Clinical trials: Lactic Acid
Exercise-Induced Lactic Acidemia, Lactate Blood Increase
Lithothamnion Species on Blood Lactate During Exhaustive Exercise in Trained Cyclists
Deep ocean mineral water has been shown to improve exercise phenotypes in human and animal models. However, there is yet to be an investigation of Algae species such as Lithothamnion that absorb and concentrate these minerals.
- Trial name
- AAPt (NCT03980678)
- Testing
- Mineral Rich Algae
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Hygiene
Dermacyd Femina (Lactic Acid) Pocket BR - Photo Evaluation
To demonstrate the absence of photoirritation and photosensitization potential of the product Dermacyd Femina (Lactic Acid) Pocket BR.
- Trial name
- NCT00783640
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sanofi
Physical Inactivity
High-Intensity Interval Training and Monocyte Epigenetic Adaptation After Detraining
This randomized, work-matched training-detraining-rechallenge study evaluated whether repeated high-intensity interval training produces persistent functional and epigenetic adaptations in human monocytes.
- Trial name
- NCT07771075
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Training
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saif Rasheed Ghanim
Lactic Acidosis
Dichloroacetate Kinetics, Metabolism and Toxicology
Dichloroacetate (DCA) is a product of water chlorination and a metabolite of certain industrial solvents, thus making it a chemical of environmental concern.
- Trial name
- NCT00015015
- Testing
- Dichloroacetate
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
This Study Aims to Evaluate the Safety Profile and Tissue Changes After Biostimulatory Treatments to the Face in Healthy Volunteers
Analysis of Safety and Tissue Interaction of Injectable Biosmulators
The goal of this clinical trial is to analyse tissue changes in the pre-auricular region after injectable (Poly-L-Lactic-Acid/Calcium-Hydroxylapatit) biostimulatory interventions in healthy volunteers.
- Trial name
- Biostimulation (NCT06993558)
- Testing
- Poly-L-Lactic Acid (Sculptra) injection, Calcium Hydroxyapatite
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Healthy Volunteer, URTI
LC-Plasma for Preventing URTIs and Reducing Symptoms
The goal of this study is to evaluate the efficacy of the LC-Plasma in preventing upper respiratory tract infections (URTIs) in healthy volunteers. Researchers will compare LC-Plasma to placebo to see if LC-Plasma prevents URTIs.
- Trial name
- NCT06827327
- Testing
- LC-Plasma
- Where
- Australia
- Volunteers
- 637 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Parkinson's Disease, Multiple Sclerosis
Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients
Fatigue is one of the most common and debilitating symptoms experienced in Parkinson's Disease (PD) and Multiple Sclerosis (MS).
- Trial name
- PDMSLac (NCT02184494)
- Testing
- pro5 AIRdaptive Power Plate (Badhoevedorp, The Netherlands)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Florida State University
Skin Laxity
Injectable Poly-L-Lactic Acid for Volumization and Adipogenesis of the Hip Dell
To assess the safety, efficacy and subject satisfaction associated with volumization of the hip dell with injectable poly-L-lactic acid (PLLA), or Sculptra® Aesthetic (Galderma Laboratories, Fort Worth, TX).
- Trial name
- NCT05269654
- Testing
- injectable poly-L-lactic acid, Normal Saline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Renal Function Test, Urine Output, Lactate Level
Dopamine and Norepinephrine Infusion With Restricted Hydration
This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicator for tissue hypo perfusion…
- Trial name
- NCT03780686
- Testing
- Norepinephrine, dopamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Type 2 Diabetes, Obesity
Lactate and Glycerol Contribution to Gluconeogenesis
A major cause of increased blood glucose levels in type 2 diabetes (T2D) is increased hepatic gluconeogenesis (GNG), as the liver converts various substrates into glucose.
- Conditions
- Type 2 Diabetes, Obesity, Healthy
- Trial name
- NCT06955130
- Testing
- Glycerol, Lactate, Glucose
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Lax Skin, Knee
Sculptra Aesthetic for the Treatment of Upper Knee Skin Laxity
All subjects will receive three, single-sided injections of PLLA, performed 1 month apart.
- Trial name
- NCT03487172
- Testing
- poly-L-lactic acid to right knee, poly-L-lactic acid to left knee
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Stable Plaque Psoriasis
Comparing the Efficacy of Ultravate Ointment in Combination With Lac-Hydrin Lotion in the Treatment of Psoriasis
This is an investigator-masked, randomized, parallel, clinical study comparing the efficacy of once daily versus twice daily application of Ultravate® ointment (halobetasol propionate 0.05% ointment) in combination with…
- Trial name
- NCT00990561
- Testing
- Ultravate ointment twice daily + LacHydrin lotion twice daily, Ultravate ointment once daily + LacHydrin lotion twice daily
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Metabolism, Inborn Errors, Lipid Metabolism, Inborn Errors
Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy
This study aims to characterize the pathophysiological mechanisms of 21 different metabolic myopathies. The study will focus on exercise capacity and the metabolic derangement during exercise.
- Conditions
- Metabolism, Inborn Errors, Lipid Metabolism, Inborn Errors, Carbohydrate Metabolism, Inborn Errors, Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
- Trial name
- NCT02635269
- Testing
- Sugar
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sepsis
Lactate Metabolism After an Endotoxin Challenge in Healthy Humans
Sepsis is characterized by hyperlactatemia, the severity of which is proportionate with sepsis severity. The pathophysiological mechanisms (increased lactate production vs decreased lactate utilization; tissues involved in…
- Trial name
- NCT01647997
- Testing
- bacterial endotoxin challenge
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Gingivitis
Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use
The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.
- Trial name
- NCT06770114
- Testing
- Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Sportive Performance, Caffeine
Effects of Caffeine on Upper Extremity Performance
It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue.
- Trial name
- NCT05916352
- Testing
- Caffeine Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Smoking
User Acceptability of a Nicotine Lactate Delivery System (P3L)
This study will provide an initial assessment of the acceptability of the Nicotine Lactate Delivery System (P3L) after ad libitum use and the ability of combustible cigarette (CC) smokers to use P3L to maintain their customary…
- Trial name
- NCT02643693
- Testing
- P3L, VUSE, CC
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Healthy Elderly Individuals
Investigation of the Effect of Functional Respiratory Muscle Training on Functional Level, Balance and Biochemical Parameters in Elderly Individuals.
The aim of this thesis study is to investigate the effects of functional respiratory muscle training on functional level, balance, postural control and biochemical parameters in elderly individuals.
- Trial name
- NCT06924138
- Testing
- Exercise, Standart therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Hip Replacement Arthroplasty
Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate.
- Trial name
- NCT00542516
- Testing
- Hydroxyethyl Starch, Ringer's lactate
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Critical Illness, D-Lactate
Diagnostic And Prognostic Value Of D-Lactate And Scube-1 Levels In Critically Ill Patients
The investigators aimed to investigate the diagnostic and prognostic levels of D-Lactate and SCUBE-1 in critically ill patients being admitted to the emergency department.
- Conditions
- Critical Illness, D-Lactate, SCUBE-1
- Trial name
- NCT06704438
- Testing
- D-Lactate
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital