Clinical trials: Lactate
Buttock Contouring, Buttock Lifting
Efficacy and Safety of Poly-L-lactic Acid
This is a phase IV prospective, multicentre, single cohort, open-label clinical trial evaluating the efficacy and safety of Poly-L-lactic acid (Sculptra® Aesthetic) for the treatment of contour deformities of the buttocks region
- Trial name
- NCT03922464
- Testing
- Poly-L-lactic acid (Sculptra® Aesthetic)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Dry Skin
This Was a Clinical Study Investigating the Moisturization and Desquamation Effect of AmLactin® Rapid Relief Restoring Lotion + Ceramides on Dry Skin in Healthy Female Volunteers. AmLactin® Rapid Relief is an Over-the-counter Cosmetic
The primary objective of this study was to investigate if AmLactin® Rapid Relief improves the skin through desquamation and moisturization via D-SQUAME analysis. AmLactin® Rapid Relief is an over-the-counter cosmetic.
- Trial name
- NCT04085809
- Testing
- AmLactin® Rapid Relief
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Sandoz
Sepsis, Lactate Blood Increase
Blood Lactate Level for Pre-hospital Orientation of Septic Shock
In the pre-hospital setting, the severity assessment of septic shock is essential to decide the optimal initial in-hospital level of care.
- Trial name
- LAPHSUS (NCT03831685)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hôpital Necker-Enfants Malades
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Exercise, Lactate
Minimally-Invasive Realtime Assessment of Continuous Lactate in Exercise
Lactate is a compound produced as a by-product of glycolysis. The increase in lactate concentration can result from a variety of causes, such as during anaerobic metabolism in exercise or haemodynamic shock in conditions such as…
- Trial name
- MIRACLE (NCT04238611)
- Testing
- Microneedle, Blood lactate measurement, Exercise regimen
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Wounds, Infections
Acid Base and Electrolytes Patterns in Drains Operational Wounds and Its Relation to Complications
Objective- The purpose of this study is to evaluate a connection between PH,PCO2,HCO3,PO2,Na,K,Glu and Lactate patterns in vacuum drains of different plastic operational wounds and its relation to infections and seroma formation.
- Conditions
- Wounds, Infections, Seroma
- Trial name
- NCT01454167
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Flaccidity, Muscle
Efficacy and Safety of Poly-L-lactic Acid
This study aims to assess efficacy and safety of Sculptra in the treatment of skin flaccidity in selected areas - arms, anteromedial region, and gluteal regions.
- Trial name
- Sculptra (NCT03225066)
- Testing
- Poly-L-lactic acid - Sculptra
- Where
- 4 sites in Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Galderma Brasil Ltda.
Skin Aging, Wrinkles
Poly-L-lactic Acid (PLLA) Injection for Neck Skin Laxity: A Pilot Study
Skin aging of the neck commonly leads to wrinkles and skin laxity due to the gradual loss of collagen and structural support in the skin.
- Trial name
- NCT07689344
- Testing
- Poly-L-Lactic Acid (Sculptra) injection
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Hygiene
Dermacyd PH_DESILSTY_FR (Lactic Acid) - Compatibility - Stay on Frutal
Primary Objective: To demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd PHDESILSTYFR.
- Trial name
- NCT00933907
- Testing
- LACTIC ACID(ND)
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sanofi
Cellulite
Clinical Trial of Poly-L-lactic Acid (Sculptra Aesthetic) for the Treatment of Cellulite of the Buttocks and Thighs
clinical trial is to assess the safety, efficacy and patient satisfaction associated with the treatment of cellulite of the buttocks and thighs with injectable poly-L-lactic acid (PLLA), or Sculptra® Aesthetic
- Trial name
- NCT04830722
- Testing
- Sculptra Aesthetic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Hygiene
Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Photo Evaluation.
To demonstrate the absence of photoirritation and photosensitization potential of the product Dermacyd PHDETINLYN Sweet Flower.
- Trial name
- NCT00785590
- Testing
- Dermacyd PH_DETINLYN (Lactic Acid)
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sanofi
Necrotizing Enterocolitis
Analysis of Integrated Clinical, Laboratory and Prognostic Data of Neonates With Necrotizing Enterocolitis
This is a retrospective study led by The Sixth Affiliated Hospital, Sun Yat-sen University, focusing on newborns diagnosed with necrotizing enterocolitis (NEC)-a serious gastrointestinal disease that threatens newborns'…
- Trial name
- ACLPNEC (NCT07207915)
- Testing
- Observational retrospective cohort study
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Swimming, Coordination Lack
Swimming Economy in Swimmers and Paraswimmers as a Function of SR(Stroke Rate) and V(Velocity) Manipulations (NePTUNE-3)
The competitive swimming and open water swimming events are scheduled for the 2024 Paris Olympic and Paralympian Games. Generally associated with a non-neglectable number of medals in the last Olympics, swimming performance…
- Conditions
- Swimming, Coordination Lack, Oxygen Consumption, Lactic Acid Blood Increased
- Trial name
- NePTUNE-3 (NCT05011591)
- Testing
- Swimming economy
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Rouen Normandie
Skin Laxity
Injectable Poly-L-Lactic Acid for Volumization and Adipogenesis of the Hip Dell
To assess the safety, efficacy and subject satisfaction associated with volumization of the hip dell with injectable poly-L-lactic acid (PLLA), or Sculptra® Aesthetic (Galderma Laboratories, Fort Worth, TX).
- Trial name
- NCT05269654
- Testing
- injectable poly-L-lactic acid, Normal Saline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Metabolic Flexibility
Astaxanthin Reduces Exercising Heart Rate.
Briefly, this study involved 2 trials: baseline (Trial 1) and post-astaxanthin intervention (Trial 2). Both trials included participants completing a graded exercise test while connected to a metabolic cart, to measure…
- Trial name
- NCT05282355
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of North Alabama
Healthy Adult Male
Short-Term Broccoli Supplementation and Acute Oxidative Stress Recovery
The study aimed to evaluate the effects of short-term broccoli powder supplementation on metabolically demanding exercise performance, muscle power, and blood lactate recovery.
- Trial name
- NCT07454265
- Testing
- Broccoli powder
- Where
- Lithuania
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Circadian Rhythm
Effect of Circadian Rhythm on Brain NAD Measured by Phosphorus Magnetic Resonance Spectroscopy at 7 Tesla
The Discovery of the circadian clock first established a genetic basis for behavior, and our understanding of circadian rhythm (CIR) has since expanded to provide molecular insights into physiology and disease.
- Trial name
- ChronoBrain (NCT05093088)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
LBSL, Leukoencephalopathies
Quantifying Disease Progression in LBSL
Leukoencephalopathy with brain stem involvement and lactate elevation (LBSL) is a genetic disorder caused by biallelic mutations in the DARS2 gene that encodes mitochondrial aspartyl tRNA synthase.(1, 2) It is characterized by…
- Trial name
- LBSL (NCT05750979)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- M. Engelen
Sensitive Skin
TRPV Expression in Subjects With Sensitive Skin
Sensitive skin syndrome is defined as the presence of burning, itching or any other unpleasant sensation on the skin, due to physical, chemical or psychological factors.
- Trial name
- NCT01871883
- Testing
- Skin biopsy, Oral mucosa specimen
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Hygiene
Lactacyd Radiance (Lactic Acid) Prophetic Patch Test
Primay objective: To evaluate the potential of the products in eliciting adverse skin reaction.
- Trial name
- NCT00679562
- Testing
- Lactic Acid, Distilled water
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanofi