Clinical trials: Laser Photocoagulation
Diabetic Macular Edema
Navigation Laser Versus Traditional Laser Photocoagulation for Mild Diabetic Macular Edema
The aim of this study is to evaluate treatment effect and safety of navigation laser photocoagulation for mild diabetic macular edema compared with traditional laser.
- Trial name
- NCT03641144
- Testing
- Navigation laser, Traditional laser
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Proliferative Diabetic Retinopathy
Retinal Laser by Multi-spot Photocoagulator and Driving Eligibility
The purpose of this study is to determine the risk of failing the visual field criteria to hold a driving license following retinal laser treatment delivered with a multi-spot photocoagulator.
- Trial name
- NCT01383772
- Testing
- Pan retinal Photocoagulation
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Diabetic Retinopathy
Green Laser Photocoagulation Study in Proliferative Diabetic Retinopathy
To Demonstrate that indigenous green laser produces similar treatment effect on the retina when compared with already available green laser.
- Trial name
- NCT00355680
- Testing
- Green Laser (Aurolas, Aurolab), Green Laser (Iridex)
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Aurolab
Twin to Twin Transfusion Syndrome
Laser Photocoagulation in Twin to Twin Transfusion Syndrome
Humanitarian use device (HUD): Use of the fetoscopy instrument sets for selective laser photocoagulation in the treatment of Twin to Twin Transfusion Syndrome (TTTS).
- Trial name
- TTTS (NCT02506049)
- Testing
- S-LPC:Selective Laser Photocoagulation
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- University of Tennessee
Vasa Previa, Pregnancy Complications
Fetoscopic Laser Photocoagulation in Management of Vasa Previa
In this research study, the investigators want to learn more about the safety and effectiveness of a fetal surgery, known as fetoscopic laser photocoagulation (FLP), for the treatment of a pregnancy condition called vasa previa…
- Conditions
- Vasa Previa, Pregnancy Complications, Maternal; Procedure, In Utero Procedure Affecting Fetus or Newborn
- Trial name
- FLUMEN (NCT06290232)
- Testing
- Fetoscopic Laser Photocoagulation
- Where
- United States
- Sponsor
- Boston Children's Hospital
Macular Edema
Diffuse Diabetic Maculopathy With Intravitreal Triamcinolone or Laser
This study compares the use of intravitreous triamcinolone and laser therapy to treat maculopahty in patients with type 2 diabetes mellitus in a short-tem period of 6 months
- Trial name
- NCT00668239
- Testing
- intravitreous triamcinolone, laser therapy
- Where
- 3 sites in Brazil
- Volunteers
- 14 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetic Retinopathy
Early Laser Treatment for Diabetic Eye Disease in China : A Pilot Randomized Trial
To compare immediate laser pan-retinal photocoagulation (PRP) treatment of severe or very severe non proliferative diabetic retinopathy (NPDR) stage versus deferral of treatment until the appearance of any proliferative diabetic…
- Trial name
- NCT02956759
- Testing
- Pan-retinal photocoagulation laser treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Diabetic Macula Edema
To Compare Anti-VEGF Monotherapy With Anti-VEGF and EPM Grid Laser Combination Therapy for Diabetic Macular Edema
Objectives: To compare the efficacy of monotherapy with anti-Vascular Endothelial Growth Factor (ranibizumab or bevacizumab) with combined therapy with anti-Vascular Endothelial Growth Factor and end-point-management grid laser…
- Trial name
- END-DME (NCT02462304)
- Testing
- End-Point-Management grid laser, ranibizumab, Bevacizumab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Diabetic Retinopathy, Diabetic Macular Edema
Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation
This study will compare the side effects of two treatments for diabetic macular edema, in which blood vessels in the retina (tissue that lines the back of the eye) become leaky and the retina and macula (the center part of the…
- Conditions
- Diabetic Retinopathy, Diabetic Macular Edema, DME
- Trial name
- NCT00105404
- Testing
- Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Macular Edema
Micropulse 810 Nanomolar (nm), Diode Laser for Diffuse Diabetic Macular Edema
Objective: To compare micropulse 810nm diode laser photocoagulation versus argon laser photocoagulation for treatment of diabetic macular edema.
- Trial name
- NCT00552435
- Testing
- Laser photocoagulation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Diabetic Macular Edema
Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral Nonperfusion
To investigate the role of ranibizumab and angiographically-directed peripheral scatter laser therapy in patients with clinically-significant diabetic macular edema (CSME) and peripheral nonperfusion.
- Trial name
- RaScaL (NCT00815360)
- Testing
- intravitreal injection of ranibizumab, peripheral laser, intravitreal injection of triamcinolone acetonide
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Retina Associates of Florida, P.A.
Diabetic Retinopathy, Retinal Neovascularization
Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy
The purpose of this study is to evaluate the effects of panretinal photocoagulation plus intravitreal ranibizumab for the treatment of patients with high risk proliferative diabetic retinopathy in terms of changes in visual…
- Trial name
- IRaHi (NCT01102946)
- Testing
- Ranibizumab, Panretinal Photocoagulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Diabetic Retinopathy, Macular Edema
Triple Therapy of Pars Plana Vitrectomy and Grid/Focal Laser for Diabetic Macular Edema (DME)
This study is designed to report 3-year result of triple therapy of vitrectomy, intravitreal triamcinolone and macular laser photocoagulation for intractable diabetic macular edema.
- Trial name
- NCT01202461
- Testing
- Triple therapy of vitrectomy, IVTA and grid/focal laser photocoagulation
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Samsung Medical Center
Macular Edema
A Safety and Efficacy Study of Dexamethasone Versus Laser Photocoagulation in Participants With Diabetic Macular Edema
This study will evaluate the safety and efficacy of 700 μg dexamethasone versus laser photocoagulation in participants with diabetic macular edema (DME).
- Trial name
- NCT02121262
- Testing
- Dexamethasone, Laser Photocoagulation
- Where
- 18 sites in China, Philippines
- Volunteers
- 284 people
- Sponsor
- Allergan
Twin to Twin Transfusion Syndrome
Fetoscopic Selective Laser Photocoagulation in Twin-Twin Transfusion Syndrome
This is a study to compare two treatments (amnioreduction vs. selective fetoscopic laser photocoagulation [SFLP]) in patients with severe twin to twin transfusion syndrome.
- Trial name
- NCT00345852
- Testing
- Fetoscopic Selective Laser Photocoagulation
- Where
- 12 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Twin to Twin Transfusion Syndrome
The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses
The purpose of this study is to evaluate the efficacy of KARL STORZ curved fetoscope (11508AAK) and its straight version (11506AAK) for laser photocoagulation of placental anastomoses in patients with an anterior placenta and…
- Trial name
- NCT06084247
- Testing
- Curved KARL STORZ fetoscope, Conventional Scopes
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Jimmy Espinoza
Retinopathy of Prematurity (ROP)
Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy
The purpose of this study is to demonstrate how well aflibercept works in babies with ROP, comparing it with laser therapy. The study also has the objective to demonstrate how safe aflibercept is when used in babies, and describe…
- Trial name
- FIREFLEYE (NCT04004208)
- Testing
- Eylea (Aflibercept, BAY86-5321), Laser photocoagulation
- Where
- 90 sites in Argentina, Austria and 25 more
- Volunteers
- 113 people
- Sponsor
- Bayer
Benign Solitary Solid, Cystic Thyroid Nodules
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
- Trial name
- NCT00150150
- Testing
- Interstitial laser photocoagulation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Diabetic Macular Edema
Intravitreal Bevacizumab and Triamcinolone Associated to Laser Photocoagulation for Diabetic Macular Edema(IBeTA)
Intravitreal triamcinolone has been effective for central macular thickness reduction and concomitant visual acuity improvement in patients with diabetic macular edema (DME).
- Trial name
- IBeTA (NCT00997191)
- Testing
- Laser photocoagulation, Intravitreal triamcinolone, Intravitreal bevacizumab
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- University of Sao Paulo
Diabetic Macular Edema
Micropulse Laser Photocoagulation in Diabetic Macular Edema
To assess the safety and efficacy of 532 nm subthreshold micropulse laser 5 % duty cycle compared with 15 % duty cycle in treatment of diabetic macular edema .
- Trial name
- NCT07266597
- Testing
- micropulse laser photocoagulation
- Volunteers
- 50 people
- Sponsor
- Sohag University