Clinical trials: Lactation Disorders
Low Milk Supply, Pre-diabetes
Metformin to Augment Low Milk Supply (MALMS) Study
Most new mothers in the United States will start off breastfeeding. For some mothers, despite following best practices, they are not able to meet their breastfeeding goals due to unexplained low milk supply.
- Conditions
- Low Milk Supply, Pre-diabetes, Insulin Resistance, Suppressed Lactation
- Trial name
- MALMS (NCT02179788)
- Testing
- Standard care, Metformin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Preterm Infant, Breast Feeding
Positive Feeding of the Preterm Infant
The goal of this feasibility study is to assess the feasibility to implement a feeding strategy for preterm infants. The main questions it aims to answer are: Is it feasible to implement the PoP-intervention in a level 3a…
- Conditions
- Preterm Infant, Breast Feeding, Bottle Feeding, Enteral Feeding
- Trial name
- PoP (NCT06189352)
- Testing
- Positive feeding of the preterm infant
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Premature Birth, Theory, Double Bind
The Meleis Theory on Postpartum Depression, Breastfeeding, and Maternal Self-Efficacy in Women Experiencing Preterm Birth
The aim of this study was to evaluate the effect of a nursing approach based on Meleis' Transition Theory on postpartum depression, maternal self-efficacy and breastfeeding self-efficacy in women who gave birth preterm.
- Conditions
- Premature Birth, Theory, Double Bind, Postpartum Depression, Breast Feeding
- Trial name
- NCT06250933
- Testing
- Postpartum Maternal Care and Premature Infant Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Covid19, Breastfeeding
Gestational Immunity for Transfer
This is a study prospective cohort study at an urban academic centre, with two parts: 1. Health outcomes, and maternally transferred antibodies, in babies born to mothers who had antenatal COVID-19 and convalesced before…
- Conditions
- Covid19, Breastfeeding, Vaccine Exposure Via Breast Milk
- Trial name
- GIFT (NCT04802278)
- Testing
- COVID-19 vaccine
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding
Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the Newborn
Frenotomy of tongue-tie is commonly performed to resolve breastfeeding difficulties, eg maternal nipple pain and infant's latching difficulties. The procedure carries minor discomfort for the infants.
- Conditions
- Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding, Neonatal Latch Difficulties
- Trial name
- NCT01274247
- Testing
- Topical Benzocaine
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postpartum Depression (PPD), Breastfeeding
Methyl Donor-Rich Diet in the Postpartum Period
This study aims to evaluate the effects of a methyl-donor-rich diet during the postpartum period on maternal depression, breastfeeding success, and infant weight.
- Conditions
- Postpartum Depression (PPD), Breastfeeding, Maternal Nutrition, Infant Development
- Trial name
- NCT07887178
- Testing
- Methyl Donor-Rich Dietary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Ankyloglossia
Efficacy of Neonatal Release of Ankyloglossia
The purpose of this study is to determine if frenotomy for ankyloglossia will improve infant breastfeeding, decrease maternal nipple pain and increase duration of breastfeeding with the hypothesis that frenotomy will do all of…
- Trial name
- NCT00967915
- Testing
- Frentomy
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Pain, Post Partum Depression
Vaginal Postpartum Pain Management Protocol Comparison
Untreated postpartum pain has been associated with increased risk of opioid use, postpartum depression and development of persistent pain.
- Conditions
- Pain, Post Partum Depression, Opioid Use, Breast Feeding
- Trial name
- NCT04087317
- Testing
- Paracetamol 1000 Mg Oral Tablet, Ibuprofen 400Mg Tab, Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus
Breast Feeding, Hypertension
Maternal Treatment With ACE-inhibitors and Breastfeeding: a Mono-centric Study on the Exposure Through Breast Milk
The ACE-inhibitors is one group of essential medication for which reliable data on the safety during breastfeeding is lacking. ACE inhibitors are indicated for several severe or life-threatening disorders like hypertension, heart…
- Conditions
- Breast Feeding, Hypertension, Heart Failure, Proteinuria
- Trial name
- NCT06088849
- Testing
- Venipuncture
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breastfeeding, Postpartum Depression (PPD)
Telehealth-Supported Breastfeeding Counseling in Primiparous Mothers
Breastfeeding is critical for infant and maternal health; however, many first-time mothers experience difficulties that may lead to early discontinuation of breastfeeding.
- Conditions
- Breastfeeding, Postpartum Depression (PPD), Breastfeeding Self-Efficacy
- Trial name
- TELE-BF (NCT07396415)
- Testing
- Telehealth-Supported Breastfeeding Counseling, Routine Postpartum Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Thiamin Deficiency
Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia
The purpose of this study is to determine whether consumption of thiamin fortified fish sauce over 6 months increases the thiamin status of women to a level consistent with a low risk of infantile beriberi.
- Trial name
- NCT02221063
- Testing
- Thiamin fortified fish sauce (low concentration), Thiamin fortified fish sauce (higher concentration)
- Where
- Cambodia
- Volunteers
- 366 people
- Sponsor
- University of British Columbia
Diet, Food, and Nutrition, Exercise
The NutriNet-Santé Study
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between…
- Conditions
- Diet, Food, and Nutrition, Exercise, Diseases Category, Cohort Studies
- Trial name
- NCT03335644
- Where
- France
- Volunteers
- 170,000 people, healthy volunteers welcome
- Sponsor
- University of Paris 13
Breast Engorgement, Lactation Disorders
Auricular Therapy and Basic Care for Blocked Milk Ducts After Cesarean Delivery
The goal of this clinical trial is to evaluate whether auricular acupressure combined with basic care can improve symptoms in postpartum women with blocked milk ducts after cesarean delivery.
- Trial name
- NCT07561099
- Testing
- Auricular Acupressure, Basic Breast Care
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Vitamin D Deficiency, Rickets
Vitamin D Supplementation in Breastfeeding Women
Adequate vitamin D is essential for proper infant growth and development. However, human milk is low in vitamin D, and most infants do not receive recommended supplementation.
- Conditions
- Vitamin D Deficiency, Rickets, Infant Nutrition Disorders
- Trial name
- NCT01240265
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Milk Production, Human Milk Feeding
Efficacy of Herbal Galactagogue Silitidil After Preterm Birth
After preterm birth mothers often suffer from hypogalactia. Herbal galactogogues can be used in order to increase milk production.
- Conditions
- Breast Milk Production, Human Milk Feeding, Hypogalactia, Preterm Infant Nutrition
- Trial name
- NCT03577587
- Testing
- Silitidil for 21 days
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Waldkrankenhaus Protestant Hospital, Spandau
Obesity
Effect of Exercise Training on Breastmilk Composition
The aim of this trial is to investigate whether regular endurance exercise during the lactation period will influence breastmilk composition among individuals with overweight/obesity, and secondarily to assess if such changes…
- Trial name
- MILKSHAKE (NCT05488964)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 74 people
- Sponsor
- Norwegian University of Science and Technology
Pre-Term, Breast Milk Expression
Preemie Milk Analyser Validation Study
This study aims to test and validate the Preemie Ecosystem- a new device and associated software package for measuring the nutrient (fat, protein and carbohydrate) content of the breast milk of the mothers of premature babies.
- Conditions
- Pre-Term, Breast Milk Expression, Nutrition Disorder, Infant
- Trial name
- NCT06486194
- Testing
- Targeted breast milk fortification using preemie device, Standard Breast milk fortification
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Sleep Initiation and Maintenance Disorders
Behavioral Insomnia of Childhood: Impact of Parent Education
Behavioral Insomnia of Childhood (BIC) is among the most prevalent problem presented to pediatricians with a reported occurrence of approximately 30% worldwide.The most widely applied treatment strategies for BIC in infants…
- Trial name
- NCT03320083
- Testing
- Educational care derived from POSSUMS
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postpartum Depression, Psychoeducation
Psychoeducatıon Interventıon Postpartum Depressıon Breastfeedıng
This study was planned to evaluate the effects of psychoeducation intervention for postpartum care on postpartum depression and breastfeeding.
- Conditions
- Postpartum Depression, Psychoeducation, Breastfeeding, Postpartum Care
- Trial name
- NCT06779903
- Testing
- the psychoeducation intervention program booklet, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Patient Satisfaction
Patient Satisfaction With Abbreviated Postpartum Magnesium Sulfate for Severe Preeclampsia
Preeclampsia is a common and potentially devastating disease that affects only pregnant or postpartum patients. It is a leading cause of maternal mortality not only worldwide, but in the United States as well.
- Trial name
- NCT05789381
- Testing
- Magnesium sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago