Clinical trials: Laparoscopy.
Neuromuscular Block, Renal Transplant Donor of Left Kidney
Deep Versus Moderate Muscle Relaxation During Laparoscopic Donor Nephrectomy in Enhancing Postoperative Recovery
Postoperative recovery after live donor nephrectomy (LDN) is largely determined by the consequences of postoperative pain and analgesia consumptions.
- Conditions
- Neuromuscular Block, Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney, Surgery
- Trial name
- RELAX (NCT02838134)
- Testing
- Rocuronium, No additional Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Radboud University Medical Center
Acupuncture, Postoperative Pain Management
Acupuncture on Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy
To lessen related side effects, opioids are used as needed to treat pain after laparoscopic cholecystectomy (LC). Research into the efficacy of acupuncture as an adjunct treatment for postoperative patients has gained traction.
- Conditions
- Acupuncture, Postoperative Pain Management, Cholecystectomy, Laparoscopic
- Trial name
- NCT07110545
- Testing
- Acupuncture
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Pain, Postoperative
Ketolorac Versus Saline at Laparoscopic Incision Sites
Pain control following surgery is a critical aspect of patient care. Pain at incision sites in laparoscopic surgery contributes to overall pain felt by a patient.
- Trial name
- NCT01374828
- Testing
- Ketolorac
- Where
- United States
- Sponsor
- The Cleveland Clinic
Nausea, Vomiting
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the…
- Trial name
- NCT00835965
- Testing
- Dexamethasone, Aprepitant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Main Line Health
Recurrent Inguinal Hernia
Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty
The study aims at detecting possible differences between an open (Lichtenstein) and a video-assisted (TEP) technique in treating recurrent inguinal hernia.
- Trial name
- NCT00642200
- Testing
- Lichtenstein hernioplasty, Laparoscopic TEP
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Prostate Tumor
Remimazolam Versus Propofol for General Anesthesia Induction in Patients on Renin-angiotensin System Blockers Undergoing Robot-assisted Laparoscopic Prostatectomy
The investigators conduct a random assignment into either the remimazolam group or the propofol group. Depending on the group assignment, either remimazolam (0.2 mg/kg) or propofol (1.0 mg/kg) is administered.
- Trial name
- NCT06093971
- Testing
- remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
GERD
Conventional Nissen Fundoplication Versus Laparoscopic Nissen Fundoplication
This is a long-term follow-up of a prospective randomized trial comparing open and laparoscopic Nissen fundoplication.
- Trial name
- NCT01230944
- Testing
- Laparoscopic Nissen fundoplication, Open Nissen fundoplication
- Where
- Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Pancreatoduodenectomy
Application of 2D and 3D Laparoscopy in Laparoscopic Pancreaticoduodenectomy: a Prospective Randomized Clinical Trial
Pancreatic cancer is extremely malignant, with a low sensibility to chemotherapy and radiotherapy, and a poor prognosis. Surgical treatment is very important for pancreatic cancer.
- Trial name
- NCT03754595
- Testing
- 3D Laparoscopic pancreatoduodenectomy, 2D Laparoscopic pancreatoduodenectomy
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Depressive Symptoms
Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
Esketamine, as a powerful analgesic intravenous anesthetic, has a rapid onset and elimination effect, does not inhibit spontaneous respiration, and can slightly stimulate the circulatory system.
- Trial name
- EDSOP (NCT06199011)
- Testing
- Esketamine hydrochloride, Opioid
- Volunteers
- 400 people
- Sponsor
- The Second Hospital of Anhui Medical University
Laparoscopic Surgery, Pediatrics
Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is an important outcome for the patient; patients generally rate PONV as worse than postoperative pain.
- Conditions
- Laparoscopic Surgery, Pediatrics, Nausea and Vomiting, Postoperative, Antiemetics
- Trial name
- NCT05439798
- Testing
- Ondansetron+Dexamethasone, Palonosetron+Dexamethasone, Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Selcuk University
Malignant or Benign Pathology
Low Impact Laparoscopic in Colorectal Resection - PAROS2
To improve post-operative recovery, the concept of Low Impact Laparoscopy was developed in colo-rectal surgery with associating low-pressure pneumoperitoneum and microlaparoscopic surgery.
- Trial name
- PAROS2 (NCT04742881)
- Testing
- Low pressure + microsurgical instruments, Low pressure + standard instruments
- Where
- 3 sites in France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Bordeaux
Appendicitis Acute, Appendicitis Perforated
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days…
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative
- Trial name
- NCT06948071
- Testing
- Discharge on oral antibiotics
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Bariatric Surgery Candidate
Effects of Alveolar Recruitment Strategies on Arterial Oxygenation and Postoperative Inflammatory Response During Laparoscopic Bariatric Surgery: A Randomised Control Trial.
even though the advancement of ambulatory bariatric surgeries, yet the precise spot of recruitment manoeuvres as a secure and efficient approach to enhance the respiratory efficacy of obese patients is still obscured.
- Trial name
- NCT05960071
- Testing
- protective lung strategy with recruitment manoeuvre (RM) - steady PEEP, protective lung strategy with recruitment manoeuvre (RM) - decreasing PEEP
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Obesity, Morbid, Diabete Type 2
Indocyanine Green Test for Evaluation of Perfusion of Staple Line of the Stomach During Laparoscopic Sleeve Gastrectomy
The investigators present the case of a 40-year-old female underwent laparoscopic sleeve gastrectomy. Intraoperative indocyanine green test was performed
- Conditions
- Obesity, Morbid, Diabete Type 2, Cardiac Disease, Vascular Diseases
- Trial name
- NCT05337644
- Testing
- Indocyanine green solution
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Rectal Prolapse, Procidentia
An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy
Background: Rectal prolapse (RP) is the descent of the upper rectum and is a common problem in the western world. Surgery is the only definite treatment and is preferably performed minimally invasive.
- Trial name
- LaProS (NCT01595412)
- Testing
- Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative
Gastrectomy at Low Pressure Trial - (GALPT)
The study is designed to compare two different insufflation devices during surgery, CONMED AirSeal to Lexicon, during Laparoscopic Sleeve Gastrectomy.
- Trial name
- GALPT (NCT07313930)
- Testing
- AirSeal® Insufflation System (AIS), Lexicon AP 50/30 Insufflator
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- SurgiQuest, Inc.
The Aim of the Study is to Analyze the Incidence of Trocar Site Hernia (TSH), in Orifices Created by Trocars Measuring ≥10 mm in Diameter,
Randomized Prospective Trial on the Occurrence of Laparoscopic Trocar Site Hernias
The investigators perform a simple-blind randomized trial with two groups, one in which all the orifices are closed by suturing the external fascia of the abdominal wall (Group A), and another in which the orifices are left open…
- Conditions
- The Aim of the Study is to Analyze the Incidence of Trocar Site Hernia (TSH), in Orifices Created by Trocars Measuring ≥10 mm in Diameter,, and to Determine Whether Closure of the External Fascial Layer Prevents, TSH and Potential Related Complications.
- Trial name
- NCT01240434
- Testing
- Trocar site closure
- Where
- Spain
- Volunteers
- 195 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Laparoscopic Cholecystectomy
Osmaniye State Hospital"
Objective: It was conducted as a randomized controlled experimental study to determine the effect of progressive relaxation exercise applied after laparoscopic cholecystectomy on postoperative pain, nausea and vomiting.
- Trial name
- OSH (NCT06511271)
- Testing
- relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Osmaniye Korkut Ata University
Hysterectomy, Benign Uterine Diseases
Comparison of TLH and LAVH With Over Than 500g
Since the introduction of total laparoscopic hysterectomy in 1989, laparoscopic gynecologic surgery has undergone many advances.
- Trial name
- NCT03146299
- Testing
- TLH vs LAVH
- Volunteers
- 34 people
- Sponsor
- Hanyang University Seoul Hospital