diabetes: Induction Versus Expectant Management of Labour
The purpose of this study is to determine whether, in Gestational Diabetes Mellitus (GDM) pregnancies, induction of labour at 38-39 weeks of pregnancy is superior to expectant management in terms of maternal and neonatal outcomes.
- Conditions
- Gestational Diabetes, Gestational Diabetes Mellitus, Diabetes Mellitus, Gestational, Pregnancy-Induced Diabetes
- Trial name
- GINEXMAL (NCT01058772)
- Testing
- INDUCTION of LABOUR
- Where
- 9 sites in Israel, Italy and 3 more
- Volunteers
- 425 people
- Sponsor
- IRCCS Burlo Garofolo
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva