Clinical trials: Lactation Disorders
PAIN, PAIN MANAGEMENT
Triple Combination vs. Breastfeeding (Tetanalgesia) for Neonatal Pain Relief
This randomized clinical trial evaluated whether a non-pharmacological Triple Combination of expressed breast milk, sucking, and facilitated tucking reduced pain during heel prick in healthy term newborns compared with…
- Trial name
- NCT07777432
- Testing
- Triple Combination, Breastfeeding (Tetanalgesia)
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Universitat Jaume I
Lactation Suppressed, Cabergoline Adverse Reaction
Factors and Outcomes Associated With Postpartum Cabergoline Use
Cabergoline is frequently being requested by many postpartum women with a live newborn to suppress lactation. The aim of the study is to investigate which women desire such an intervention, and what side effects they are…
- Conditions
- Lactation Suppressed, Cabergoline Adverse Reaction, Postpartum DVT, Postpartum Depression
- Trial name
- NCT03965572
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Maternal; Malnutrition, Infant Malnutrition
Impact of Maternal Stress on Infant Stunting
This study takes place in rural Mam-Mayan communities of Guatemala characterized by high rates of childhood stunting. It aims to characterize women's exposure to nutrition, infection and psychosocial stressors vs.
- Conditions
- Maternal; Malnutrition, Infant Malnutrition, Physiological Stress, Emotional Stress
- Trial name
- NCT02755012
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- McGill University
Food Allergy, Cow's Milk Allergy
Early Supplementation for Cow's Milk Allergy Prevention
Cow's milk allergy (CMA) is a common food allergy in infants and young children that can have a significant impact on the individual and their family due to dietary restrictions, risk of nutritional deficiencies, social…
- Trial name
- ESCAPE-PL (NCT06652698)
- Testing
- Cow's milk formula [CMF], Amino-acid formula [AAF], Donor human milk [DHM]
- Where
- Poland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Breastfeeding, Preterm Infant
The Effect of the SNS-Based Feeding on Transition to Exclusive Breastfeeding in Preterm Infants
This study investigated the effect of the Supplemental Nursing System (SNS)-based feeding on the time to transition to exclusive breastfeeding, sucking success, and the time to discharge in preterm infants
- Conditions
- Breastfeeding, Preterm Infant, Sucking Behavior
- Trial name
- NCT05815706
- Testing
- MEDELA Supplemental nursing system
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Breast Milk Collection, Microbial Colonization
Storage Conditions and Breast Milk Microbiota Composition
Breast milk is the mainstay of newborn nutrition, providing all the nutrients and vitamins necessary for optimal growth of newborn infants.
- Trial name
- NCT05669690
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Infant and Young Child Feeding
Standardized Application of Feeding Evaluations Using SMART Tool
Premature and medically complex infants have delayed development of oral feeding skills, leading to prolonged hospitalization, costs, and family stress.
- Trial name
- SAFEST (NCT07136610)
- Testing
- SMART Tool
- Where
- 14 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Wake Forest University Health Sciences
Exclusive Breastfeeding
Status Report on Exclusive Breastfeeding and Predictive Factors at Martigues Hospital
Evaluate the prevalence of exclusive breastfeeding at M3 within the Martigues CH.
- Trial name
- EAME_FAP (NCT07046741)
- Where
- France
- Volunteers
- 309 people
- Sponsor
- Centre Hospitalier de Martigues
Multiple Sclerosis, Clinically Isolated Syndrome
A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab
This study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) [in line with the locally approved indications] treated with…
- Trial name
- SOPRANINO (NCT04998851)
- Testing
- Ocrelizumab
- Where
- 8 sites in United States, Spain and 1 more
- Volunteers
- 26 people
- Sponsor
- Hoffmann-La Roche
Malnutrition (Calorie), Infant Nutrition Disorder
Goat Milk-Derived Formula vs. Undiluted Goat Milk in Infants Unable to Exclusively Breastfeed: Growth and Biomarker Analysis
The goal of this clinical trial is to learn if Goat Milk-Derived Formula Alternatives (GMDFA) are safe and effective for infants who are unable to be exclusively breastfed.
- Conditions
- Malnutrition (Calorie), Infant Nutrition Disorder, Growth Flatering, Gut Microbiome
- Trial name
- GMDFA (NCT07225153)
- Testing
- GMDFA, Undiluted Goat Milk
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Aga Khan University
Weight Gain, Pregnancy, Microbial Colonization
Microbiome and Malnutrition in Pregnancy (MMiP)
Nutritional status during pregnancy plays an important role in maternal health and birth outcomes. While few factors impacting nutritional status during pregnancy have been identified, studies of undernutrition in children have…
- Conditions
- Weight Gain, Pregnancy, Microbial Colonization, Pregnancy Related, Pregnancy Loss
- Trial name
- MMiP (NCT05108675)
- Where
- Pakistan
- Volunteers
- 400 people
- Sponsor
- Aga Khan University
Pregnancy, Breastfeeding
The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months
The study's purpose is to determine if early (2-3 week) versus traditional (6-8 week) postpartum follow up is associated with a higher rate of breastfeeding at 6 months.
- Conditions
- Pregnancy, Breastfeeding, Contraception, Cervical Cancer
- Trial name
- NCT02221895
- Testing
- Postpartum follow up appointment 2-3 weeks after delivery, Postpartum follow up 6-8wk after delivery
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
High-risk Pregnancy, Breast Feeding
Effect of Hypnobreastfeeding Education in High-Risk Pregnant Women
It is thought that hypnobreastfeeding training given to high-risk pregnant women will reduce anxiety levels, increase lactation, encourage breastfeeding, reduce the perception of insufficient milk, and facilitate adaptation to…
- Trial name
- NCT07281339
- Testing
- Hypnobreastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Amasya University
Intrauterine Devices
Study on Medical Records of Women Using an Intrauterine Device (IUD) to Analyze the Risks That the IUD Will be Expelled or Perforates the Womb in Relation to Breastfeeding, the Point in Time When the IUD Was Inserted After Childbirth and in Relation to Different Types of IUDs
Study to analyze electronic medical records of women using an intrauterine device (IUD). The study was required by the FDA for the marketed IUD Mirena (US Post-marketing requirement; short name of study: APEX IUD).
- Trial name
- APEX IUD (NCT03754556)
- Testing
- Intrauterine device
- Where
- 4 sites in United States
- Volunteers
- 326,658 people, healthy volunteers welcome
- Sponsor
- Bayer
Breastfeeding, Breastfeeding Initiation
Birth & Breastfeeding Support Study
The goal of this observational study is to learn about the effects of birth practices such as cesarean section and vacuum assisted birth and diseases such as gestational diabetes and preeclampsia on exclusive breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Initiation, Breastfeeding Duration, Birth
- Trial name
- BABSS (NCT06844019)
- Where
- Denmark
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Malnutrition, Infant, Malnutrition, Child
Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan
Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2/1000 live births (LBs)) globally.
- Trial name
- NCT05590351
- Testing
- First diet: m-health coaching application, Face to Face counselling
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy, Gestational Diabetes
Behavior of Biomarkers During Pregnancy and Lactation Through a Biological Multi-paradigm Model: BECOME Study Protocol
Background Despite of advances in research, at the moment, various points related to the physiology of gestation and the etiology of severe diseases that can be developed in the course of it remain unknown.
- Conditions
- Pregnancy, Gestational Diabetes, Hypertension, Obesity
- Trial name
- BECOME (NCT02811172)
- Testing
- BEhavior of biomarkers during pregnanCy and lactatiOn
- Where
- Spain
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
LBW, Preterm
Effects of Kangaroo Mother Care Among Low Birth Weight (LBW) and Preterm Infants
Hypothermia, infections ,and ineffective breastfeeding are some of the commonest causes of deaths among premature and low birth weight LBW infants.
- Trial name
- KMC (NCT01776281)
- Testing
- Kangaroo Mother Care, Standard Care
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Aga Khan University
Breastfeeding, Exclusive
Diastolic Blood Pressure and Lipid Profile in Infants
The influence of early environmental factors, including nutrition, on future cardiovascular disease (CVD) risk and, in a broader view, the concept of early metabolic programming and future health have been extensively discussed…
- Trial name
- ERAhmed (NCT03612427)
- Testing
- S. Cholesterol S. Triglyceride
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sickle Cell Disease, Sickle Cell Anemia
Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation
The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.
- Trial name
- HELPFUL (NCT04093986)
- Testing
- Chart Review, Survey
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati