Clinical trials: Laparoscopic Pancreaticoduodenectomy
Pancreatic Carcinoma, Laparoscopic
Comparing Laparoscopic and Open Surgery for Pancreatic Carcinoma
Background: Pancreatic cancer (PC) is one of the most aggressive malignant neoplasms with poor outcomes. Pancreatoduodenectomy (PD) is the only curative treatment for PC.
- Conditions
- Pancreatic Carcinoma, Laparoscopic, Pancreaticoduodenectomy
- Trial name
- NCT03785743
- Testing
- TLPD Surgery, OPD Surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Ampullary Carcinoma, Duodenal Adenocarcinoma
Modified Single-Incision Plus One-Port Versus Conventional Five-Port Laparoscopic Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas
This multicenter, randomized, controlled, non-inferiority trial will compare modified single-incision plus one-port laparoscopic pancreaticoduodenectomy (mSILPD+1) with conventional five-port laparoscopic pancreaticoduodenectomy…
- Conditions
- Ampullary Carcinoma, Duodenal Adenocarcinoma, Distal Cholangiocarcinoma
- Trial name
- NCT07744087
- Testing
- Modified Single Incision plus one-port Laparoscopic Pancreaticoduodenectomy, Conventional Laparoscopic Pancreaticoduodenectomy
- Where
- 4 sites in China
- Volunteers
- 232 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Functional Recovery, Laparoscopy
Comparison of Functional Recovery Between Laparoscopic and Open Pancreaticoduodenectomy
Laparoscopic surgery has not changed much in safety compared with open surgery through many existing studies, and has become a procedure to help patients' recovery.
- Conditions
- Functional Recovery, Laparoscopy, Periampullary Cancer
- Trial name
- NCT03870698
- Testing
- Laparoscopic group
- Where
- South Korea
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreatic Neoplasms
Textbook Outcome as a Composite Outcome Measure in Laparoscopic Pancreaticoduodenectomy
This is a multicenter, retrospective, observational study. Textbook outcome is a composite outcome measure for surgical quality assessment.
- Trial name
- NCT05616403
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,029 people
- Sponsor
- Tongji Hospital
Laparoscopic Pancreaticoduodenectomy
Establishment and Application of an Artificial Intelligence Algorithm for Automatic Identification of Intraoperative Bleeding During Laparoscopic Pancreaticoduodenectomy
Surgeons will label surgical videos of laparoscopic pancreaticoduodenectomy with bleeding information from multicenter. The labeled surgical video will be used as training material to train the algorithmic model so as to build an…
- Trial name
- NCT06172062
- Testing
- laparoscopic pancreaticoduodenectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinrui Zhu，MD
Resectable Lesions Located in the Pancreatic Head or Periampullary Region
Laparoscopic Pancreatoduodenectomy Versus Open Pancreatoduodenectomy
This is a single, retrospective, real-world study to investigate the surgical outcomes of minimally invasive pancreatoduodenectomy and open pancreatoduodenectomy, with the perioperative characteristics and long-term overall…
- Trial name
- NCT05520606
- Testing
- pancreatoduodenectomy
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Laparoscopic Pancreaticoduodenectomy
Extended Pancreatic Neck Transection Versus Conventional Pancreatic Neck Transection During Laparoscopic Pancreaticoduodenectomy( LPDEXCEPT)
The investigators conduct the clinical randomized controlled trial to evaluate the superiority of extended pancreatic neck transection during laparoscopic pancreaticoduodenectomy (LPD).
- Trial name
- LPDEXCEPT (NCT05808894)
- Testing
- extended pancreatic neck transection during laparoscopic pancreaticoduodenectomy
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Xinrui Zhu，MD
Pancreatic Cancer, Common Bile Duct Diseases
A Multicenter Prospective Randomized Controlled Study of RPD Versus LPD
laparoscopic pancreaticoduodenectomy(LPD) and Robot Pancreaticoduodenectomy (RPD), as two minimally invasive methods of pancreaticoduodenectomy(PD), have obvious advantages over traditional open pancreaticoduodenectomy(OPD) in…
- Conditions
- Pancreatic Cancer, Common Bile Duct Diseases, Periampullary Carcinoma
- Trial name
- NCT05755607
- Testing
- laparoscopic pancreaticoduodenectomy, Robot Pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of University of South China
Pancreas Disease
Implementation and Outcome of Minimally Invasive Pancreatoduodenectomy in Europe:
A planned analysis of outcomes among consecutive patients after MIPD from centers participating in the E-MIPS registry (2019-2021).
- Trial name
- E-MIPS (NCT06135233)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 1,336 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pancreatic Neoplasms, Laparoscopic Pancreaticoduodenectomy
Open Versus Total Laparoscopic Pancreaticoduodenectomy
The goal of this clinical trial is to learn more about Total Laparoscopic pancreaticoduodenectomy ( TLPD ) which is performed for participants with pancreatic tumors using the laparoscope.
- Conditions
- Pancreatic Neoplasms, Laparoscopic Pancreaticoduodenectomy, Whipple Operation
- Trial name
- NCT06661135
- Testing
- TLPD total laparoscopic pancreaticoduodenectomy, OPD open pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Periampullary Carcinoma
Total Laparoscopic vs Open Pancreaticoduodenectomy for the Treatment of Periampullary Adenocarcinomas
Laparoscopic pancreaticoduodenectomy (LPD), a surgical option for nonpancreatic periampullary adenocarcinoma (NPPA), is a complex procedure that has become increasing popular.
- Trial name
- NCT07388082
- Testing
- Conventional open pancreaticoduedectomy, Total laparoscopic pancreaticoduedectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Pancreatic Neoplasms
The Differences of Complications Between LPD(Laparoscopic Pancreaticoduodenectomy) and OPD(Open Pancreaticoduodenectomy)
Main objective: This project intends to design a simulated RCT project and clinically relevant RCT study to target, selecting the study titled "Short-Term outcomes Following Laparoscopic vs Open Pancreaticoduodenectomy in…
- Trial name
- TDCBLAP (NCT06685939)
- Testing
- LPD
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Zhijun Bao
Omental Patch, Laparoscopic Pancreaticoduodenectomy
A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Pancreaticoduodenecotmy(PD) is considered as the standard procedure for peri-amplullary or pancreatic head tumors. Laparoscopic pancreaticoduodenctomy(LPD) has been reported with minimal invasive advantages, such as small…
- Conditions
- Omental Patch, Laparoscopic Pancreaticoduodenectomy, Pancreatic Fistula
- Trial name
- NCT04704882
- Testing
- omental patchwork
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhejiang Provincial People's Hospital
Pancreatoduodenectomy
Application of 2D and 3D Laparoscopy in Laparoscopic Pancreaticoduodenectomy: a Prospective Randomized Clinical Trial
Pancreatic cancer is extremely malignant, with a low sensibility to chemotherapy and radiotherapy, and a poor prognosis. Surgical treatment is very important for pancreatic cancer.
- Trial name
- NCT03754595
- Testing
- 3D Laparoscopic pancreatoduodenectomy, 2D Laparoscopic pancreatoduodenectomy
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Periampullary Adenocarcinoma
Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas
The aim of this study was to evaluate the outcomes of LPD versus OPD in non-pancreatic periampullary adenocarcinoma
- Trial name
- NPPC (NCT05788029)
- Testing
- laparoscopic pancreaticoduodenectomy, open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Tongji Hospital
Periampullary Tumor, Complication
RCT Study on Safety of LPD and OPD in the Treatment of Periampullary Tumors
Pancreaticoduodenectomy (PD) is considered one of the most complex and dangerous procedures in general surgery. This procedure is the preferred surgical procedure for treating tumors around the ampulla.
- Conditions
- Periampullary Tumor, Complication, Death, Survival
- Trial name
- NCT04037982
- Testing
- laparoscopic pancreaticoduodenectomy, Open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Beijing Friendship Hospital
Pancreatic Neoplasms
Single-centre Propensity Score-matched Comparison of Laparoscopic Versus Open Pancreatoduodenectomy
Minimally invasive pancreatoduodenectomy is increasingly performed. However, technical challenges and a perceived higher risk of complications has hindered wide adoption of a minimally invasive approach.
- Trial name
- PSMLOPD (NCT05110573)
- Testing
- pancreatoduodenectomy
- Where
- Belgium
- Volunteers
- 172 people
- Sponsor
- General Hospital Groeninge
Borderline Resectable Pancreatic Cancer
Laparoscopic Versus Open Pancreatoduodenectomy Following Neoadjuvant Chemotherapy for BRPC
The aim of this study is to evaluate the safety and efficacy of laparoscopic versus open pancreatoduodenectomy following neoadjuvant chemotherapy for borderline resectable pancreatic cancer
- Trial name
- NCT04855331
- Testing
- Laparoscopic pancreatoduodenectomy, Open pancreatoduodenectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fudan University
Periampullary Carcinoma Resectable
New Technique of End-to-Side Two-Layered Duct-to-Mucosa Pancreaticojejunostomy With Omental Wrapping and Glue (Glubran 2) During Laparoscopic Whipple Operation
Following pancreaticoduodenectomy, omental flaps around the pancreatic anastomosis and adhesive glue can lower the risk of pancreatic fistula, post-pancreatectomy bleeding, and delayed gastric emptying.
- Trial name
- NCT07333755
- Testing
- Pancreaticojejunostomy without omental patch, Pancreaticojejunostomy with omental patch and glue
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Theodor Bilharz Research Institute
Pancreatic Ductal Adenocarcinoma, Ampullary Carcinoma
Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy
This is a monocentric, prospective, randomized controlled trial comparing the safety and efficacy of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD).
- Conditions
- Pancreatic Ductal Adenocarcinoma, Ampullary Carcinoma, Distal Cholangiocarcinoma, Duodenal Adenocarcinoma
- Trial name
- NCT07328607
- Testing
- Open Pancreaticoduodenectomy, Laparoscopic Pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University