Clinical trials: Laser in Situ Keratomileusis
Corneal Ectasia
Evaluating Risk Factors of Post-LASIK Ectasia
Ectasia after refractive surgery is a relatively rare complication which can lead to sight-threatening complications if not detected and treated in time.
- Trial name
- NCT03708575
- Volunteers
- 25 people
- Sponsor
- Assiut University
Keratomileusis, Laser In Situ, Contrast Sensitivity
Direct Comparison of TG and WFO LASIK
To compare the efficacy to different profiles, direct head-to-head studies had been conducted. In one previous review study revealed that TG LASIK provided patient with better uncorrected visual acuity (UCVA) than WFO LASIK and…
- Trial name
- NCT04919291
- Testing
- Topoguided LASIK, Wavefront optimized LASIK
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Taipei Nobel Eye Clinic
Corneal Epithelium Defect
GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients
GenTeal gel is an artificial tear gel used to lubricate the surface of the eye. This study will evaluate the effect of GenTeal gel on comfort following LASIK surgery.
- Trial name
- NCT00598689
- Testing
- 0.3% hypromellose
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Augusta University
Myopia, Myopic Astigmatism
A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism
The primary objective of this study is to collect safety and effectiveness data for the Technolas Teneo 317 Model 2 excimer laser for LASIK correction in participants with myopia and myopic astigmatism.
- Trial name
- NCT04111757
- Testing
- Technolas® TENEO 317 Model 2
- Where
- 10 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
IntraLase vs Hansatome Flaps in LASIK
This study compared the clinical outcomes between fellow eyes randomized to either IntraLase femtosecond laser-created flaps or Hansatome mechanical keratome-created flaps during wavefront-guided laser in situ keratomileusis.
- Trial name
- NCT00691431
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
A Comparison of PRK and LASIK for Correction of Myopia
The study compares the precision and accuracy of two laser refractive techniques, PRK and LASIK, for correction of nearsightedness between -6 and -8 diopters.
- Trial name
- NCT00404105
- Testing
- PRK, LASIK
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Myopia, Astigmatism
Z8 OCT-controlled 2D vs 3D LASIK
The aim of this study was to test the hypothesis that OCT-guided 110 µm targeted flaps will result in accurate, predictable, and precise thickness flaps, with low complication rates when performed and compared using both 2D and…
- Trial name
- NCT04426175
- Testing
- 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Zentrumsehstarke Hamburg
Myopia
Optical Coherence Pachymetry to Evaluate Central Corneal Ablation Depth in Myopic Femtosecond Laser in Situ Keratomileusis
Prospective study aiming to measure central ablation depth during excimer laser surgery in myopic patients operated with femtosecond laser assisted LASIK with intraoperative OCP, before and after laser ablation.
- Trial name
- PACO (NCT02893644)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Lasik Eye Surgery
Assessment of the Preoperative Risk Factors for the Development of Post-LASIK Ectasia
: Laser-assisted in situ keratomileusis (LASIK) is one of the most widely performed refractive surgeries, offering effective and long-lasting correction for visual refractive errors.
- Trial name
- NCT06806306
- Testing
- LASIK
- Volunteers
- 13 people
- Sponsor
- Al-Azhar University
Refractive Errors
Anxiety-related Fixation Instability During LASIK
Anxiety is common among patients undergoing eye surgery, which is typically performed under topical anesthesia while the patient is awake.
- Trial name
- NCT06148428
- Testing
- Laser in situ keratomileusis (LASIK)
- Where
- Egypt
- Volunteers
- 2,435 people, healthy volunteers welcome
- Sponsor
- Assiut University
Refractive Errors
Changes in Angle Kappa and Corneal Back Elevations After Laser in Situ Keratomileusis in Myopic Astigmatism
Refractive errors and corneal astigmatism are associated with changes in angle kappa and corneal back elevation at the thinnest point in Pentacam.
- Trial name
- NCT06166212
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Anisometropia
Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old
The purpose of this study is to determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct high anisometropia in patients 8 to 15 years old in whom conventional treatments…
- Trial name
- NCT00800774
- Testing
- LASIK
- Where
- Brazil
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Myopia
Comparison of Intralase and Visumax Femtosecond Laser for Laser In Situ Keratomileusis
Emtosecond lasers are used in cutting the flap in LASIK procedures (laser corrective surgery for refractive error). Their use has decreased the incidence of serious complications when compared to the use of…
- Trial name
- NCT01252654
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Refractive Surgery
CONTOURA vs WFO Ablation PRK & LASIK
This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs.
- Trial name
- NCT05037370
- Testing
- Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Dry Eye Syndromes
An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) Therapy
This is an observational, study of dry eye in patients at the consultation visit prior to LASIK surgery. There is no treatment administered or intervention during the study.
- Trial name
- NCT01854905
- Testing
- No Treatment
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Allergan