Clinical trials: Laparoscopic Liver Resection
Liver Cancer, Colorectal Cancer
The Inflammatory Response to Stress and Angiogenesis in Liver Resection
Patients with resectable liver metastases of colorectal origin will be assigned to laparoscopic liver resection or conventional open liver surgery. Blood samples will be drawn preoperatively and 24 hours after resection.
- Conditions
- Liver Cancer, Colorectal Cancer, Metastatic Cancer, Liver Metastases
- Trial name
- NCT03131778
- Testing
- Liver resection
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Laparoscopic Liver Resection, Vascular Occlusion
Bulldog vs. Cotton Tourniquet in Laparoscopic Hepatectomy for Patients
LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments.
- Conditions
- Laparoscopic Liver Resection, Vascular Occlusion, Tourniquet
- Trial name
- NCT04277065
- Testing
- BULLDOG ,A Useful Vascular Occlusion Tourniquet In Laparoscopic Liver Resection, cotton tourniquet
- Where
- China
- Volunteers
- 88 people
- Sponsor
- hui hou
Colon Cancer, Rectum Cancer
The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum
The following project deals with a Danish multicenter trial that evaluates the value of Laparoscopic Ultrasound examination (LUS) in laparoscopic surgery for colon and rectum cancer (CRC).
- Conditions
- Colon Cancer, Rectum Cancer, Liver Metastases
- Trial name
- NCT02079389
- Testing
- Lap+Lus
- Where
- 4 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- Odense University Hospital
Laparoscopic Hepatectomy
Controlled Low Central Venous Pressure Combined With Hilar Block in Laparoscopic Hepatectomy
Hepatectomy is the preferred method for the treatment of liver tumors. Since the liver is a double blood supply organ, massive hemorrhage during hepatectomy may lead to hemodynamic instability, prolonged portal vein occlusion and…
- Trial name
- NCT03422913
- Testing
- controlled low central venous pressure
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sun Yat-sen University
Quadratus Lumborum Block, Thoracic Paravertebral Block
A Trial Comparing Quadratus Lumborum Block (QLB) and Paravertebral Block (PVTB) for Postoperative Analgesia in Hepatectomy
Pain after hepatectomy can interfere with the patients' recovery and may contribute to developing long term pain. Opioids, e.g. morphine, fentanyl, sufentanil, works well for postoperative analgesia, but have several side effects…
- Conditions
- Quadratus Lumborum Block, Thoracic Paravertebral Block, Postoperative Analgesia, Hepatectomy
- Trial name
- NCT03540537
- Testing
- Patient-controlled intravenous analgesia, Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Nanfang Hospital, Southern Medical University
End Stage Liver Disease, Acute Liver Failure
Robotic vs. Laparoscopic vs. Open Living Donor Hepatectomy
This will be a study to examine the outcomes of open, laparoscopic, and robotic Living Donor Liver Transplantation (LDLT) procedures.
- Conditions
- End Stage Liver Disease, Acute Liver Failure, Acute-On-Chronic Liver Failure, Hepatocellular Carcinoma
- Trial name
- NCT06062706
- Testing
- Donor hepatectomy
- Where
- Saudi Arabia
- Volunteers
- 3,448 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Long-term Effects of Cancer Treatment
A Long-term Survival Analysis of Different Surgical Method in Early Hepatocellular Carcinoma
The investigators established three prospective cohorts of patients with BCLC stage 0-A HCC, based on different surgical approaches (open, laparoscopic and robotic).
- Trial name
- NCT05117047
- Testing
- liver resection
- Where
- China
- Volunteers
- 369 people
- Sponsor
- Chen Xiaoping
Colorectal Cancer, Esophageal Cancer
Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery
Evaluation of the Efficacy and Safety of the Thoracoabdominal Endoscopic Surgery System Produced by Shenzhen Cornerstone Robotics Technology Co., Ltd.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy
- Trial name
- NCT07382635
- Testing
- Robot-assisted surgery
- Volunteers
- 98 people
- Sponsor
- Cornerstone Robotics
Liver Tumor
National Polish Registry of Minimally Invasive Liver Surgery
After the two consensus meetings on laparoscopic liver resection in Louisville (2008) and in Morioka (2014) minimally invasive approach for liver resection was finally widely established in liver surgery practice.
- Trial name
- PL-MILS (NCT05516394)
- Testing
- Laparoscopic liver resection
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Liver Tumor
Intraoperative Blood Loss Under Standard Versus Low Pneumoperitoneum Pressure During Laparoscopic Liver Resection.
Commonly the pressure of about 14 mmHg is applied during laparoscopic liver resection (LLR) with moderate neuromuscular blockade.
- Trial name
- NCT06060899
- Testing
- Pneumoperitoneum 14mmHg, Pneumoperitoneum 10mmHg
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical University of Warsaw
Resectable Simultaneous Colorectal Cancer Liver Metastasis
The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with…
- Trial name
- NCT06550700
- Testing
- laparoscopic hybrid surgery (LHS)
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Changhai Hospital
Laparoscopic Liver Surgery
BReLLS: A Prospective Belgian Registry on Laparoscopic Liver Surgery
Setting up a Prospective Belgian National Registry of patients undergoing minimally invasive liver resections will allow the constitution of a national network able to get updated information on indication and results.
- Trial name
- BReLLS (NCT03175419)
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Ghent
Healthy Donors for Liver Transplantation
Comparison Between Pure Laparoscopic Donor Right Hepatectomy and Convensional Donor Right Hepatectomy
Perioperative clincal outcome between PLDRH and conventional open donor right hepatectomy (ODRH) will be compared retrospectively.
- Trial name
- NCT05040529
- Testing
- pure laparoscopic donor hepatectomy, conventional open donor hepatectomy
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Gangnam Severance Hospital
Liver Surgery
ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection
The international and multicentre ORANGE SEGMENTS - Trial is a prospective, double blinded, randomized controlled study comparing patients undergoing parenchymal preserving resection of postero-superior liver segments (involving…
- Trial name
- NCT03270917
- Testing
- Parenchymal preserving postero-superior liver segment resection
- Where
- 16 sites in Belgium, Italy and 4 more
- Volunteers
- 250 people
- Sponsor
- Maastricht University Medical Center
Hepatolithiasis
Robotic-Assisted Laparoscopic Versus Open Surgery for Complicated Hepatolithiasis
The indication of laparoscopic surgery is mainly for early regional type hepatolithiasis. Open surgery is the traditional treatment method for heptolithiasis.
- Trial name
- NCT03297099
- Testing
- Robot-assisted Laparoscopic operation, open surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southwest Hospital, China
Hepatocellular Carcinoma
Robotic Versus Laparoscopic Liver Resection for Hepatocellular Carcinoma
The objective of the study is to investigate the long-term outcomes of minimally invasive liver surgery (robotic vs laparoscopic) for hepatocellular carcinoma patients of stage BCLC 0-A.
- Trial name
- NCT06496113
- Testing
- Minimally invasive liver resection
- Volunteers
- 196 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Colorectal Cancer
Minimally Invasive Simultaneous Colorectal and Liver Surgery
Up to 25% of newly diagnosed patients with colorectal cancer (CRC) have liver metastases (LM). Simultaneous colorectal and hepatic resection has been proven to be a safe and effective approach in dealing with metastatic…
- Trial name
- NCT03551470
- Testing
- Robotic one-stage colorectal and liver resection
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Hypotension During Surgery
Comparison of General Anesthesia Hemodynamics Between R and P in Patients Undergoing Laparoscopic Hepatectomy
This study is a randomized controlled trial designed to investigate the effects of two anesthetics, remimazolam and propofol, on intraoperative hemodynamics in patients undergoing laparoscopic liver resection.
- Trial name
- NCT06714669
- Testing
- propofol, Remimazolam
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sun Yat-sen University
Ventilator Lung, Liver Cirrhosis
Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy
This randomized controlled study's objective is to find a safer mechanical ventilation strategy to reduce intraoperative bleeding in liver cancer patients undergoing laparoscopic major liver resection.
- Conditions
- Ventilator Lung, Liver Cirrhosis, Hepatocellular Carcinoma, Blood Loss, Surgical
- Trial name
- NCT05490147
- Testing
- conventional tidal volume (tidal volume [ml]= ideal body weight [kg]* 10~12) group, low tidal (tidal volume [ml]= ideal body weight [kg] * 6~8) volume
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Liver Cancer, Liver Metastases
Impact of Minimally Invasive and Open Liver Surgery in Different BMI-classes
Despite the worldwide increase of both obesity and use of minimally invasive liver surgery(MILS), evidence regarding the safety and eventual benefits of MILS in obese patients is scarce.
- Conditions
- Liver Cancer, Liver Metastases, Obesity
- Trial name
- MILSOBES (NCT05475054)
- Testing
- Minimally invasive liver resection
- Where
- Italy
- Volunteers
- 9,963 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero