Clinical trials: Labour
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Labor Long
The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae
This study compares the duration of active phase of labour in women who received buscopan and those who don't.
- Trial name
- NCT04349722
- Testing
- Hyoscine Butylbromide
- Where
- Malaysia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Latent Phase Labour
Early Labour Assessment and Support at Home
To determine, among healthy first time mothers who are uncertain as to when to come to hospital in labour, if home visits by obstetrical nurses compared to telephone advice have an impact on reducing cesarean section rate.
- Trial name
- NCT00225329
- Testing
- Labour assessment and support
- Volunteers
- 1,466 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Analgesia, Epidural
Comparison of Safety and Efficacy Between PIEB and CEI for Labour Epidural Analgesia
The goal of this clinical trial is to compare safety and efficacy of programmed intermittent epidural bolus (PEIB) and continuous epidural infusion (CEI) in parturients during active phase of labour.
- Trial name
- NCT06889285
- Testing
- Continuos epidural infusion, Programmed intermittent epidural bolus
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- Hospital Universiti Sains Malaysia
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Labour Pain
Testing the Efficiency of a Device Meant to Relieve Labour Pain
The suggested research is aimed to test the effectiveness of an external mechanical device to be applied and used by the parturient herself in pain relieving during labour .
- Trial name
- NCT00426725
- Testing
- EasyLabour
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- ACU Medical Technologies Ltd
Quality Health Care
Dural Puncture Epidural Vs Standard Epidural Technique in Parturient Receiving Continuous Labour Epidural Infusion
The goal of this study is to evaluate the quality and safety of labor analgesia by comparing the use of Dural puncture epidural technique to Standard epidural technique while maintaining labor analgesia by means of continuous…
- Trial name
- NCT06653036
- Testing
- Dural puncture epidural, Standard Epidural Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dystocia
Use of Acupuncture for Stimulation of Labour
Hypothesis:Acupuncture can be used as stimulation of labour in case of primary og secondary inertia. A randomized controlled trial including 150 pregnant women Acupuncture has become a natural part of the range of obstetric…
- Trial name
- NCT00279071
- Testing
- Acupuncture og acupressure when diagnosed with dystocia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Preterm Labour, Cervical Insufficiency
Intramuscular vs Rectal Progesterone in Preventing Preterm Labour After Cervical Cerclage
Preterm labour is a major cause of neonatal morbidity and mortality worldwide. Progesterone supplementation is known to help reduce the risk of preterm birth in high-risk women.
- Conditions
- Preterm Labour, Cervical Insufficiency, Pregnancy, High-Risk
- Trial name
- PROCER (NCT07307092)
- Testing
- Intramuscular Progesterone, Rectal Progesterone
- Where
- Pakistan
- Volunteers
- 820 people
- Sponsor
- Hina Mukhtar
Obstetric Labor Complications, Stillbirth
The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
OVERALL OBJECTIVE In an East African referral hospital, to develop and analyze the effect of locally agreed and achievable guidelines and a continual in-house training program for strengthening partogram-based…
- Conditions
- Obstetric Labor Complications, Stillbirth, Maternal Death
- Trial name
- PartoMa (NCT02318420)
- Testing
- The PartoMa intervention
- Where
- Tanzania
- Volunteers
- 3,087 people
- Sponsor
- Ib Christian Bygbjerg
Breakthrough Pain
Comparison of Regimens MPIB, CIPCEA, PCEA
Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload.
- Trial name
- COLEUS (NCT02278601)
- Testing
- epidural delivery system, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 839 people
- Sponsor
- KK Women's and Children's Hospital
Pain Management in Pregnant Women, Remifentanil
The Experience of Giving Birth With Remifentanil for Pain Relief: A Qualitative Study of Mothers and Midwives
Background: Remifentanil is an ultra-short-acting opioid used for labor pain relief in several countries, offering stronger analgesia than nitrous oxide but less than epidural anesthesia.
- Conditions
- Pain Management in Pregnant Women, Remifentanil, Midwife, Qualitative Research
- Trial name
- NCT07030777
- Where
- 3 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Nordsjaellands Hospital
Induced Vaginal Delivery
Can Cervical Stiffness Predict Successful Vaginal Delivery After Induction of Labour?
The purpose of this study is to determine if a new antenatal test of cervical stiffness can be used to predict which patients will have a successful vaginal delivery following an induction of labour.
- Trial name
- CASPAR (NCT05981469)
- Testing
- Cervical Stiffness Assessmenr, Bishop's Score Assessment
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Dystocia
A Comparative Study of the Effect of Two Partographs on the Cesarean Section Rate in Women in Spontaneous Labour
In the 2010-french perinatal survey, the overall cesarean section (CS) rate during labour was 21 % and 16% to 38% in case of dystocia.
- Trial name
- PARTODYS (NCT02741141)
- Testing
- New partograph based on the studies of Neal and Lowe, Classical partograph
- Where
- France
- Volunteers
- 633 people
- Sponsor
- University Hospital, Strasbourg, France
Labor Pain
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction.
- Trial name
- NCT06572241
- Testing
- Intrathecal morphine
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Childbirth Experience, Urinary Retention
Analgesia in the Second Stage of Labour
This study investigates efficacy, safety and childbirth experience in women receiving pudendal block during the final stage of delivery. It is an observational study and half of included primarous women recieve a pudendal block.
- Conditions
- Childbirth Experience, Urinary Retention, Satisfaction, Personal, Pain, Obstetric
- Trial name
- ASL (NCT04391075)
- Testing
- Pudendal nerve block
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Post Operative Pain
Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain
Caesarean section is a common method of delivery in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique.
- Trial name
- NCT03513237
- Testing
- Cervical dilation
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pre-conceptional Obesity
Leukocytes - ObeSity - Spontaneous Labour
This is a single-centre observational, prospective study carried out at the maternity unit of Dijon CHU. It will include pregnant women with a pre-conception BMI ≥ 30 kg/m² and will evaluate in these patients, the activation and…
- Trial name
- LOST (NCT02085772)
- Testing
- Blood samples at 37-38 Weeks of amenorrhea, Blood samples at 41 Weeks of amenorrhea if prolonged pregnancy, Blood samples at the time of delivery
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Labor Pain
Intranasal Fentanyl in Treatment of Labour Pain
Physiological changes during pregnancy are known to affect the pharmacokinetics of many drugs. Intranasal fentanyl is an interesting option for obstetric analgesia, but its use in pregnant patients has not been established.
- Trial name
- fentaobs (NCT02571179)
- Testing
- intranasal fentanyl 50 microg dose up to 250 microg
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Kuopio University Hospital
Threaten Preterm, Prethrem Labour
The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial
The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days…
- Conditions
- Threaten Preterm, Prethrem Labour, Bacterial Vaginitis
- Trial name
- NCT07344064
- Testing
- Gynoflor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand