Clinical trials: Laparoscopic Fundoplication Procedure
Perioperative Pain Management, Gastreoesophageal Reflux Disease
Intrathecal Analgesia in Laparoscopic Nissen Fundoplication.
Patients planned for laparoscopic Nissen fundoplication or robotic- assisted laparoscopic surgery will receive either intrathecal morphine, intrathecal fentanyl or iv morphine (control).
- Trial name
- NCT07629323
- Testing
- Fentanyl Intrathecal 20ug, NOL-guided intravenous morphine analgesia, Intrathecal Morphine 100ug
- Where
- Sweden
- Volunteers
- 63 people
- Sponsor
- Karlstad Central Hospital
Laparoscopic Nissen Fundoplication
Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication
The purpose of this study is to evaluate the analgesic effects of dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride and their combinations in laparoscopic Nissen fundoplication.
- Trial name
- NCT01558622
- Testing
- dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kavaklıdere Umut Hospital
Gastro -Oesophagal Reflux
Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3-Year Follow-up Study of Randomized Controlled Trial.
Long-term results following laparoscopic and open Nissen fundoplication for gastro-oesophageal reflux will be objectively assessed in a selected population of patients already included in a randomized controlled trial comparing…
- Trial name
- NCT00259961
- Testing
- open fundoplication, laparoscopic fundopliaction
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Extraesophageal Symptoms, Gastroesophageal Reflux Disease (GERD)
A Study on the Effectiveness of Laparoscopic Fundoplication on Extraesophageal Manifestations of Gastroesophageal Reflux Disease (GERD)
Available data regarding the effectiveness of laparoscopic antireflux surgery on extraesophageal symptoms of gastroesophageal reflux disease (GERD) are scarce and mostly controversial.
- Trial name
- NCT01324986
- Testing
- Laparoscopic anti-reflux surgery
- Where
- Austria
- Sponsor
- General Public Hospital Zell am See
Hiatal Hernia Large
Recurrence Rate After Laparoscopic Repair of Large Hiatal Hernia
Patients who underwent laparoscopic repair of large hiatal hernias and anterior fundoplication with mesh are examined for their recurrence rate one year after surgery.
- Trial name
- NCT03025932
- Testing
- repair of giant hiatal hernia with mesh and anterior fundoplication
- Volunteers
- 200 people
- Sponsor
- Prof Urs Zingg
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Gastroesophageal Reflux
Clinical Trial Comparing Open and Laparoscopic Nissen Fundoplication in Children
The purpose of this study is to determine whether short- and long-term outcomes are different between open and laparoscopic Nissen fundoplication performed in children younger than 2 years of age.
- Trial name
- NCT00382850
- Testing
- Nissen fundoplication
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Johns Hopkins University
Duodenogastric Reflux
Laparoscopic Total Fundoplication for Duodenogastroesophageal Reflux
After laparoscopic total fundoplication (LTF) 12-15% of patients have persistent reflux symptoms and 20-25% develop gas-related symptoms.
- Trial name
- NCT01741441
- Testing
- laparoscopic total fundoplication
- Where
- Italy
- Volunteers
- 188 people
- Sponsor
- University of Turin, Italy
Gastroesophageal Reflux Disease (GERD), Gastroesophageal Reflux (GER)
Development of Machine Learning Models to Predict Postoperative GERD Symptom Resolution After Laparoscopic Nissen Fundoplication
This study aims to develop machine learning models to predict postoperative gastroesophageal reflux symptom resolution after laparoscopic Nissen fundoplication using Elastic Net regression and synthetic minority oversampling…
- Trial name
- NCT06862037
- Testing
- Laparoscopic Nissen fundoplication
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Korea University Anam Hospital
Gastroesophageal Reflux
A Randomized Controlled Trial of Laparoscopic Nissen Fundoplication Treatment of Patients With Chronic GERD
LNF is an effective intervention in the management of patients with chronic GERD requiring maintenance therapy. LNF is cost-effective compared with long-term medical therapy.
- Trial name
- NCT00182260
- Testing
- Proton Pump Inhibitors, Laparoscopic Nissen Fundoplication
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- McMaster University
Patients Who Were Scheduled for General and Gynecological Laparoscopic Procedures
Evaluation of the Follow Me Mode of the AutoLap System - A Feasibility Study
The main objectives of this study are to evaluate the performance and ease of use of the Follow me mode of the AutoLap system during general and gynecological laparoscopic procedures.
- Trial name
- NCT02326870
- Testing
- AutoLap
- Where
- 4 sites in Israel, Netherlands
- Volunteers
- 33 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Gastroesophageal Reflux Disease
Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease
The aims of this study are to create a prospective data base to evaluate the long term outcomes of medical and surgical treatment of gastroesophageal reflux disease (GERD); to measure standard outcomes as well as patient derived…
- Trial name
- NCT00260572
- Testing
- Questionnaires to evaluate QOL, Questionnaires to evaluate heartburn and quality of life, Questionnaire to evaluate satisfaction with treatment
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Pittsburgh
Gastroesophageal Reflux Disease, Hiatal Hernia
Necessity of Esophageal Dissection During Laparoscopic Fundoplication
This study compares complete dissection of the tissue around the lower esophagus to no dissection of these tissues during laparoscopic fundoplication in children.
- Trial name
- NCT00287612
- Testing
- Lap. Fundo. with Mobilization of the Esophageal Junction, Lap. Fundo. without Mobilization of the Esophageal Junction
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- Children's Mercy Hospital Kansas City
Patients Scheduled for Hernia Repair, Cholecystectomy, Right Colectomy, Nissen Fundoplication and Sigmoid Resection
Safety and Performance Evaluation of the AutoLap System
The main objectives of this study are to evaluate the safety and performance of the AutoLap system in Laparoscopic Cholecystectomy procedures.
- Trial name
- NCT01828580
- Testing
- active laparoscope positioner (AutoLap)
- Where
- 3 sites in Israel, Italy and 1 more
- Volunteers
- 36 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Hiatal Hernia With Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Fundoplication and Hill-Snow Repair for Hiatus Hernia With Endoscopic Evaluation
The goal of this clinical trial is to compare the clinical efficacy and safety of laparoscopic Nissen fundoplication (LNF) versus laparoscopic Hill-Snow repair (LHS) in the management of patients with congenital hiatus hernia, to…
- Trial name
- NCT07387042
- Testing
- Laparoscopic Hill-Snow repair, Laparoscopic Nissen Fundoplication
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Gastroesophageal Reflux Disease
A Prospective Randomized Trial Comparing Laparoscopic Nissen Against Anterior Partial Fundoplication in Treating Gastroesophageal Reflux Disease Among Chinese Patients
The aim of this study is to compare the effectiveness of laparoscopic Nissen against anterior partial fundoplication in the control of gastroesophageal reflux disease among Chinese patients Study hypothesis Laparoscopic Nissen is…
- Trial name
- NCT00480285
- Testing
- Laparoscopic Nissen Fundoplication, Laparoscopic anterior partial fundoplication
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Laparoscopic Toupet Fundoplication, Radiological Negative
Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive Hiatal Hernia Patients
This study aims to assess the feasibility and effectiveness of laparoscopic toupet fundoplication (LTF) for treating gastroesophageal reflux disease (GERD) symptoms and disease-specific Quality of Life (QoL).
- Conditions
- Laparoscopic Toupet Fundoplication, Radiological Negative, Endoscope, Hiatal Hernia
- Trial name
- NCT06884800
- Testing
- Laparoscopic toupet fundoplication
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Gastroesophageal Reflux
Laparoscopic Nissen Fundoplication Comparing Division Versus Non-Division of Short Gastric Vessels
Recently, total fundoplication followed by laparoscopic esophageal hiatoplasty has been the most common surgical treatment for gastro-esophageal reflux.
- Trial name
- NCT00852098
- Testing
- Lap Nissen fundoplication with division of short gastric vessels, Laparoscopic Nissen fundoplication without division of short gastric vessels
- Where
- 2 sites in Brazil
- Volunteers
- 2 people
- Sponsor
- Federal University of São Paulo
Gastro Esophageal Reflux
GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery
The investigators prospectively studied ninety nine GERD patients following laparoscopic hiatal surgery combined with transoral incisionless fundoplication at two community hospitals.
- Trial name
- GERD (NCT03143608)
- Testing
- Esophyx
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Peter G Mavrelis
Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children
Laparoscopic fundoplication is increasingly performed in paediatric surgery. Many types of fundoplication are performed, each has advantages and disadvantages.
- Trial name
- NCT01027975
- Testing
- laparoscopic Nissen/laparoscopic Thal
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust