Clinical trials: Laser
Genitourinary Syndrome of Menopause
Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause
Chronic hypoestrogenism in postmenopausal women significantly impacts the urogenital epithelium, leading to Genitourinary Syndrome of Menopause (GSM) and increasing susceptibility to gynecological infections due to vaginal pH…
- Trial name
- NCT06873971
- Testing
- Topical estrogen therapy based on estriol (E3), Active Er:YAG Laser
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Brain Diseases
Analysis of Brain Tumors Using Matrix Assisted Laser Desorption/Ionization Mass Spectrometry
We are collecting brain tissue specimens and blood samples from patients at Vanderbilt University Medical Center who are undergoing intracranial surgery to remove brain tissue, including brain tumors, tissue from epilepsy surgery…
- Trial name
- NCT00592709
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Stable Angina Pectoris
A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04041206
- Testing
- Laser doppler
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Age-Related Macular Degeneration, Diabetic Maculopathy
Selective RPE Laser Treatment (SRT) for Various Macular Diseases
In this prospective clinical study SRT is performed with various pulse durations at 1.7µs and additionally 200ns to evaluate the different clinical effects of both laser regimens.
- Conditions
- Age-Related Macular Degeneration, Diabetic Maculopathy, Central Serous Chorioretinopathy
- Trial name
- NCT00403884
- Testing
- Selective RPE laser treatment
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
Dental Pulp Exposure
The Effect of Laser Combined With Pulp-capping Agents on Direct Pulp Capping
The purpose of this randomized clinical study was to evaluate the efficiency of Er,Cr:YSGG laser irradiation combined with a resin based tricalcium silicate material and calcium hydroxide (CH) in direct pulp capping for 3 months…
- Trial name
- NCT02487329
- Testing
- Calcium Hydroxide, Er,Cr:YSGG laser + calcium hydroxide, TheraCal LC
- Volunteers
- 60 people
- Sponsor
- Near East University, Turkey
Benign Prostatic Hyperplasia (BPH)
Urodynamic Evaluation of Disobstrucitve Power of Aquablation VS Laser Techniques
in the last decade, lots of attemps have been done to identify new technologies able to reply the efficacy of gold standard technique for treating BPH, but with a better safety profile.
- Trial name
- NCT03846700
- Testing
- aquablation, holep, pvp
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bari
Scars
1540nm Non Ablative Fractional Laser Treatment of Scars
Scars are a frequent reason of consultation in a dermatological clinic. Their cosmetic aspect can play a key role in patient satisfaction and self-image.
- Trial name
- NCT01056211
- Testing
- laser treatment, treatment without laser
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ghent
Gingival Recession, Generalized
ASSESSMENT OF CLINICAL PARAMETERS AND LASER DOPPLER FLOWMETRY FOR THE TREATMENT OF MULTIPLE GENGIVAL RECESSIONS WITH TWO TYPES OF SUBEPITELIAL CONNECTIVE GRAFT: RANDOMIZED CLINICAL STUDY
Subepithelial connective tissue graft (SCTG) is considered the gold standard treatment for root coverage in Miller Class I and II single gingival recession.
- Trial name
- NCT03207971
- Testing
- Root coverage treatment with subepithelial connective tissue graft
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Acute Central Serous Chorioretinopathy
Treatment Trial for Acute Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a relatively frequent eye disease in younger patients. It is characterized by serous detachment of the neurosensory retina with or without serous detachment of the retinal pigment…
- Trial name
- NCT02784665
- Testing
- 577-MPL, 577-TL
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Jin Chen-jin
Scarring Alopecia, Androgenetic Alopecia
1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia
Single-center, open-label, baseline-controlled, pilot study evaluating the use of a Nonablative 1470 nm laser for the treatment of androgenetic alopecia and scarring alopecia.
- Trial name
- NCT05460611
- Testing
- Sciton HALO 1470nm Non-ablative laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Rosacea
Comparative Study of Low-Energy 1064nm Laser and DPL in Rosacea Treatment
Rosacea is a common skin disease characterized by transient flushing or persistent erythema and vasodilation symptoms on the face. In more severe cases, papules and pustules may appear in the central part of the face.
- Trial name
- DPL (NCT06915636)
- Testing
- DPL
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Glaucoma
Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma
Glaucoma affects 66 million people worldwide and is the leading cause of irreversible blindness, and Primary angle-closure glaucoma (PACG) is a major form of glaucoma in Asia.
- Trial name
- NCT01004900
- Testing
- Selective Laser Trabeculoplasty, Travoprost/ Timolol/ Azopt/ Brimonidine
- Where
- Singapore
- Volunteers
- 90 people
- Sponsor
- Singapore Eye Research Institute
Frontal Fibrosing Alopecia
Facial Papules in Frontal Fibrosing Alopecia (FFA)
The objective is to evaluate the safety and efficacy of the Cutera 1726 nm laser system (also referred to as AviClear) for the treatment of facial papules in frontal fibrosing alopecia (FFA).
- Trial name
- NCT07340671
- Testing
- Cutera® 1726 nm laser system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Acne Scars - Mixed Atrophic and Hypertrophic
The MIRIA Acne Scar Study
This study is being conducted to evaluate the performance and efficacy of the AVAVA MIRIA Laser Skin System treatment on acne scars.
- Trial name
- MIRIA (NCT05597267)
- Testing
- MIRIA Laser
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Apical Periodontitis
Laser-Activated Versus Passive Ultrasonic Irrigation in Endodontic Retreatment
This study will compare three methods of activating the final irrigation solution in reducing living bacteria inside the root canals of teeth that require root canal retreatment because of apical periodontitis, an inflammatory…
- Trial name
- NCT07903285
- Testing
- Photon-Induced Photoacoustic Streaming, Shock Wave Enhanced Emission Photoacoustic Streaming, Passive Ultrasonic Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Inonu University
Diabetic Macular Edema
Micropulse 810 Nanomolar (nm), Diode Laser for Diffuse Diabetic Macular Edema
Objective: To compare micropulse 810nm diode laser photocoagulation versus argon laser photocoagulation for treatment of diabetic macular edema.
- Trial name
- NCT00552435
- Testing
- Laser photocoagulation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Stroke, Spasticity
Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors
Stroke is one of the leading causes of long-term disability worldwide. Many patients who survive a stroke experience muscle stiffness (called spasticity), especially in the ankle and foot muscles, which makes walking difficult…
- Conditions
- Stroke, Spasticity, Plantar Flexors
- Trial name
- LLLT-STROKE (NCT07273591)
- Testing
- Low Level Laser Therapy, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montiha Azeem
IBD (Inflammatory Bowel Disease), IBD
Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD
This study aims to test the overall hypothesis that the membrane tissue binding capacity of cytokines in the biopsied tissue of patients with Inflammatory Bowel Disease (IBD) is predictive of/strongly correlated to clinical…
- Conditions
- IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease
- Trial name
- NCT07121920
- Testing
- Confocal Laser Endomicroscopy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cook Children's Health Care System
Alopecia Areata
Childhood Alopecia Areata Study Using the 308-nm Excimer Laser
Alopecia Areata (AA) is a skin restricted autoimmune disease of the hair follicle, resulting in hair loss of the scalp, and in severe cases of the entire body.
- Trial name
- NCT01736007
- Testing
- 308-nm excimer laser to alopecia patch, Liquid light guide tip on laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Diverticular Disease, Diverticulitis
Confocal Laser Endomicrospy in Colonic Diverticular Disease
Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the…
- Conditions
- Diverticular Disease, Diverticulitis, Diverticula
- Trial name
- NCT04173182
- Testing
- Probe-based confocal laser endomicroscopy evaluation
- Where
- Ecuador
- Volunteers
- 63 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas