Clinical trials: Larynx
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acute Phonotrauma
Role of Exercise for Wound Healing in the Larynx
The purpose of this study is to explore quantitatively the hypothesis that "resonant voice," may enhance recovery from acute laryngeal phonotrauma, based on molecular assays from human laryngeal secretions and secondarily…
- Trial name
- NCT01009632
- Testing
- Resonant voice, Voice rest, Spontaneous speech
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypopharyngeal Cancer, Laryngeal Cancer
A Machine Learning-Based Risk Prediction Model for Head and Neck Cancerous Lesions
This study aims to develop and validate a clinical prediction model for the risk of head and neck cancerous lesions using deep learning combined with AI algorithms, based on multi-center clinical data.
- Conditions
- Hypopharyngeal Cancer, Laryngeal Cancer, Head and Neck Cancer
- Trial name
- ML-HNC-Risk (NCT07532538)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Airway Management
Safety and Limitation of the 2nd Generation Laryngeal Mask Airway in the Lithotomy Position: An Obsevational Study
Laryngeal mask airway is used in different types of surgery requiring different position, recommendation was raised regarding the use of LMA in Lithotomy position with pressure controlled mode of ventilation.
- Trial name
- LMA (NCT05920447)
- Testing
- LMA
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Laryngeal Masks
Supraorbital Pressure Versus Jaw Thrust for Assessing the Adequate Depth of Anesthesia for LMA Insertion in Children
BACKGROUND AND OBJECTIVES The purpose of this study is to assess whether the loss of motor response to supraorbital pressure can be an alternative to that of jaw thrust to predict optimal condition for laryngeal mask airway (LMA)…
- Trial name
- NCT02618525
- Testing
- Supraorbital pressure, Jaw thrust maneuver
- Where
- Nepal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Larynx Neoplasms
Concurrent Chemoradiation Versus Surgery With Adjuvant Therapy in Advanced Laryngopharyngeal Cancers
Surgery with post operative radiotherapy (PORT) had been the mainstay of treatment for advanced laryngeal-pharyngeal cancers (ALHC) until the eighth decade of the past century.
- Trial name
- NCT00128817
- Testing
- Concurrent Chemoradiation, Laryngectomy + adjuvant radiotherapy/chemoradiotherapy
- Where
- India
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Voice Disorders
Improving Efficacy of Voice Therapy Concepts Via Telepractice and Mobile App Technology
Due to the COVID-19 pandemic, telepractice has grown rapidly. To date, synchronous telepractice (i.e., in real-time videoconferencing) has been the focus of most research with asynchronous telepractice (i.e.
- Trial name
- NCT05220982
- Testing
- Conversation Training Therapy, Global Voice Prevention and Therapy Model, Modified Conversation Training Therapy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- West Chester University of Pennsylvania
LMA Vs I Gel
Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.
Invistigators study both supraglottic airway devices; the classic LMA and the I GEL mask are satisfactory devices providing high airway leaking pressures.
- Trial name
- NCT03843827
- Testing
- Laryngeal Mask Airway, I gel Airway
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laryngomalacia
Laryngomalacia No Longer An Ambiguity
The purpose of this study is to expose some of the factors that may be associated or predisposing to development of laryngomalacia.
- Trial name
- NCT00972764
- Where
- Kuwait
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Boushahri Clinic Medical Center
Intubating Laryngeal Airway
Evaluation of the Intubating Laryngeal Airway in Children
The Air-Q® intubating laryngeal airway (Air-Q® ILA) is an extraglottic device specifically engineered for use both as a stand-alone laryngeal mask airway (LMA) and as a rescue device or "Plan B" device in the event of a difficult…
- Trial name
- NCT00885911
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Intubation;Difficult
Comparison of Endotracheal Intubation Over the Aintree With Fiberoptic Bronchoskop Via the I-gel and LMA Protector
Investigators aimed to compare the ease of use of the LMA protector and I-gel LMA for tracheal intubation with the Aintree catheter in our study.
- Trial name
- NCT03501602
- Testing
- LMA protector, I-gel LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Vocal Fold Immobility
Intraoperative Laryngeal Electromyography (LEMG) in Children With Vocal Fold Immobility: a Longitudinal Study
The goal of this study is to further study the role of LEMG in accurately predicting the recovery of vocal function as well to study the timing of a change of LEMG activity prior to such return of function.
- Trial name
- NCT00771186
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Laryngeal Dystonia, Spasmodic Dysphonia
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain…
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05216770
- Testing
- Brain imaging, Laryngeal sensory block with topical bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Pediatrics, Fasting Period
Effect of Positive End-expiratory Pressure on Gastic Residual Volume
This study was designed as a prospective observational study.
- Trial name
- NCT06426394
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Dysphagia
Foundations for Prescribing Song-Based Therapies: A Quantitative Comparison of Laryngeal Exercises
SINGS explores the therapeutic potential of song-based exercises for treating dysphagia in geriatric populations. The project aims to compare the effectiveness of song-based tasks with traditional speech-language pathology (SLP)…
- Trial name
- SINGS (NCT07595315)
- Testing
- Dysphagia Treatment Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
General Anesthesia
Ambu AuraGain Laryngeal Mask Airway and I-gel in Children
Children aged below 7 years are randomly assigned to AuraGain Group or I-gel group. After anesthetic induction, AuraGain or I-gel is inserted and mechanical ventilation is started.
- Trial name
- NCT03118245
- Testing
- AuraGain, I-gel
- Where
- South Korea
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Intubation;Difficult
Glottic View in Infants With a Shoulder Roll
This study compares the distance from the operating table to the eye of the laryngoscopist while intubating the trachea with or without a shoulder roll.
- Trial name
- NCT03424070
- Testing
- Shoulder Roll
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Common Cold, Respiratory Tract Infections
The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold
A randomized parallel-group two arm superiority trial with an allocation ratio 1:1, both participants and investigators blinded.
- Trial name
- HelZinki (NCT03309995)
- Testing
- Lozenges
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Gastrointestinal Disorder, Functional, Regurgitation, Gastric
Transition to Infant Formula Feeding on Gastrointestinal Regurgitation (TIGER) Study
To compare the frequency of regurgitation and other digestive outcomes between infants who receive an infant formula based on whole goat milk and an infant formula based on cow milk proteins during the transition period from…
- Conditions
- Gastrointestinal Disorder, Functional, Regurgitation, Gastric, Colic, Infantile, Constipation - Functional
- Trial name
- TIGER (NCT05363553)
- Testing
- Infant formula based on whole goat milk, infant formula based on cow milk proteins
- Where
- Thailand
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Dairy Goat Co-operative (N.Z.) Limited
Postoperative Pain
Postoperative Discomfort After Dental General Anesthesia
The aim of this prospective, randomised, controlled clinical trial was to compare immediate postoperative discomfort, emergence delirium and recovery time of the patients intubated using either laryngeal mask airway or…
- Trial name
- NCT03197753
- Testing
- Laryngeal mask airway, Nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University