Clinical trials: Lasers
Benign Pigmented Lesions
Comparison of Picosecond and Q-switched Laser for Benign Pigmented Lesions Treatment
The objective of this study is to evaluate the efficacy and safety of picosecond 532 and 1,064 nanometers laser in the treatment of benign pigmented lesions compared with q-switched 532 and 1,064 nanometers laser.
- Trial name
- NCT02800525
- Testing
- Picosecond laser, Q-switched Nd:YAG laser
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Preterm Newborns
Laser Acupuncture and Pain Management in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation
Prospective study, controlled, randomized, single-center, blinded, which aims to evaluate the effect of laser acupuncture in the treatment of perioperative pain during tracheal suction after patent ductus arteriosus ligation in…
- Trial name
- ELAPPS (NCT02147717)
- Testing
- Laser stimulation, Fake laser stimulation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Proliferative Diabetic Retinopathy
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy
The purpose of this study was to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR).
- Trial name
- CONDOR (NCT04278417)
- Testing
- Brolucizumab 6 mg, Panretinal photocoagulation laser
- Where
- 120 sites in United States, Argentina and 14 more
- Volunteers
- 689 people
- Sponsor
- Novartis Pharmaceuticals
BPH With Urinary Obstruction, Male
Holmium Laser vs Bipolar Enucleation of a Large Volume BPH: a Randomised Controlled Study
To compare bipolar plasmakinetic enucleation versus holmium laser enucleation for management of large BPH.
- Trial name
- BPH (NCT03998150)
- Testing
- Holmium laser enucleation of the prostate, Bipolar plasma kinetic enucleation of the prostate
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Enamel Demineralization
Comparative Assessment of Adhesive PreCoated (APC) Flash-free and Conventional Brackets and the Effects on Enamel Demineralization and Periodontal Health
Adhesive PreCoated (APC) flash-free brackets have been recently introduced, with no need of flash removal step. Evaluation of APC and conventional brackets and their effects on enamel demineralization and periodontal health.
- Trial name
- NCT07752290
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
Safety and Efficacy of MILEP Versus Standard EEP
Endoscopic enucleation of the prostate (EEP) is a standard treatment for benign prostatic hyperplasia (BPH), with modifications such as MiLEP that utilizes smaller instruments.
- Trial name
- MILES (NCT06839768)
- Testing
- Standard endoscopic enucleation of the prostate (EEP), MiLEP
- Where
- Russia
- Volunteers
- 340 people
- Sponsor
- Sechenov University
Telangiectasis
Laser Therapy Versus Electrosurgery For Nasal Telangiectasias
The aim of this study is to compare the efficacy of various treatment options for eliminating nasal telangiectasias. The study will compare the outcome of treating nasal telangiectasias with the following; no treatment (control…
- Trial name
- NCT02090517
- Testing
- Pulsed Dye Laser, Long Pulsed Alexandrite Laser, Pulsed Dye Laser Plus Nd:YAG Laser
- Where
- United States
- Sponsor
- University of California, Davis
Biological Dressings
Clinical Efficacy of Bovine Freeze-dried Amniotic Membrane on Wound Healing in Laser Treatment
Bovine amniotic membrane may show better efficacy than hydrocolloid dressing.
- Trial name
- NCT01895374
- Testing
- laser treatments, amniotic membrane application, hydrocolloid application
- Where
- South Korea
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Melasma
Tranexamic Acid vs. Combination With Fractional Carbon Dioxide Laser in Melasma
The objective of this study is to assess and compare the efficacy of tranexamic acid intradermal microinjection alone versus its combination with low power fractional CO2 laser in a sequential pattern.
- Trial name
- NCT03899233
- Testing
- Fractional CO2 laser, Tranexamic acid intradermal microinjections
- Volunteers
- 25 people
- Sponsor
- Cairo University
Diabetic Foot Ulcer
Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds
This is a randomized, double blind, placebo-controlled study to evaluate the safety of the low level laser MC-8XL device treatment in subjects with an unsuccessfully treated Diabetic Foot Ulcer (DFU) that has been present for at…
- Trial name
- NCT03204149
- Testing
- MC-8XL low level laser device and Standard wound care
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Medical Coherence LLC
Diabetes Mellitus Non-insulin-dependent
Effects of Low Power Laser Therapy on Muscle Performance Isokinetic Pre-exercise in Individuals With Diabetes Mellitus Type II
The low level laser therapy is able to improve immediately and long term (after 4 weeks of treatment, 3 days per week resulting in 12 applications of low level laser therapy) isokinetic muscle performance of the quadriceps…
- Trial name
- NCT01925443
- Testing
- Low level laser therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Obesity
Effect of Laser Acupuncture on Obesity
Background: Obesity-related diseases have a profound economic impact on health care systems. Laser acupuncture has been shown to have beneficial effects on obesity.
- Trial name
- NCT02167308
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Chang Gung Memorial Hospital
Clinically Significant Macular Edema
Clinical Efficacy of Bevacizumab Combined With Navigated Laser in Patients With Clinically Significant Macula Edema
Asses efficacy of navigated laser in reducing the number of anti-VEGF injections as a prospective study using Bevacizumab.
- Trial name
- NCT02032238
- Testing
- laser photocoagulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- OD-OS GmbH
Vulvar Dysplasia, Vaginal Dysplasia
A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia
1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias 2.
- Trial name
- NCT00394758
- Testing
- CO2 laser surgery, ultrasonic surgical aspiration
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University Hospitals Cleveland Medical Center
Urothelial Carcinoma, Urinary Bladder Cancer
Multimodal Spectroscopy to Detect Urothelial Cancer in Urine
To facilitate the follow-up of urothelial tumors and also make them more tolerable and less invasive for patients, there is a minimally invasive and easy to perform examination which is urinary cytology on 3 samples.
- Conditions
- Urothelial Carcinoma, Urinary Bladder Cancer, Urinary Tract Cancer
- Trial name
- NCT04718948
- Testing
- Urinary Multimodal Fiber Optic Spectroscopy, Urine Cytology, Surgery
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Florence
Knee Osteoarthritis
Combined Effect of Laser Acupuncture and Electroacupuncture in Knee Osteoarthritis Patients
Background: Knee osteoarthritis (KOA) is a common degenerative joint disorder affected 250 million people globally. It can not only result in disability, but also associated with cardiovascular disease and mortality.
- Trial name
- NCT04188925
- Testing
- Laser Acupuncture
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Retinopathy of Prematurity
A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP
This randomized clinical trial will compare retinal outcomes with low-dose intravitreous bevacizumab (0.063 mg) versus laser photocoagulation as treatment for infants with type 1 retinopathy of prematurity (ROP).
- Trial name
- ROP3 (NCT04634604)
- Testing
- Bevacizumab, Laser
- Where
- 35 sites in United States, Canada
- Volunteers
- 16 people
- Sponsor
- Jaeb Center for Health Research
Stickler Syndrome Type 1, Stickler Syndrome Type 2
Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)
The goal of this clinical trial is to prospectively document to what extent the OSC/SS prophylactic laser retinopexy procedure works to prevent retinal detachment in SS in children and adults.
- Trial name
- OSC/SS (NCT07146516)
- Testing
- Prophylactic (non-invasive) Laser Retinopexy
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Helen Keller Eye Research Foundation
Varicose Veins of Lower Limb
Ongoing Registry of Treatment of Chronic Venous Diseases
Ongoing registration of patients with varicose veins disease treated by means of conventional surgery, endovenous thermal ablations, sclerotherapy, non-tumescent non-thermal methods
- Trial name
- RRT CVD (NCT03035747)
- Testing
- conventional surgery, endovenous laser ablation, sclerotherapy
- Where
- Russia
- Volunteers
- 5,000 people
- Sponsor
- Medalp Private Surgery Clinic
Oral Glucose Tolerance Test
Non-invasive Glucose Measurement Using Laser Technology
This study is to evaluate the capability of Raman spectroscopy as a non-invasive method for monitoring concentrations of glucose by illuminating a small spot on the skin, collecting and analyzing the return light.
- Trial name
- (Raman) (NCT03276949)
- Testing
- Blood glucose measurement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
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