Clinical trials: Laparoscopic Colorectal Surgery
Colorectal Cancer, Colon Cancer
Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer
This study is designed to investigate long-term oncologic outcomes of single-incision laparoscopic surgery (SILS) compared to conventional laparoscopic surgery (CLS) for colorectal cancer.
- Conditions
- Colorectal Cancer, Colon Cancer, Rectal Cancer
- Trial name
- CSILS (NCT04527861)
- Testing
- Single-incision Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- 11 sites in China
- Volunteers
- 710 people
- Sponsor
- Ruijin Hospital
Colorectal Surgery, Recovery of Function
Enhanced Recovery Program in Laparoscopic Colorectal Surgery: an Observational Controlled Trial
Background: A few randomized clinical trials and meta-analysis provide evidence for enhanced recovery programs (ERPs) in colorectal surgery.
- Trial name
- NCT04378465
- Testing
- Enhanced Recovery Program (ERP)
- Volunteers
- 200 people
- Sponsor
- University Hospital of Ferrara
Sentinel Lymph Node, Colorectal Cancer
Sentinel Lymph Node (SLN) in Colorectal Carcinoma (CRC) With a Near-infrared (NIR)-Dye
The sentinel lymph node (SLN) procedure is a standard staging technique in several types of cancer. One of the major problems of SLN mapping in colorectal cancer is the lack of an optimal dye and technique for identification of…
- Conditions
- Sentinel Lymph Node, Colorectal Cancer, Metastasis
- Trial name
- NCT02122523
- Testing
- Near-Infrared (NIR) dye Indocyanin Green (ICG)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Amsterdam UMC, location VUmc
Intravenous Lidocaine and Immunity
Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions
This study evaluates the impact of intraoperative intravenous lidocaine administered during laparoscopic colorectal surgery on the intraoperative remifentanil consumption as well as postoperative pain and opioid requirements.
- Trial name
- NCT03410836
- Testing
- intravenous lidocaine (IVL)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Laparoscopic Colorectal Surgery, Postoperative Analgesia
Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
Postoperative nausea and vomiting (PONV) is common after surgery and impede rapid recovery after surgery. Patients who undergo laparoscopic colorectal surgery are more likely to develop PONV due to the pneumoperitoneum…
- Conditions
- Laparoscopic Colorectal Surgery, Postoperative Analgesia, Oliceridine, Morphine
- Trial name
- NCT06411665
- Testing
- Oliceridine, Morphine
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking University First Hospital
Postoperative Ileus, Rectal Cancer
Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer
This is a prospective, randomized, sham-controlled, superiority trial that aimed to investigate the efficacy of electroacupuncture (EA) in reducing the duration of postoperative ileus and hospital stay after laparoscopic total…
- Trial name
- NCT03222557
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 164 people
- Sponsor
- Chinese University of Hong Kong
Postoperative Pain, Analgesia
Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Postoperative Pain, Analgesia, Colorectal Cancer, Surgery
- Trial name
- NCT06881563
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Colorectal Cancer
Trial to Evaluate Laparoscopic Versus Open Surgery in Elderly Colorectal Cancer Patients
Elderly patients have poorer preoperative conditions than younger patients. Therefore, minimally invasive surgery should be an effective treatment method for elderly patients.
- Trial name
- NCT01862562
- Testing
- Open surgery, Laparoscopic surgery
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Shoichi Fujii, MD, PhD
Rectal Cancer, Left Colic Artery Stenosis (Diagnosis)
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation
Brief Summary Background The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA…
- Conditions
- Rectal Cancer, Left Colic Artery Stenosis (Diagnosis), Robotic Assisted Laparoscopic Surgery
- Trial name
- NCT06376227
- Testing
- with or without Left Colic Artery Preservation
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Northern Jiangsu People's Hospital
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Ileus
Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery
Postoperative Ileus is defined as the transient postoperative functional inhibition of propulsive bowel activity. The ethiology of this process can best be described as multifactorial.
- Trial name
- ILEUS (NCT02056405)
- Testing
- Mosapride
- Where
- Argentina
- Volunteers
- 90 people
- Sponsor
- Hospital Italiano de Buenos Aires
Colorectal Cancer
Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer
RATIONALE: Less invasive types of surgery may help reduce the number of side effects and improve recovery. It is not yet known which type of surgery is more effective for colon cancer.
- Trial name
- NCT00002575
- Testing
- conventional surgery, laparoscopic surgery
- Where
- 158 sites in United States, Canada and 1 more
- Volunteers
- 810 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colonic Diseases
Assessing Effectiveness of Laparoscopic Colorectal Surgical Skills
The purpose of this study is to improve the investigators understanding of different training methods in laparoscopic colon surgery.
- Trial name
- NCT01119027
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Laparoscopic Colorectal Surgery
Limb Remote Ischemic Preconditioning for Heart and Intestinal Protection During Laparoscopic Colorectal Surgery
Remote ischaemic preconditioning may confer the cytoprotection in critical organs. The investigators hypothesized that limb remote ischemic preconditioning (RIPC) would reduce heart and gastrointestinal function injury in…
- Trial name
- NCT01832337
- Testing
- Limb remote ischemic preconditioning (LRIP)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fei Li
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Pain
Which Trocar Access Site Should We Use in Laparoscopic Appendectomy?
Open appendectomy has been used in the treatment of appendicitis, which is among the most common emergency pathologies worldwide, since the end of the 19th century.
- Trial name
- NCT05311995
- Testing
- Only different trocar sites
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Inonu University
Postoperative Ileus
Electroacupuncture Versus Fast-track Perioperative Program for Laparoscopic Colorectal Surgery
Background: Our previous study demonstrated that electroacupuncture at Zusanli, Sanyinjiao, Hegu, and Zhigou reduces the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery within a traditional…
- Trial name
- NCT02059603
- Testing
- Electroacupuncture, Fast-track program
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Chinese University of Hong Kong
Ureteric Injury, Surgery
Fluorescent Imaging & Methylene Blue: Ureter Study
The main aim of this project is to assess whether intravenous methylene blue can help identify the ureters during open and laparoscopic (keyhole) surgery.
- Conditions
- Ureteric Injury, Surgery, Surgery--Complications
- Trial name
- NCT03177070
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Colon Cancer
Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer
The purpose of this study is to investigate the preliminary surgical outcomes of laparoscopic right hemicolectomy with transrectal specimen extraction.
- Trial name
- NCT06362902
- Testing
- Laparoscopic right hemicolectomy with transrectal specimen extraction
- Where
- China
- Volunteers
- 37 people
- Sponsor
- National Cancer Center, China
Colorectal Disorders, Incisional Hernia
Incisional Hernia and Adhesion-Related Bowel Obstruction
Despite of technological advances in surgery, incisional hernia and bowel obstruction remain frequent surgical complications. To date, the relationship between these two types of surgery and the occurrence of incisional hernia…
- Conditions
- Colorectal Disorders, Incisional Hernia, Bowel Obstruction
- Trial name
- NCT02116881
- Testing
- Colorectal Surgery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic