Clinical trials: Laparoscopic Appendectomy
Hemodynamic Response, Acute Appendicitis
Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Hemodynamic Response, Acute Appendicitis, Complication of Treatment, Opioid Consumption
- Trial name
- NCT05238506
- Testing
- Intravenous lidocaine, Normal saline infusion
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Warsaw
Appendicitis, Pregnancy Loss
Laparoscopic Versus Open Appendectomy in Pregnancy
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
- Conditions
- Appendicitis, Pregnancy Loss, Pregnancy Preterm
- Trial name
- NCT05430633
- Testing
- Appendectomy
- Where
- Estonia
- Volunteers
- 109 people
- Sponsor
- North Estonia Medical Centre
Complicated Acute Appendicitis
The Value of Post-operative Antibiotic Therapy After Laparoscopic Appendectomy for Complicated Acute Appendicitis (Other Than for Generalized Peritonitis)
Around 30% of appendectomies are performed for complicated acute appendicitis (CAA, i.e. cases with perforated appendicitis, extraluminal fecaliths, abscesses, or local or generalized peritonitis).
- Trial name
- ABAP (NCT03688295)
- Testing
- No antibiotics, Antibiotics
- Where
- France
- Volunteers
- 1,476 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Perforated Appendicitis
Effect of Intraperitoneal Drain Placement on Postoperative Outcomes Following Laparoscopic Appendectomy in Adult Patients With Perforated Appendicitis
Acute appendicitis is the most common acute abdomen, and a small number of patients can progress to perforated appendicitis, which has significantly higher complications than non-perforated appendicitis.
- Trial name
- LADPA (NCT06927765)
- Testing
- No abdominal drain is placed
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Laparoscopic Appendectomy, Pain Management
Comparing N-Acetylcysteine (NAC) Versus Alpha-Lipoic Acid (ALA) as Adjuncts for Postoperative Pain Management After Laparoscopic Appendectomy
Postoperative pain remains a major concern following laparoscopic appendectomy, despite advances in minimally invasive surgery and multimodal analgesia.
- Conditions
- Laparoscopic Appendectomy, Pain Management, Anti Oxidative Stress
- Trial name
- NCT07360379
- Testing
- N Acetyl Cysteine, Alpha-Lipoic Acid (ALA)
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Appendicitis, Surgical Site Infection
Transumbilical Laparoscopic Appendectomy
Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches.
- Trial name
- NCT06177418
- Testing
- Transumbilical laparoscopic appendectomy + Glove finger technique, Standard transumbilical laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Appendicitis
Single Incision Laparoscopic Appendectomy in the Community Utilizing Conventional Instruments
There is a move to "scarless surgery" and this achieved by doing laparoscopic abdominal surgery though a single small umbilical incision.
- Trial name
- NCT00925145
- Testing
- Single Incision Laparoscopic Appendectomy
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Appendicitis
Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
To compare surgical site infection (SSI) rate in patients undergoing laparoscopic appendectomy for acute uncomplicated appendicitis and treated with single dose regime of antibiotics versus group of patients undergoing…
- Trial name
- NCT02404064
- Testing
- cefamezin 1g IV, metronidazole 500 mg IV
- Volunteers
- 288 people
- Sponsor
- HaEmek Medical Center, Israel
Postoperative Pain
Ropivacaine With Clonidine For Pediatric Rectus Sheath Blocks- The Magic Combination
Background: Millions of pediatric patients undergo laparoscopic surgeries every year and many of them suffer significant pain and anxiety.
- Trial name
- NCT02439281
- Testing
- Clonidine, Ropivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mihaela Visoiu
Laparoscopic Appendectomy
A Study to Determine the Effectiveness of Utilizing Intraperitoneal Bupivacaine
The purpose of this research is to determine if spraying a local anesthetic to the cecum after a laparoscopic appendectomy decreases the amount of narcotics (pain medicine) needed after surgery and reduces the time to discharge…
- Trial name
- NCT03004222
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Metro Health, Michigan
Appendicular Mass, Acute Appendicitis
Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular Mass
This study compares two standard treatment approaches for patients presenting with an appendicular mass, an inflammatory lump that forms when the appendix becomes severely inflamed and walled off by surrounding abdominal tissues.
- Conditions
- Appendicular Mass, Acute Appendicitis, Appendiceal Phlegmon, Appendicitis With Periappendicular Abscess
- Trial name
- NCT07837531
- Testing
- Immediate Laparoscopic Appendectomy, Interval Laparoscopic Appendectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Abscess
Oxygen Insufflation To Reduce Postoperative Abscess In Laparoscopic Appendectomy
Oxygen has inherent bactericidal properties. The investigators are testing to see if they can reduce the incidence of postoperative abscesses following laparoscopic appendectomy by insufflating with oxygen at the end of the case.
- Trial name
- AppyO2 (NCT01531413)
- Testing
- Oxygen Insufflation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Chang, Steve S., M.D.
Intraabdominal Abscess, Wound Infection
Appendectomy in Children Performed by Residents in the Era of Laparoscopic Surgery
Introduction: An increasing proportion of childhood appendicitis is treated with laparoscopic appendectomy (LA). The investigators wanted to elucidate the outcome of childhood appendicitis treated primarily by residents in a…
- Trial name
- NCT01657565
- Where
- Denmark
- Volunteers
- 390 people
- Sponsor
- Odense University Hospital
Acute Appendicitis, Appendectomy
RICA (ERAS) Pathway Adherence and Early Discharge Feasibility After Urgent Uncomplicated Appendectomy (APENERAS)
This multicenter, prospective observational study (APENERAS) evaluates adherence to the RICA (ERAS Zaragoza 2022) perioperative care pathway in adults undergoing urgent laparoscopic appendectomy for uncomplicated acute…
- Conditions
- Acute Appendicitis, Appendectomy, Ambulatory Surgery
- Trial name
- APENERAS (NCT07401407)
- Where
- 4 sites in Spain
- Volunteers
- 193 people
- Sponsor
- Hospital Galdakao-Usansolo
Acute Appendicitis
TAP Block for Laparoscopic Appendicectomy in Adults
Laparoscopic (key-hole) appendicectomy is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Trial name
- NCT03252561
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Appendicitis
APPEndicitis and Laparoscopic Criteria; APPEL Study
A diagnostic laparoscopy is frequently used to confirm the diagnosis of appendicitis. However, laparoscopic criteria for determining appendicitis are not defined.
- Trial name
- APPEL (NCT01054417)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- University Medical Center Groningen
Appendicitis
Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Despite growing popularity, practical advantages of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) have yet to be established well in pediatric population.
- Trial name
- PASTA (NCT03106467)
- Testing
- Single-port laparoscopic appendectomy, Three-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Hallym University Medical Center
Appendicitis
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
- Trial name
- HASSEL (NCT07049965)
- Testing
- Suture ligation, Harmonic Scalpel
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Appendicitis, Acute, Appendectomy
Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy is its standard treatment. Although intraoperative adverse events (iAEs) are recognized as an important determinant of surgical…
- Conditions
- Appendicitis, Acute, Appendectomy, Intraoperative Complications, Patient Safety
- Trial name
- PedAppy-iAE (NCT07794618)
- Testing
- Laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ahmet Burak Doğan, MD
Appendicitis
Laparoscopic Versus Open Appendectomy? Let the Patient Decide
This protocol examines choice where it pertains to choosing between two standard methods for appendectomy, laparoscopic or open procedures, and the affect that "cost" of the appendectomy has upon choice.
- Trial name
- NCT01738750
- Testing
- Cost Information Included
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah