Clinical trials: Laparoscopic/Minimally Invasive Colorectal Surgery
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Pain
Which Trocar Access Site Should We Use in Laparoscopic Appendectomy?
Open appendectomy has been used in the treatment of appendicitis, which is among the most common emergency pathologies worldwide, since the end of the 19th century.
- Trial name
- NCT05311995
- Testing
- Only different trocar sites
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Inonu University
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Colon Neoplasms
Multicenter Single-port Colectomy RCT
This clinical trial is going to compare the single-port and multi-port laparoscopic colectomy for colon cancer treatment, in terms of safety, efficacy, and cost.
- Trial name
- SIMPLE (NCT01480128)
- Testing
- Single-port, Multi-port
- Where
- South Korea
- Sponsor
- The Catholic University of Korea
Colorectal Neoplasms, Incisional Hernia
AP-NOSES: A Prospective Multicentre Registry of Natural Orifice Specimen Extraction in Minimally Invasive Colorectal Surgery
Natural orifice specimen extraction (NOSE) is a minimally invasive colorectal surgical technique in which the surgical specimen is removed through a natural orifice, including transanal or transvaginal routes, thereby avoiding an…
- Trial name
- AP-NOSES (NCT07615036)
- Testing
- Natural Orifice Specimen Extraction, Transabdominal Specimen Extraction
- Where
- Singapore
- Volunteers
- 800 people
- Sponsor
- Singapore General Hospital
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Colon Cancer, Colon Neoplasm
Long-term Results in Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy
Advantages of laparoscopic right colectomy with intracorporeal anastomosis (IA) compared to extracorporeal anastomosis (EA) are widely studied.
- Conditions
- Colon Cancer, Colon Neoplasm, Malignant Neoplasm, Colon Neoplasia
- Trial name
- NCT05446558
- Testing
- Intracorporeal anastomosis, Extracorporeal anastomosis
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Colorectal Cancer
Comparison of NOSES and Conventional Laparoscopic Surgery in Colorectal Cancer
Radical surgery for rectal cancer has evolved from the initial concept of total mesorctal excision (TME) to the wide application of laparoscopic surgery in the radical treatment of rectal cancer.
- Trial name
- NCT04559087
- Testing
- Laparoscopic Surgery
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zunyi Medical College
Colorectal Cancer
Minimally Invasive Simultaneous Colorectal and Liver Surgery
Up to 25% of newly diagnosed patients with colorectal cancer (CRC) have liver metastases (LM). Simultaneous colorectal and hepatic resection has been proven to be a safe and effective approach in dealing with metastatic…
- Trial name
- NCT03551470
- Testing
- Robotic one-stage colorectal and liver resection
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Rectal Cancer
A Prospective Feasibility Study for TAMIS
Most recently, the Transanal Minimally Invasive Surgery (TAMIS) approach combined with single-port technology has allowed that pelvic surgery can be laparoendocopically performed from both its abdominal and perineal…
- Trial name
- TAMIS (NCT02626728)
- Testing
- laparoscopic assisted transanal surgery (TAMIS)
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Hvidovre University Hospital
Pain, Postoperative, Pain, Abdominal
Optimal Peripheral Nerve Block After Minimally Invasive Colon Surgery
The purpose of the trial is to identify the "most simple non-inferior of three different methods", placebo, laparoscopic assisted transverse abdominal plane block (L-TAP) and ultrasound guided TAP block (US-TAP), using…
- Conditions
- Pain, Postoperative, Pain, Abdominal, Analgesia, Surgery
- Trial name
- OPMICS (NCT04311099)
- Testing
- Active drug, Injection of Ropivacaine - Ultrasound-guided transverse abdominal plane block, Injection of Ropivacaine - Laparoscopic assisted transverse abdominal plane block
- Where
- 5 sites in Denmark
- Volunteers
- 360 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Rectal Carcinoma
Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer
The purpose of this study is to evaluate the safety and oncological feasibility of robot-assisted surgery for mid/low rectal carcinoma compared with laparoscopic surgery.
- Trial name
- REAL (NCT02817126)
- Testing
- Robot-assisted resection, Laparoscopic resection
- Where
- 11 sites in China
- Volunteers
- 1,240 people
- Sponsor
- Fudan University
Prostate Cancer, Rectal Cancer
Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS)
Despite the high volumes, advanced minimally invasive surgery is non-standardised and variations often occur in surgical technique, performance, delivery, team communication, and surgical approach.
- Trial name
- VAMIS (NCT05279287)
- Testing
- Video and kinematic data recording of minimally invasive surgical procedure
- Where
- 5 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Griffin Institute
Rectal Neoplasms
Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasias
A multicenter non-inferiority randomized clinical trial to compare Endoscopic treatment (ESD) and Minimally Invasive Laparoscopic Local Surgical Treatment (TAMIS or TEO) for early rectal neoplastic lesions (adenoma \& T1CRC)…
- Trial name
- DSETAMIS2018 (NCT03959839)
- Testing
- ESD, TAMIS, TEO
- Where
- 3 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Dr. Alberto Herreros de Tejada Echanojáuregui
Colonic Neoplasms, Laparoscopy
ERAS in Laparoscopic Surgery for Colorectal Cancer: Risk Factors for Delayed Recovery
Although there is evidence for reducing complication rate and improving recovery after the implementation of Enhanced Recovery After Surgery (ERAS) protocols into colorectal surgery, most published papers include patients…
- Conditions
- Colonic Neoplasms, Laparoscopy, Perioperative Care
- Trial name
- NCT02527967
- Where
- Poland
- Volunteers
- 143 people
- Sponsor
- Jagiellonian University
Laparoscopic/Minimally Invasive Colorectal Surgery
A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery
The primary purpose of this study was to determine the optimal dose of ASP5354 for ureter visualization in participants undergoing laparoscopic/minimally invasive colorectal surgery This study also investigated the safety…
- Trial name
- NCT04238481
- Testing
- Pudexacianinium chloride
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Astellas Pharma Inc
Rectal Cancer
Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer
This study is designed to assess the surgical, oncological and functional outcome of either the laparoscopic or trans-anal TME in management of mid and low rectal cancer.
- Trial name
- MansTaTME (NCT03242187)
- Testing
- Trans-anal total mesorectal excision(TaTME), Lap. TME
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Minimally Invasive Surgical Procedures, Colon Cancer Patients
Pain Evaluation Across Robotic and Laparoscopic Surgery for Colorectal Procedures
Minimally invasive surgery for colorectal conditions, such as laparoscopic or robotic surgery, has been shown to offer benefits over traditional open surgery.
- Trial name
- PEARL (NCT07431892)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Colorectal Disorders, Surgery
Transverse Abdominus Plane Block Study
Study the effect of laparoscopic guided TAP block on opioid consumption and associated costs using a mixture of dexmedetomidine, dexamethasone, and ropivacaine versus Liposomal bupivacaine (Exparel®) in patients who undergo…
- Trial name
- TAP (NCT05216055)
- Testing
- Ropivacaine, Dexmedetomidine, Dexamethasone sodium phosphate, Normal saline, Liposomal bupivacaine
- Sponsor
- University of Colorado, Denver