Clinical trials: Laparoscopic Surgery
Type 2 Diabetes Mellitus, Obesity
Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes
There is substantial clinical evidence regarding the safety and efficacy of currently practiced bariatric surgical techniques to improve metabolic control and/or resolve type 2 diabetes (T2DM) in clinically severe obese patients…
- Trial name
- SLIMM-T2D (NCT01073020)
- Testing
- Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Joslin Diabetes Center
Nephrectomy
HYbrid RObotic Surgery in Urology
The HYbrid RObotic Surgery in urology (HYROS) study is an early feasibility clinical investigation of a new medical device under the commercial name of Bitrack System.
- Trial name
- HYROS (NCT05864040)
- Testing
- Bitrack System-assisted laparoscopic radical/simple nephrectomy
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Rob Surgical Systems S.L.
Surgical Conditions
Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients
This is a randomized control trial (RCT) that studies the surgical conditions during moderate and deep neuromuscular blockade in 100 morbidly obese patients receiving elective laparoscopic surgery for bariatric surgery.
- Trial name
- BLISS3 (NCT02553629)
- Testing
- Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 109 people
- Sponsor
- Leiden University Medical Center
Opioid Use, Unspecified, Bariatric Surgery Candidate
Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery
A comparison of post-operative opioid use in laparoscopic bariatric surgery patients receiving opioid or opioid-free anesthesia.
- Conditions
- Opioid Use, Unspecified, Bariatric Surgery Candidate, Anesthesia
- Trial name
- NCT04081545
- Testing
- Opioid Anesthetics, Non Opioid Analgesics
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Christine Oryhan
Hysterectomy
A Trial on Laparoscopic Hysterectomy Versus Robotic Hysterectomy
Robotic technology has been used for laparoscopic hysterectomies for over 10 years. Mayo Clinic Arizona has used robotics in Gynecology for the last 10 years with well over 500 procedures performed.
- Trial name
- NCT00895284
- Testing
- Robotic hysterectomy, Standard Hysterectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Living Donors, Nephrectomy
Conventional Laparoscopic Versus Laparoendoscopic Single Site Donor Nephrectomy in Living Donor Kidney Transplantation
Laparoscopic nephrectomy (removal of the kidney) is the most common procedure for people donating a kidney to be used for living donor kidney transplantation.
- Conditions
- Living Donors, Nephrectomy, Kidney Transplantation, Surgery, Laparoscopic
- Trial name
- NCT01236326
- Testing
- Laparoendoscopic single site donor nephrectomy, Conventional laparoscopic donor nephrectomy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Weill Medical College of Cornell University
Laparoscopic Renal Surgery, Laparoscopy
Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics
The primary objective of the current study is to compare intraoperative respiratory mechanics in patients receiving laparoscopic renal surgery under deep neuromuscular blockade (dNMB) and under moderate neuromuscular blockade…
- Conditions
- Laparoscopic Renal Surgery, Laparoscopy, Muscle Relaxation
- Trial name
- NCT02185339
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Seoul St. Mary's Hospital
Neuromuscular Blockade, Rocuronium
Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety
Muscle relaxants are routinely applied during anesthesia to facilitate endotracheal intubation and to improve surgical working conditions.
- Conditions
- Neuromuscular Blockade, Rocuronium, Anesthetics, Anesthesia Complication
- Trial name
- EURORELAX (NCT04124757)
- Testing
- Deep neuromuscular block
- Where
- 8 sites in France, Italy and 2 more
- Volunteers
- 731 people
- Sponsor
- Leiden University Medical Center
Morbid Obesity, Metabolic Syndrome X
Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Bariatric surgery is the most effective treatment for morbid obesity. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure with known safety and effectiveness.
- Conditions
- Morbid Obesity, Metabolic Syndrome X, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT01806506
- Testing
- Laparoscopic sleeve gastrectomy, Roux-en-Y Gastric Bypass
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Colorectal Cancer
Lymphatic Mapping for Sentinel Node Identification and Analysis
The main objective of this study is to determine whether the first (sentinel) lymph nodes in the drainage pathway of colonic tumour can be detected at the time of surgery using a new technique.
- Trial name
- NCT01662752
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Pain
Intraperitoneal Bupivicaine Infusion Using the On-Q Pain Pump After Laparoscopic Surgery
After Laparoscopic surgery most patients experience some form of mild to moderate pain. The current standard of care is to treat this pain with local anesthetics (numbing medication, that deadens the nerve endings) to the small…
- Trial name
- NCT00533845
- Testing
- On-Q Pain Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maimonides Medical Center
Laparoscopic Hysterectomy
Zip-Stitch® in Minimally-Invasive Surgery (ZIMS) - Safety & Efficacy in Hysterectomy
The primary objective of this study is to evaluate the safety and efficacy of the Zip-stitch® Vaginal Cuff Closure System. This will be primarily done by measuring the frequency of implant passing following system use.
- Trial name
- ZIMS (NCT05570916)
- Testing
- Zip-stitch(R), Reference suture
- Where
- 5 sites in United States
- Volunteers
- 23 people
- Sponsor
- ZSX Medical LLC
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Biliary Colic, Cholecystitis
Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy
The Senhance™ surgical robotic system, previously known as Telelap Alf-X (TransEnterix, Morrisville, NC, USA) has recently become available in the UK.
- Trial name
- NCT03380572
- Testing
- Senhance Assisted Cholecystectomy, Laparoscopic Cholecystectomy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Postoperative Nausea and Vomiting
Transcutaneous Electrical Acupoint Stimulation of P6 to Prevent Postoperation Nausea and Vomiting
The purpose of this study is to access the effect of TEAS of P6 in the prevention of PONV in women scheduled for gynecologic laparoscopic surgery with general anesthesia.
- Trial name
- TEASP6PPONV (NCT02096835)
- Testing
- Transcutaneous electrical acupoint stimulation, Tropisetron, Dexamethasone
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Huashan Hospital
Surgery
EPAD Monitoring of Patients Undergoing Robotic Assisted Laparoscopic Genitourinary Surgery
Participants to be enrolled in this study will have been scheduled to have laparoscopic genitourinary surgery and EPAD monitoring as part of their clinical care intraoperatively.
- Trial name
- NCT03319407
- Testing
- EPAD monitoring system
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
Acute Pain
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery.
- Trial name
- NCT00877799
- Testing
- CR845
- Where
- 12 sites in United States
- Volunteers
- 114 people
- Sponsor
- Cara Therapeutics, Inc.
Obesity
Tylenol Levels in Bariatric Patients
The current study is designed to measure and evaluate the pharmacokinetic profiling of acetaminophen in the young obese patient population.
- Trial name
- NCT02982928
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Nationwide Children's Hospital
Neuromuscular Block, Renal Transplant Donor of Left Kidney
Deep Versus Moderate Muscle Relaxation During Laparoscopic Donor Nephrectomy in Enhancing Postoperative Recovery
Postoperative recovery after live donor nephrectomy (LDN) is largely determined by the consequences of postoperative pain and analgesia consumptions.
- Conditions
- Neuromuscular Block, Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney, Surgery
- Trial name
- RELAX (NCT02838134)
- Testing
- Rocuronium, No additional Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Radboud University Medical Center