Clinical trials: Language Disorder
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
EEG
Behavioural and Physiological Measures of Young Students With Dyslexia
The proposed is reading intervention study to track neural changes in the brain. Students with dyslexia will participate in a reading study.
- Trial name
- NCT05376696
- Testing
- Set For Variability, Current Best Practices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Alzheimer Disease, Preclinical Alzheimer's Disease
Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - PAST Extension
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech can detect amyloid-specific cognitive impairment in early stage Alzheimer's disease, based on…
- Conditions
- Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes)
- Trial name
- AMYPRED-PAST (NCT04851496)
- Where
- 4 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Aphasia, Apraxia of Speech
Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Speaking in unison with another person is included as a part of many treatment approaches for aphasia. It is not well understood why and how this technique works.
- Trial name
- NCT05248295
- Testing
- Unison speech (vs. solo), Metrical timing (vs. conversational)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Stroke, Aphasia
Enhance of Language Learning With Neurostimulation
The purpose of this study is to test the effect of transcranial direct current stimulation over the motor cortex of the language dominant hemisphere on language learning in healthy subjects and stroke patients with aphasia.
- Conditions
- Stroke, Aphasia, Aging
- Trial name
- NCT00854893
- Testing
- transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dysarthria, Intelligibility, Speech
Perceptual Training to Improve Listeners' Ability to Understand Speech Produced by Individuals With Dysarthria
There exist very few effective treatments that ease the intelligibility burden of dysarthria. Perceptual training offers a promising avenue for improving intelligibility of dysarthric speech by offsetting the communicative burden…
- Trial name
- NCT04897711
- Testing
- Perceptual Training
- Where
- 2 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Utah State University
Subcortical Aphasia, Ischemic Stroke
Language Functional Reorganization in Subcortical Infarction Patients
Post stroke aphasia (PSA) is one of the most frequently happened deficiency of stoke, affecting speaking,comprehension, writing and reading of language.
- Trial name
- NCT03668132
- Testing
- ischemic brain damage
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD)
Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases
Neurodegenerative diseases, including frontotemporal lobar degeneration (FTLD) spectrum syndromes, are characterized by the accumulation of insoluble protein aggregates in the central nervous system.
- Conditions
- Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD), Primary Progressive Aphasia(PPA), Progressive Supranuclear Palsy(PSP)
- Trial name
- NCT07567664
- Testing
- 3 Tesla MRI without contrast medium, Blood sample for genetic analysis, Cerebrospinal fluid sampling (CSF)
- Where
- Italy
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Marijuana Use
Computer-Mediated Versus Face-to-Face Motivational-Type Interviews
This study looks at whether in-person and computer-based motivational type interviews lead to the same kind of language and behavior change in young adults when they talk about their marijuana use.
- Trial name
- NCT06945471
- Testing
- 1) Face-to-face, and 2) Computer-mediated motivational type interviews
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Type 2 Diabetes Mellitus, Hypertension
LLM-Assisted Diabetes and Hypertension Management by Village Doctors
This is a prospective, assessor-blinded, randomized controlled study designed to evaluate whether large language model (LLM)-assisted decision support can improve village doctors' abilities in the comprehensive management of…
- Trial name
- NCT07678658
- Testing
- LLM
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu Taizhou People's Hospital
Hearing Loss, Screening
Adaptation of Pediatric Speech Audiometry Tests Into Other Languages
The objective of this study was to offer a comprehensive framework for the adaptation of speech audiometric tests into other languages.
- Trial name
- NCT07156825
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Language Development
Language Development in Preterm Children
This research investigates the ways in which preterm birth affects how very young children learn to speak and understand language, and how older children gain efficiency in language processing.
- Trial name
- NCT01599780
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Aphasia, Stroke
ReadMap: Reading in Stroke Alexia and Typical Aging
Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- ReadMap (NCT06700005)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Autism Spectrum Disorder
Training Early Social Language in Autism
The aim of the study is to determine whether a targeted behavioral intervention can lead to both changes in early communication skills and in neural responses in toddlers and preschoolers with autism.
- Trial name
- TESLA (NCT03427138)
- Testing
- Jasper, Parent Education
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Language Disorders
China Obstetrics and Gynecology Journal Club
The purpose of this study is to determine if an intensive journal club based on articles and materials provided on the journal Obstetrics and Gynecology Website improves written and spoken comprehension of medical English in a…
- Trial name
- COG-JOCS (NCT01844609)
- Testing
- Self Study Journal Club, Intensive Journal Club
- Where
- 2 sites in United States, China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Primary Progressive Aphasia, Semantic Dementia
Treatment for Speech and Language in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT04881617
- Testing
- Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Breast Cancer
Large Language Models to Aid Gynecological Oncology Treatment
This trial aims to assess the impact of providing medical students with access to large language models, in comparison to treatment guideline pdfs, on treatment concordance with a conventional multidisciplinary tumor board
- Trial name
- EASING (NCT06865534)
- Testing
- Local language model, Guideline pdf
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg