Clinical trials: Laser
Orthodontic Appliance Complication
Low Level Laser Therapy Applied in Orthodontic Tooth Movement
Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time.
- Trial name
- NCT05695053
- Testing
- Low Level Laser Therapy
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Myopia
Comparison of Next Generation Laser Techniques of Myopia Correction: iDesign vs. SMILE
The proposed study seeks to compare visual acuity, tomographic outcomes, biomechanical changes and inflammatory profile of normal eyes (matched for age, refraction and corneal thickness) undergoing iDesign and SMILE procedure.
- Trial name
- NCT03001401
- Testing
- iDesign, SMILE
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Narayana Nethralaya
Laser-Induced Scar
Clinical Trial to Assess the Efficacy and Safety of EASYDEW MD REGEN Cream Containing Neopop-S.
The purpose of this clinical study is to evaluate the effect on skin regeneration after applying EasyDew MD Regen Cream containing Neopep-S, a regeneration factor, to patients who have undergone picosure picosure laser skin…
- Trial name
- NCT05982509
- Testing
- EasyDew Regen MD Cream
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eun-ji Kim
Insulin Resistance, Inflammatory Markers
Effectiveness of Low Level Laser Therapy on Insulin Resistance and Inflammatory Biomarkers
It is an interventional study in which 60 women estimated to enroll according to random allocation and assigned into two groups equal.
- Trial name
- NCT04477109
- Testing
- low level laser in addition to diet recommendations
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colorectal Neoplasia, Colorectal Inflammation
Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome
The purpose of this study is to determine whether an association between endomicroscopic pattern and colorectal mucosal microbiome exists.
- Conditions
- Colorectal Neoplasia, Colorectal Inflammation, Hyperplasia, Mucosal Microbiome
- Trial name
- NCT02063919
- Testing
- the mucosal microbiome in the biopsy specimen was analysed
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shandong University
Benign Prostatic Hyperplasia
Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP)
Benign prostatic hyperplasia (BPH) refers to the proliferation of smooth muscle and epithelial cells of the prostate gland. The enlarged gland has the potential to result in lower urinary tract symptoms (LUTS) secondary to either…
- Trial name
- NCT03062111
- Testing
- ProTouch Laser Enucleation of Prostate (LEP), Transurethral Resection of Prostate (TURP)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Boston University
Periodontal Diseases
Photobiomodulation and Platelets Rich in Growth Factors (PRGFs)-Assisted Flap Surgery in Treating Stage III Periodontal Defects
Stage 3 periodontitis is a condition marked by swift and severe destruction of periodontal tissues. To effectively regenerate osseous defects resulting from periodontal disease, it is crucial to leverage the intrinsic…
- Trial name
- NCT06641739
- Testing
- laser assisted SPPF, Platelet Rich Plasma
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypermetropia
Use of the VisuMax Femtosecond Laser Lenticule Removal Procedure for the Correction of Hyperopia
The correction of farsightedness using ReLEx SMILE for hyperopia is focus of this investigation. The objective is to evaluate the safety and effectiveness.
- Trial name
- V1601CI (NCT03431571)
- Testing
- ReLEx SMILE
- Where
- 8 sites in China, Czechia and 4 more
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Enlarged Prostate (BPH), Enlarged Prostate With Lower Urinary Tract Symptoms
Ejaculatory-Sparing HoLEP vs Standard HoLEP
The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.
- Trial name
- NCT07631286
- Testing
- Ejaculatory-sparing (ES-sparing) HoLEP
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Myopia, Astigmatism
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
- Trial name
- NCT05611294
- Testing
- Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Remineralization Potential, Dentin Caries
Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated…
- Trial name
- NCT07065305
- Testing
- Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland, Beautifil II LS
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Rate of Canine Retraction, Root Resorption
The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement
The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine
- Trial name
- NCT06520761
- Testing
- Injectable platelet rich fibrin, Low Level LASER
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Laser Therapy, Rejuvenation
Evaluation of Non-ablative and Fractional Combination Treatment for Improvement in Skin's Appearance
The study is designed to determine the safety, efficacy, patient comfort and patient satisfaction of the combined treatment of Refirme ST and Matrix RF both devices approved under 510k clearances.
- Trial name
- NCT01403597
- Testing
- Refirme ST Applicator and Matrix RF Applicator
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Urethral Stricture, Male
Laser Visual Internal Urethrotomy With Versus Without Paclitaxel Injection
To evaluate the outcome of visual internal urethrotomy in treating urethral strictures in males with a holmium: yttrium-aluminium garnet (YAG) laser versus when combined with intralesional injection of paclitaxel.
- Trial name
- NCT06123520
- Testing
- Ho-YAG Laser Visual internal urethrotomy, Ho-YAG Laser Visual internal urethrotomy combined with intralesional submucosal injection of Paclitaxel
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
Comparison Study on Topical Anesthetic Agents (LMX4 and BLT) Prior to Fractional Skin Resurfacing
The purpose of this research study is to test which topical anesthesia: LMX4 (Lidocaine 4%) or BLT (Benzocaine 20%, Lidocaine 6%, and Tetracaine 4%) is more effective in reducing discomfort during treatment with the Fraxel DUAL…
- Trial name
- NCT01842373
- Testing
- LMX4, BLT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Myopia ≤ -6 Diopters or Myopic Astigmatism ≤ -4 Diopters
Outcomes of a New Trans-epithelial Photorefractive Keratectomy (Streamlight PRK) Compared to Conventional PRK Procedures
Photorefractive keratectomy (PRK) involves mechanical or alcohol assisted debridement of the epithelium that leads to potential basement membrane (BM) injury ,with resultant more significant haze and pain compared to laser…
- Trial name
- NCT04710082
- Testing
- Photorefractive keratectomy (PRK)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Sacroilitis
Efficacy of Extracorporeal Shock Wave Therapy, LASER Therapy and Cryotherapy in Patients Having Sacroiliitis
This research aimed to determine the effect of extracorporeal shock wave therapy, LASER therapy and cryotherapy on PPT, Pain and functional disability in patients having Sacroiliitis.
- Trial name
- NCT06569615
- Testing
- shock wave therapy, LASER Therapy, Cryotherapy
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Najran University
Low Back Pain
Effect of Low Level Laser Versus Interferential Current on Postmenopausal Low Back Pain
This study will be conducted to compare the effect of low-level laser and interferential current on postmenopausal low back pain.
- Trial name
- NCT06586450
- Testing
- Low level laser therapy, Interferential current, Core stability exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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