Clinical trials: Laparoscopic Hysterectomy
Post Operative Pain, Laparoscopic Hysterectomy
Preoperative Acetazolamide
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain.
- Conditions
- Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
- Trial name
- NCT07101250
- Testing
- Acetazolamide 500 MG Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prisma Health-Upstate
Pain, Acute Post-Operative, Dexmedetomidine
Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological Surgery
The aim of this study is to investigate and compare the effects of a continuous infusion of low-dose esmolol and dexmedetomidine versus placebo on intraoperative and postoperative opioid consumption and analgesic efficacy in…
- Conditions
- Pain, Acute Post-Operative, Dexmedetomidine, Analgesia, Esmolol
- Trial name
- NCT07846722
- Testing
- Esmolol hydrochloride, Dexmedetomidine, Normal (0.9%) saline
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Vasiliki Samartzi
Anesthesia for Laparoscopic Hysterectomy
Epidural Versus General Anesthesia for Laparoscopic Hysterectomy
This randomized controlled study will compare epidural anesthesia with general anesthesia in women undergoing elective laparoscopic hysterectomy.
- Trial name
- EGA-LH (NCT07847801)
- Testing
- epidural anesthesia, General Anesthesia (GA)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sabiha Başarı
Laparoscopic Hysterectomy
Endoscopic Tissue Cutting and Abdominal Extraction Device vs. Conventional Cold Scalpel
The aim of the study is to compare the surgical tissue removal success of the endoscopic tissue cutting device, which was designed by the conductor and developed with the support of TUBITAK-1512 project and for which Turkish and…
- Trial name
- SOLENDO-1 (NCT07226375)
- Testing
- Vaginal tissue morcellation with extraction device, Vaginal tissue morcellation with scalpel
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ege University
Laparoscopic Hysterectomy, Gynecology
Evaluation and Comparison Between General Anesthesia VS Two Types of Combined Anesthesia for Opioid Consumption in Laparoscopic Hysterectomy
The aim of the study is to evaluate and compare general anesthesia VS two types of combined anesthesia in opioid consumption after laparoscopic hysterectomy
- Trial name
- NCT06642649
- Testing
- General Anesthesia (control group), General Anesthesia + Spinal anesthesia combined (local anesthetic, morfine and no fentanyl), General Anesthesia + Spinal anesthesia combined (local anesthetic, morfine and 20 mcg fentanyl)
- Where
- 2 sites in Switzerland
- Volunteers
- 45 people
- Sponsor
- Andrea Saporito
Upper Airway Edema, Postextubation Stridor
Trendelenburg Angle and Upper Airway Ultrasound Findings in Laparoscopic Hysterectomy
This observational study was designed to evaluate whether the Trendelenburg position used during laparoscopic hysterectomy is associated with swelling of the upper airway.
- Conditions
- Upper Airway Edema, Postextubation Stridor, Laparoscopic Hysterectomy
- Trial name
- TAU-LH (NCT07794917)
- Testing
- Trendelenburg positioning during laparoscopic hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir City Hospital
Hysterectomy, Laparoscopic Surgery
Ureterolysis in Laparoscopic Total Hysterectomy: Routine Approach
This randomized controlled trial will compare routine bilateral ureterolysis with selective ureterolysis during total laparoscopic hysterectomy for benign gynecological conditions.
- Trial name
- ULTRA (NCT07774858)
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 35,000 people
- Sponsor
- ClinAmygate
Total Laparoscopic Hysterectomy
Routine Versus Selective Ureterolysis During Total Laparoscopic Hysterectomy for Benign Conditions
To evaluate whether routine ureterolysis during Total Laparoscopic Hysterectomy for benign gynecologic conditions affects operative efficiency and perioperative safety compared with a selective ureterolysis approach.
- Trial name
- NCT07774871
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- ClinAmygate
Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy
Effect of Vulvar Re-Antisepsis Before CO₂ Cystoscopy Performed After Laparoscopic Hysterectomy on Postoperative Urinary Infections
This prospective observational study aims to evaluate whether additional vulvar re-antisepsis before intraoperative cystoscopy reduces the incidence of postoperative urinary tract infections (UTIs) in patients undergoing total…
- Conditions
- Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy, Cystoscopy, Antisepsis
- Trial name
- NCT07232446
- Testing
- Additional Vulvar Re-Antisepsis Before Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Alaattin Karabulut
Laparoscopic Hysterectomy
Zip-Stitch® in Minimally-Invasive Surgery (ZIMS) - Safety & Efficacy in Hysterectomy
The primary objective of this study is to evaluate the safety and efficacy of the Zip-stitch® Vaginal Cuff Closure System. This will be primarily done by measuring the frequency of implant passing following system use.
- Trial name
- ZIMS (NCT05570916)
- Testing
- Zip-stitch(R), Reference suture
- Where
- 5 sites in United States
- Volunteers
- 23 people
- Sponsor
- ZSX Medical LLC
Laparoscopic Hysterectomy
Effect of Trendelenburg Position on Patient State Index
The goal of this observational study is to evaluate whether the Trendelenburg position affects electroencephalography-based depth of anesthesia monitoring and cerebral oxygenation during general anesthesia.
- Trial name
- NCT07467200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Laparoscopic Hysterectomy
Total Laparoscopic Hysterectomy With Prior Uterine Artery Cauterization From the Origin Versus Conventional Laparoscopic Hysterectomy
The main goal of this study is to compare between total Laparoscopic hysterectomy proceeded by Uterine artery cauterization at its origin and conventional total Laparoscopic hysterectomy regarding: bleeding , operative time …
- Trial name
- NCT07601971
- Testing
- Total Laparoscopic hysterectomy with prior Uterine artery cauterization from the origin to arm 1, Conventional Laparoscopic hysterectomy to arm 2, Total Laparoscopic hysterectomy with conventional uterine artery ligation
- Volunteers
- 44 people
- Sponsor
- Kafrelsheikh University
Intertransverse Process Block, Mtapa Block
Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy
This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients…
- Conditions
- Intertransverse Process Block, Mtapa Block, Laparoscopic Hysterectomy, Postoperative Pain
- Trial name
- NCT07599787
- Testing
- Intertransverse Process Block, M-TAPA Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Postoperative Analgesia, Laparoscopic Hysterectomy
Preemptive Analgesia in Laparoscopic Hysterectomy
The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the…
- Trial name
- NCT07401927
- Testing
- Ibuprofen, Parasetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun University
Laparoscopic Hysterectomy
Post Operative Pain After Laparoscopic Hysterectomy Using Airseal® Versus Standard Insufflation System
Airseal® is an insufflation management system for laparoscopic surgery which provides stable pneumoperitoneum, continuous smoke evacuation and valve-free access to the abdominal cavity.
- Trial name
- AIRSEAL (NCT03418402)
- Testing
- Airseal®, Standard insufflator
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Total Laparoscopic Hysterectomy
Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy
This randomized, double-blind, controlled study aims to evaluate the efficacy and safety of Tegileridine or Oxycodone for postoperative analgesia in patients undergoing Total Laparoscopic Hysterectomy（TLH）.
- Trial name
- NCT07326683
- Testing
- Tegileridine (tegileridine fumarate injection, IV), Oxycodone（Oxycodone Hydrochloride Injection，IV）
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Xin Chen
Total Laparoscopic Hysterectomy
Acupuncture for Blood Pressure Fluctuation During Total Laparoscopic Hysterectomy
The goal of this pilot clinical trial is to learn about efficacy of acupuncture about blood pressure fluctuation during total laparoscopic hysterectomy in patients with uterine fibroid.
- Trial name
- ASBP (NCT05720884)
- Testing
- acupuncture
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Ilsan Cha hospital
Total Laparoscopic Hysterectomy, Atelectasis, Postoperative
Effects of Ultrasound-guided Recruitment Manoeuvres on Postoperative Pulmonary Complications in OSA Patients Undergoing Total Laparoscopic Hysterectomy
This study aims to evaluate the lung-protective effects of ultrasound-guided lung recruitment maneuvers in patients with OSA undergoing total laparoscopic hysterectomy and to explore the efficacy of EELV measurement in assessing…
- Trial name
- NCT07362680
- Testing
- the sustained inflation recruitment maneuver, the incremental PEEP recruitment maneuver, the Ultrasound-guided recruitment maneuver
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
ASA Class I/II Patients Scheduled for Surgery Under General Anesthesia, Laparoscopic Hysterectomy
THE EFFECT OF ALVEOLAR RECRUITMENT MANOEUVRE ON INTRAOPERATIVE HAEMODYNAMICS
Alveolar recruitment manoeuvre plays a key role in the prevention of atelectasis. In addition, it affects haemodynamic parameters.
- Trial name
- NCT07299396
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Balikesir University
Laparoscopic Hysterectomy, Magnesium Sulfate
Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases
In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.
- Conditions
- Laparoscopic Hysterectomy, Magnesium Sulfate, General Anesthesia
- Trial name
- MgSO4 (NCT05826119)
- Testing
- magnesium sulfate group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University