Clinical trials: Lasik Eye Surgery
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ametropia
Prospective Study Evaluating Dry Eye in Patients Operated on for Ametropia by LASIK Surgery and Treated With REPADROP
LASIK is a refractive surgery technique widely used in France. Postoperatively, the classic treatment after LASIK consists of instilling drops to reduce dry eyes.
- Trial name
- PREPADROP (NCT04654455)
- Testing
- Describe the evolution of dry eye between 1 month and 3 months post-LASIK
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Myopia, Myopic Astigmatism
A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism
The primary objective of this study is to collect safety and effectiveness data for the Technolas Teneo 317 Model 2 excimer laser for LASIK correction in participants with myopia and myopic astigmatism.
- Trial name
- NCT04111757
- Testing
- Technolas® TENEO 317 Model 2
- Where
- 10 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
KLEx Versus FS-LASIK for the Treatment of Myopia and Compound Myopic Astigmatism
FemtoLASIK is a type of laser eye surgery used to correct vision problems such as nearsightedness, farsightedness, and astigmatism. It involves two main steps: creating a flap and reshaping the cornea.
- Conditions
- Myopia, Astigmatism, Myopic Astigmatism
- Trial name
- NCT06477081
- Testing
- FS-LASIK procedure, KLEx
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Cataract
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography
The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases.
- Trial name
- OCT IOL (NCT00532051)
- Testing
- OCT measurements
- Where
- United States
- Volunteers
- 690 people
- Sponsor
- Oregon Health and Science University
Refractive Surgery
Comparison Between the SBK Microkeratome Versus Femtosecond Laser in Flap Creation During LASIK Surgery for Myopia
LASIK is the most commonly performed refractive surgery worldwide. It has been shown to be safe and effective procedure with predictable results over long term follow ups.
- Trial name
- NCT05406973
- Testing
- SBK microkeratome versus femtosecond laser in flap creation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Myopia
A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery
Subjects will undergo SMILE surgery in one eye and LASIK surgery in their other eye to correct myopia.
- Trial name
- NCT03067077
- Testing
- SMILE, LASIK
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Astigmatism
A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and…
- Trial name
- NCT00365677
- Testing
- The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm, The Bausch & Lomb Zyoptix Tissue Saving algorithm
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors, Refractive Surgery
Femto-flap Versus SBK Flap,Predictability and Variability
Laser Insitu keratomileusis (LASIK) has become the most popular procedure for refractive error correction. Lasik flap creation is the first and critical step during LASIK surgery because of its consensual effect on a residual…
- Trial name
- NCT04684888
- Testing
- Visumax Femto-flap, Sub Bowman's keratomileusis (SBK)-flap
- Where
- Iraq
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Suzan A Rattan
Myopia, Astigmatism
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2.
- Trial name
- NCT07201298
- Testing
- Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Bilateral LASIK Surgery
A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery
This study will compare the safety and efficacy of a new eye drop formulation with REFRESH PLUS® in participants following LASIK surgery.
- Trial name
- NCT01886690
- Testing
- carboxymethylcellulose sodium based new eye drop formulation, carboxymethylcellulose sodium based eye drops
- Where
- 2 sites in Australia, Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Allergan
Chronic Ocular Pain
Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)
The study was designed to demonstrate the safety and efficacy of two dose concentrations of SAF312 eye drops (5 mg/mL and 15 mg/mL) in subjects with CICP persisting at least for 4 months after refractive or cataract surgery and…
- Trial name
- NCT04630158
- Testing
- SAF312
- Where
- 28 sites in United States, Japan and 1 more
- Volunteers
- 153 people
- Sponsor
- Novartis Pharmaceuticals
Cornea, Refractive Surgery
Evaluation of the Effect of Myopic Femtosecond Laser Assisted-LASIK on Anterior Chamber Flare Values and Corneal Endothelial Cells: A Prospective Before-and-After Study
This study aimed to investigate whether femtosecond laser-assisted LASIK (FS-LASIK) surgery causes inflammation in the anterior chamber and to analyze its effect on endothelial cells.
- Conditions
- Cornea, Refractive Surgery, Anterior Chamber Inflammation
- Trial name
- NCT04899258
- Testing
- Femtosecond laser assisted LASIK
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dry Eye
Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects Following LASIK
Collecting data using Kera Sol tear usage during the initial two-week post-operative period after Laser-Assisted In Situ Keratomileusis (LASIK) has on the signs and symptoms of surgical temporary ocular discomfort syndrome (STODS)
- Trial name
- NCT07155070
- Testing
- Kera Sol Eye Drops
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Hyperopia
Safety and Effectiveness Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Hyperopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of hyperopia, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762281
- Testing
- MEL 80 Hyperopic LASIK Treatment
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mixed Astigmatism
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of mixed astigmatism up to 6.0 D, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00761826
- Testing
- MEL 80 Mixed Astigmatism Treatment
- Where
- 5 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Ocular Infection and Inflammation
Non-Inferiority of Gatifloxacin/Prednisolone Association vs Isolated Administration in Prevention of Ocular Infection/Inflammation
The purpose of the study is to evaluate the safety and tolerance of the 0.3% gatifloxacin and 1.0% prednisolone acetate association in eye drops in the prevention of infection and inflammation after refractive surgery (Lasik) and…
- Trial name
- NCT01218737
- Testing
- 0.3% gatifloxacin and 1.0% prednisolone acetate association, isolated 0.3% gatifloxacin and 1.0% prednisolone acetate
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Myopia, Astigmatism
LASIK Surgery With a New Laser for the Treatment of Myopia Without Astigmatism
The AQUARIUZ ablation laser is a solid-state laser and has been CE approved for corneal surgery since March 2020 for the treatment of short- and longsightedness with and without astigmatism.
- Trial name
- AQUARIUZ2020 (NCT04794023)
- Testing
- Corneal Ablation
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Corneal Diseases
Using in Vivo Confocal Microscope to Evaluate the Corneal Wound Healing After Various Ocular Surgeries
Although epi-keratome laser-assisted in situ keratomileusis (Epi-LASIK), penetrating keratoplasty and pars plana vitrectomy with corneal epithelial debridement for diabetic retinopathy are surgeries commonly performed, the…
- Trial name
- NCT00491439
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital