Clinical trials: Laparoscopic Surgical Procedures
Colorectal Cancer, Esophageal Cancer
Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery
Evaluation of the Efficacy and Safety of the Thoracoabdominal Endoscopic Surgery System Produced by Shenzhen Cornerstone Robotics Technology Co., Ltd.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy
- Trial name
- NCT07382635
- Testing
- Robot-assisted surgery
- Volunteers
- 98 people
- Sponsor
- Cornerstone Robotics
Stomach Neoplasms
No Antimicrobial Prophylaxis for Laparoscopic Distal Gastrectomy
The aim of this study is to evaluate the feasibility and safety of no use of antimicrobial prophylaxis during laparoscopic distal gastrectomy for gastric carcinoma.
- Trial name
- KSWEET-01 (NCT02200315)
- Testing
- No Antimicrobial prophylaxis
- Where
- 3 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Korean South West East Gastric Surgery Group
Rectal Cancer
ArtiSential® for Rectal Cancer Surgery
This study aimed to assess efficacy of ArtiSential® in reducing laparoscopic rectal cancer surgery duration. We retrospectively reviewed the data of patients who underwent laparoscopic low or ultralow anterior resection for…
- Trial name
- NCT06236282
- Testing
- ArtiSential®
- Where
- South Korea
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Laparoscopic Surgery, Pneumoperitoneum
Low-pressure vs Standard-pressure in Laparoscopic Cholecystectomy
Background. Many studies have demonstrated reduced postoperative pain in patients undergoing lower pneumoperitoneum pressure level during laparoscopic cholecystectomy.
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Cholecystitis; Choledocholithiasis, Quality of Life
- Trial name
- NCT04146090
- Testing
- Low-pressure pneumoperitoneum, Standard pressure pneumoperitoneum
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Endometriosis-Associated Infertility
Pentoxifylline and Endometriosis
To prove efficacy of an immunomodulator called pentoxifylline in the treatment of endometriosis in infertile patients undergoing laparoscopy surgery
- Trial name
- LETS1 (NCT00632697)
- Testing
- pentoxifylline
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
Postoperative Complications, Respiratory Insufficiency
Optimal PEEP for Postoperative Oxygenation and Lung Aeration (ULTRASVENT-2)
The purpose of this multicenter, randomized controlled trial (ULTRASVENT-2) is to evaluate the effect of different positive end-expiratory pressure (PEEP) levels on postoperative oxygenation and lung aeration in adult patients…
- Conditions
- Postoperative Complications, Respiratory Insufficiency, Pulmonary Atelectasis, Positive-End Expiratory Pressure
- Trial name
- ULTRASVENT-2 (NCT07613177)
- Testing
- Intraoperative Positive End-Expiratory Pressure (PEEP) Regulation
- Where
- Russia
- Volunteers
- 360 people
- Sponsor
- Moscow Multidisciplinary Clinical Center "Kommunarka"
Adhesive Small Bowel Obstruction
Comparison of Laparoscopic Surgery Versus Open Surgery in the Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction is a common reason for surgical admission. Most common reason for small bowel obstruction is adhesions, which account up to 70-80 % of small bowel obstructions.
- Trial name
- NCT01867528
- Testing
- Laparoscopic adhesiolysis, Open adhesiolysis
- Where
- 8 sites in Finland, Italy
- Volunteers
- 102 people
- Sponsor
- Helsinki University Central Hospital
Gastric Cancer, Laparoscopic Surgery
Early Jejunostomy Nutrition Minimizes Time to Chemotherapy
Adjuvant chemotherapy (AC) for gastric cancer is known to improve prognosis, and longer time to AC is associated with worse survival.
- Conditions
- Gastric Cancer, Laparoscopic Surgery, Chemotherapy
- Trial name
- NCT01766765
- Testing
- Jejunostomy, Early oral nutrition
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinling Hospital, China
Obese
Mechanical Ventilation in Obese Surgical Patients
The purpose of this study is to evaluate whether an intraoperative positive end-expiratory pressures (PEEP) setting strategy aimed at minimizing the mechanical power delivered to the lungs via transpulmonary pressure improves…
- Trial name
- NCT07774065
- Testing
- Standard PEEP (8 cmH₂O)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Colorectal Carcinoma (CRC), Right Hemicolectomy
The Intraoperative Technical Errors of Robotic vs. Laparoscopic Radical Right Hemiclectomy
Experimental design: This study is a multicenter, prospective, randomized, controlled phase III clinical trial that identifies, classifies, defines, and quantitatively analyzes technical errors between robotic and laparoscopic…
- Trial name
- NCT07138859
- Testing
- Robot assisted radical right hemicolectomy (D3 lymph node dissection), Laparoscopic assisted radical right hemicolectomy (D3 lymph node dissection)
- Where
- China
- Volunteers
- 368 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Laparoscopic Hepatectomy, Laparoscopic Liver Thermal Ablation
Assessment of Augmented Reality in Minimally Invasive Surgery
The objective of this study is to test the technical feasibility of LapAR visualization system for guiding laparoscopic surgeries and to gather clinical feedback on the use of this tool.
- Trial name
- NCT03678220
- Testing
- LapAR
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- IGI Technologies, Inc.
Colorectal Cancer
Multivisceral Radical Resection for Surgical T4b Colorectal Cancer: Propensity Score-matched Study Comparing the the Laparoscopic and Open Approaches
This study attempts to compare safety and long-term oncological outcomes between laparoscopic surgery and open surgery in the treatment of clinical T4b Colorectal cancer.
- Trial name
- C-PelvEx-01 (NCT05707598)
- Testing
- Laparoscopic surgery
- Where
- China
- Volunteers
- 638 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Shoulder Pain, Hiatal Hernia
Pain Relief After Hiatal Hernia Repair Surgery
Referred shoulder pain (pain felt when the problem is actually in a different location) is very common after laparoscopic (small, narrow cut) hernia surgery.
- Trial name
- NCT04936711
- Testing
- Resteck Shiatsu Neck and Back Massager, Marcaine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Norton Thoracic Institute
Peritoneal Carcinomatosis
Peritoneal Carcinomatosis Extent Evaluation: Radiologic, Laparoscopic and Pathologic.
pathologically proved ovarian cancer patients that underwent contrast enhanced abdomino-pelvic CT and diagnostic laparoscopy before cytoreductive surgery (CRS) will be included in the study.
- Trial name
- NCT03798132
- Testing
- laparoscopy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Shimaa Abdalla Ahmed
Ventilator Lung, Liver Cirrhosis
Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy
This randomized controlled study's objective is to find a safer mechanical ventilation strategy to reduce intraoperative bleeding in liver cancer patients undergoing laparoscopic major liver resection.
- Conditions
- Ventilator Lung, Liver Cirrhosis, Hepatocellular Carcinoma, Blood Loss, Surgical
- Trial name
- NCT05490147
- Testing
- conventional tidal volume (tidal volume [ml]= ideal body weight [kg]* 10~12) group, low tidal (tidal volume [ml]= ideal body weight [kg] * 6~8) volume
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Gallstone Disease
Comparing Minilaparotomy and Laparoscopic Cholecystectomy as a Day Surgery Procedure
Minlaparotomy (MC) and laparoscopic cholecystoctomy (LC) are commonly applied surgical techniques for the management of symptomatic gallstone disease and both techiques have shown to be feasible for day surgery.
- Trial name
- NCT01873638
- Testing
- Cholecystectomy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Kuopio University Hospital
Rectosigmoid Adenocarcinoma
Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Cancer
During sigmoid or rectal cancer surgery, dissection of lymphnodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect…
- Trial name
- NCT03557528
- Testing
- Laparoscopic colorectal resection
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Roma La Sapienza
Atelectasis, Postoperative Pulmonary
Driving Pressure-guided PEEP Titration in Robot-assisted Laparoscopic Surgeries
The purpose of this study is to investigate the effect of driving-pressure guided positive end-expiratory pressure (PEEP) titration.
- Trial name
- NCT04327193
- Testing
- Titrated PEEP based on driving pressure, Conventional PEEP
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Oxygen Deficiency
Postoperative SpO₂/FiO₂ in Obese and Non-Obese Patients: Role of STOP-BANG
The aim of this study is to evaluate the effect of the Reverse Trendelenburg position on oxygenation (SpO₂/FiO₂ ratio) in the early postoperative period in patients undergoing laparoscopic surgery.
- Trial name
- NCT07188649
- Testing
- oxygen deficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istinye University
Laparoscopic Surgery
Gasless Single-port Laparoscopic-assisted Radical Resection for Rectal Carcinoma
This project aims to investigate the safety and effectiveness of gasless single-port laparoscopic-assisted radical resection (GSLR) in the treatment of rectal carcinoma.
- Trial name
- NCT03318185
- Testing
- gasless single-port laparoscopic surgery, conventional laparoscopic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
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