Clinical trials: Labour
Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery
Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour
Catheterisation is an accepted tool in intrapartum bladder care and indwelling catheters are used routinely before elective caesarean sections.
- Conditions
- Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery, Catheter Infection
- Trial name
- NCT03914144
- Testing
- Catheter insertion
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Postpartum Hemorrhage
Comparison of Inhaled Oxytocin (IH) With Intramuscular (IM) Oxytocin in Pregnant Women and With Intravenous (IV) Oxytocin in Healthy Non-pregnant Women
The study will evaluate a stable, dry-powder formulation of oxytocin, with the goal of reducing post-partum hemorrhage morbidity and mortality in resource poor settings.
- Trial name
- NCT02999100
- Testing
- IH Oxytocin, IM Oxytocin, IV Oxytocin
- Where
- 3 sites in Australia, United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Labor Pain
Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
The study aims to investigate the effects of a combination of Lamaze breathing exercises and backside massage on the labor experiences of primigravidae in Pakistan.
- Trial name
- NCT06304311
- Testing
- Routine Obstetrics care & Lamaze breathing techniques and backside massage, Routine obstetrics care
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Preterm Pregnancy, Preterm Birth
Prediction of the Onset of Term and Preterm Labour
This study will collect samples from pregnant women in order to identify biomarkers that relate to onset of spontaneous preterm labour.
- Conditions
- Preterm Pregnancy, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane
- Trial name
- PREDICT (NCT04590677)
- Testing
- Samples required from group 1 (procedure within observational study), Samples required from group 2 (procedure within observational study)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Postpartum Hemorrhage
Intramuscular Versus Intravenous Prophylactic Oxytocin for Hemorrhage After Vaginal Delivery
Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour following vaginal delivery: A randomised controlled trial
- Trial name
- oxytocin (NCT02080104)
- Testing
- intarvenous and intramusculer 10 IU oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Hediye Dagdeviren
Intrapartum Fetal Monitoring, Pregnancy
Feasibility and Acceptability of the Combination of Propess and AN24 Monica for Outpatient Labour Induction (PRAM)
In order to confirm the feasibility of home monitoring with Monica AN 24, a licensed portable device for measuring fetal and maternal electrocardiogram (ECG), and the feasibility of inpatient monitoring with Monica AN 24 in…
- Trial name
- PRAM (NCT01026948)
- Testing
- Dinoprostone, Monica AN 24
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Liverpool Women's NHS Foundation Trust
Uterine Rupture Gravid
Uterine Rupture International Data Acquisition
Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality.
- Trial name
- URIDA (NCT03576950)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Labor Induction
Effect of Dexamethasone on Labour Induction in Term Pregnancies
The aim of the study is to assess the effect of dexamethasone on labour induction in term pregnancies. Primary outcome: The interval between initiation of induction and beginning of the active phase of labour.
- Trial name
- NCT07109258
- Testing
- Dexamethasone (Decadron) 8mg IM injection, Misoprostol 25 mcg, Both Misoprostol 25 mcg & Dexamethasone 8mg IM injection
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
First Pregnancy
Deambulatory Epidural During the Labour
Assess the impact of instrumentation and caesarean related to dyskinesia by reducing the concentration of local anesthetic and therefore the motor block.
- Trial name
- NCT02264834
- Testing
- Levobupivacaine 0.1% + Sufentanil 0.2µg/ml, Levobupivacaine 0.07% + Sufentanil 0.3µg/ml, Lumbar epidural analgesia
- Where
- Belgium
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Dr Madeleine Wilwerth
Labor Complication
Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Brief Background: The partograph is a graphical representation of the events in the first stage of labour. It is an instrument used in monitoring the well being of both the pregnant woman and her fetus (es) as they go through the…
- Trial name
- NCT05837559
- Testing
- Korle-Bu Modified WHO Partograph for Uncomplicated Labour
- Where
- Ghana
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Labor Long
Evaluation of Transperineal US in Labour
Assessment of progress of labour is an important step in decision making of obstetricians
- Trial name
- NCT03471780
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Premature Labor
Performance of the Monica Novii Wireless Patch System in Threatened and Actual Pre-Term Labour
To study the equivalence of the Monica Novii™ Patch System in patients admitted for threatened pre-term labor and for pre-term labor \& delivery from 32 +0 weeks gestation by determining the equivalence of the Novii™ Patch System…
- Trial name
- NCT03223324
- Testing
- abdominal fetal/maternal monitor
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Monica Healthcare Ltd
Labour, Childbirth
A Comparison of Intrapartum Epidural Fixation Devices: A Randomised Controlled Trial
A number of methods are currently used to prevent movement of epidural catheters in women during labour. These usually consist of sticky dressings applied to the patient's back.
- Trial name
- NCT02131090
- Testing
- Tegaderm TM, Lock-it Plus, Epifix
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- St George's, University of London
Preterm Labor
Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour.
The aim of the current study is to assess the accuracy of maternal serum amyloid A for prediction of preterm labor in women with threatened preterm labor.
- Trial name
- NCT03205020
- Testing
- serum amyloid a test
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- mona nematallah
Premature Rupture of Fetal Membranes
Intravenous Papaverine for Term Prelabor Rupture of Membranes
This randomized, double-blind, placebo-controlled trial evaluates whether intravenous papaverine, administered as an adjunct to oxytocin, shortens the time to delivery in women with term premature rupture of membranes (PROM).
- Trial name
- NCT07826533
- Testing
- Papaverine
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Wolfson Medical Center
Labor Pain
Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy
Childbirth is one of the most painful events that a woman is likely to experience, and thus is a major concern for most parturient.
- Trial name
- Oksiobs (NCT01016821)
- Testing
- Oxycodone
- Where
- Finland
- Volunteers
- 15 people
- Sponsor
- Kuopio University Hospital
Labour Duration, Primigravida
Valethamate Bromide Versus Hyoscine Butyl Bromide in Reducing Labour Duration Among Primigravida
Labour is a physiological process that enables the natural delivery of fetus, placenta and membranes after the age of viability.
- Trial name
- NCT07474350
- Testing
- Valethamate Bromide, Hyoscine butylbromide, Sterile water
- Where
- Nigeria
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Obstetric Labour, Premature
Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women
This study in healthy, adult Japanese women will characterize the PK, safety and tolerability of retosiban at the therapeutic doses planned to be evaluated in Phase 3.
- Trial name
- NCT02377414
- Testing
- Retosiban solution for Infusion
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Haemorrhage
A Non-investigational Product (IP) Study to Investigate Lung Function in Women in the Third Stage of Labour
The purpose of this study is to record and compare the inhalation profiles of non pregnant women and those who are in the third stage of labour.
- Trial name
- NCT02106000
- Testing
- Inhalation profile recorder
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline