Clinical trials: Labour
Adults, Female
Pain Science Education for Labour and Postpartum Pain
This Delphi study aims to establish expert consensus on the role, content, and delivery of pain science education (PSE) for labour and postpartum pain management.
- Conditions
- Adults, Female, Labour Pain, Postpartum Pain
- Trial name
- PNE-DELPHI (NCT07096661)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Labor Complication, Cervix; Open
4 Versus 6 cm Active Phase of Labour
A study to compare maternal and perinatal outcome between 4 and 6 cm cervical dilatation at amniotomy.
- Trial name
- NCT05339399
- Testing
- oxytocin augmentation
- Where
- Malaysia
- Volunteers
- 155 people
- Sponsor
- National University of Malaysia
Labor, Premature, Premature Birth
A Proof of Concept Study Assessing the Effect of Four Different Single Bolus Intravenous Doses of FE200440 and Placebo on Stopping Preterm Labor
To determine the effects of four different single bolus doses of FE200440 administered intravenously on stopping preterm labour compared to placebo in pregnant women with advanced gestational age
- Trial name
- NCT00209326
- Testing
- FE200440
- Where
- 17 sites in Belgium, Czechia and 4 more
- Volunteers
- 163 people
- Sponsor
- Ferring Pharmaceuticals
Third Stage of Labour
Oxytocin Administration in the Third Stage of Labour - A Study of Appropriate Route and Dose
Mothers are given the medication oxytocin after birth to help the uterus (womb) contract and therefore reduce blood loss. In Canada, oxytocin is given either into the muscle of the thigh or into a vein.
- Trial name
- NCT00200252
- Testing
- oxytocin
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Labor; Prolonged, Second Stage, Delivery Problem
Maternal Position's Effect on Labor Progression in Occiput Posterior Deliveries
This is a randomized controlled experimental study to determine the effect of maternal position on the progression of labour in deliveries in which the foetus is in the occiput posterior position.
- Trial name
- NCT06928038
- Testing
- Positioned group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Childbirth
McRoberts Manoeuvre Or Pushing Study (McMOPS)
We propose to conduct a randomised-controlled study to investigate whether adopting McRoberts' position, after 45 minutes of active pushing with no signs of progress, can increase the probability of vaginal delivery, preventing…
- Trial name
- NCT00116246
- Testing
- McRobert's manoeuvre
- Where
- Australia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Labor Pain
Parturient Satisfaction With Epidural Analgesia by PCEA or Manual Boluses
Those prospective parturients that express that they may want an epidural labour analgesia for their delivery will be informed about the possibility to choose between a pump driven epidural or midwife administered intermittent…
- Trial name
- NCT06094946
- Testing
- Ropivacaine Hydrocloride, Fentanyl Citrate
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hospital HUS
Obesity, Induced; Birth
Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy
This study investigate the progression of labour in 144 normal weight pregnant women (BMI <30) and 144 obese pregnant women (BMI >30) , not in labor admitted for induction of labor.
- Trial name
- NCT02788305
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Epidural Top-up, Labour
Labour Epidural Top-up With Warmed Ropivacaine
The purpose of this study is to determine weather using warmed (body temperature) 0.75% Ropivicaine to convert labour epidural analgesia to surgical anaesthesia, reduces the onset time of surgical block, compared to standard room…
- Conditions
- Epidural Top-up, Labour, Caesarian Section, Ropivacaine
- Trial name
- LETWR (NCT02838329)
- Testing
- warming of ropivacaine for BT, Ropivicaine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Labor Pain
Continuous Remote Vital Sign Monitoring During Labour Analgesia With Remifentanil
Continuous remote vital sign monitoring during labour analgesia with remifentanil - a prospective observational study Remifentanil PCA represents a well-tolerated, effective and valuable option for labour analgesia, yet its wider…
- Trial name
- NCT07167498
- Testing
- Intermittent midwife absence during remote monitoring of remifentanil PCA in labour
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Pregnancy
Cervical Ripening Balloon in Induction of Labour at Term
About 1 in 6 deliveries in KKH are induced with prostaglandins. Inpatient induction can be a lengthy process especially when cervical priming is required.
- Trial name
- CRBII (NCT02620215)
- Testing
- Cervical Ripening Balloon, Prostin
- Where
- Singapore
- Volunteers
- 417 people
- Sponsor
- KK Women's and Children's Hospital
Primigravida in Labour Pains
Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.
- Trial name
- NCT01205360
- Testing
- Bupivacaine-Fentanyl Mixture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Labor Pain
Efficacy and Safety of Intravenous Paracetamol in Manament of Labour Pain
to compare between the use of single dose of paracetamol and pethidine hydrochloride intravenously in management of labour pains
- Trial name
- NCT04744727
- Testing
- paracetamol-pethidine
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Failed Induction of Labor
A Novel Protocol for Labour Induction
The use of foley catheter was tested many times and proved to be effective for induction of labour.
- Trial name
- NCT01506388
- Testing
- foley catheter, Misoprostol, Vaginal IMN
- Where
- 2 sites in Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy, Labour
Minimum Effective Dose (MED) & Epidural Bupivacaine
Local anaesthetics are highly toxic drugs. They can cause toxicity by an absolute overdose, accidental injection in a blood vessel or slow absorption from the area of injection.
- Conditions
- Pregnancy, Labour, Primigravida Labour, Epidural Block
- Trial name
- NCT02116842
- Testing
- 0.1% bupivacaine, 0.075% bupivacaine, 40 µg fentanyl
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Leeds
Preterm Labour
Monocyte Chemotactic Protein-1 (MCP-1) Expressing Monocytes to Predict Preterm Delivery: PhenoMAP Study
The threat of preterm labour (PTL) is the first cause of hospitalization in the course of pregnancy. Its diagnostic is based on clinical examination with a positive predictive value of about 40 %.
- Trial name
- PHENOMAP (NCT01340222)
- Testing
- biological samples
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Preterm Labor, Preterm Birth
Aspiration Technique-based Device for Preterm Labor
Premature birth (PTB, birth before 37 weeks of pregnancy) is a global, yet unsolved, problem. With a global amount of approximately 15 M babies born prematurely, PTB is the leading cause of perinatal morbidity and mortality in…
- Trial name
- PREGNOLIA (NCT05355649)
- Testing
- PREGNOLIA SYSTEM
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Labouring Parturients Requiring/Requesting Epidural Analgesia as Part of Their Peri-partum Care
A Comparison Study Of Two Different Techniques For Identifying The Epidural Space In Parturients In Labour
The purpose of this study is to determine whether the use of the Epidrum device to identify the epidural space in labouring parturients reduces morbidity, when compared to standard loss of resistance techniques.
- Trial name
- NCT01574391
- Testing
- Epidrum
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Labour Duration and Metoclopramide
Metoclopramide and the Length of First Stage of Labor , a Randomized Controlled Trial
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being and for the providers of the birth services.
- Trial name
- NCT04969120
- Testing
- Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Relief During Labour
Determination of the Minimum Local Analgesic Dose of Spinal Chloroprocaine in Labour
Combined spinal-epidural (CSE) analgesia has become a widely accepted approach to provide analgesia for labour pain. Despite the increasingly widespread use of this technique, an optimal intrathecal drug regimen has not been…
- Trial name
- NCT01909089
- Testing
- Spinal administration of chloroprocaine.
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent