Clinical trials: Le Fort; I
Maxilla; Hypoplasia
Transverse Maxillary Expansion With a Segmental Le Fort I Osteotomy or Surgically Assisted Rapid Maxillary Expansion (SARME)
To assess transverse dental and skeletal expansion and stability after SLFIO with no fixation of the palatal vault compared to stabilization of the palatal vault with an autogenous bone block graft or fixation of the palatal…
- Trial name
- NCT03511989
- Testing
- Bone borne distractor, Tooth borne distractor, Segmental LF1 Osteotomy group 1
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Quality of Life
Three Dimensional Evaluation of Nasolabial Changes Following Classic vs Without Alar Base Suture After Le Fort I Osteotomy
Three dimensional evaluation of nasolabial changes following classic vs without alar base suture after Le Fort I osteotomy A randomized controlled clinical trial
- Trial name
- NCT04021836
- Testing
- 3d evaluation of nasolabial change
- Volunteers
- 20 people
- Sponsor
- Cairo University
Maxillofacial Deformity, Maxillofacial Abnormalities
a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues
Following surgical operations, patients have aesthetic expectations as well as functional ones. To minimize undesirable aesthetic results after surgery and to increase the effectiveness of the surgery, the surgical method used…
- Conditions
- Maxillofacial Deformity, Maxillofacial Abnormalities, Maxillo-facial Surgery
- Trial name
- NCT07549659
- Testing
- conventional le fort I osteotomy type, subspinal le fort I osteotomy type
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Dentofacial Deformities
3D Photogrammetry Versus Commercial Scanners for Accurate Repositioning of the Maxilla for Correction of the Dentofacial Deformity.
Current advances in the three-dimensional virtual surgical planning (3D-VSP) of the orthognathic surgery have brought newer insights, enormous benefits and have become an indispensable aid for diagnosis, treatment planning and…
- Trial name
- NCT05755022
- Testing
- Maxillary Segment Repositioning
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate, Le Fort
One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I Osteotomy
Le Fort I osteotomy is often used in orthognathic surgery for patients to solve midface retrusion. It is known that post-surgical stability of Le Fort I osteotomy can be influenced by single jaw or bimaxillary procedures…
- Trial name
- NCT01871623
- Testing
- Segmental Le Fort I osteotomy, One-piece Le Fort I Osteotomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Jaw Abnormalities
A Modified Minimally Invasive Approach Towards Le Fort I Osteotomy: a Prospective Study
Nowadays, maxillary Le Fort I osteotomy is a safe and routinely performed procedure. The conventional approach is characterized by a vestibular incision extending from molar-to-molar, associated with a pterygomaxillary…
- Trial name
- MILF-I (NCT02660216)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
Discoloration, Tooth
In Vivo Assessment of Natural Tooth Color After Orthognathic Surgery. A Pilot Controlled Clinical Trial
In six consecutive patients planned to receive combined orthodontic-orthognathic surgery natural tooth color on 8 incisors was measured before initiation of the combined treatment (Time Point 1- baseline) and after its completion…
- Trial name
- NCT03657498
- Testing
- Combined orthodontic-orthognathic treatment, Standard orthodontic treatment
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Malocclusion
Finite Element Modelling of Le Fort I Osteotomy Fixation : PSI vs Miniplates
This study aimed to evaluate the biomechanical performance of patient-specific versus conventional fixation for Le Fort I osteotomy using subject-specific finite element models derived from real surgical plans.
- Trial name
- NCT07365657
- Testing
- In silico orthognathic surgery with customized implants digital only on 3D scanners
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dentofacial Deformities
Skeletal Stability of Le Fort I Osteotomy Using Patient-specific Osteosynthesis Compared to Mini-plate Fixation for Patients With Dentofacial Disharmony
The aim of the study is to evaluate the Skeletal stability of Le Fort I osteotomy using patient-specific osteosynthesis compared to Mini-plate fixation for patients with skeletal class III malocclusion.
- Trial name
- NCT05340036
- Testing
- Bimaxillary orthognathic surgery using conventional plates, Bimaxillary orthognathic surgery using patient specific plates
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hassan Fahmy Hassan Alnimr
Malocclusion, Open Bite
Effect of Customized Lateral Nasal Wall Osteotomy on the Pterygomaxillary Separation During le Fort I Down-fracture
The goal of this clinical trial is to show the effect of patient specific lateral nasal wall osteotomy to the pterygomaxillary separation during Le Fort I down-fracture. Participants will be divided into two treatment groups.
- Conditions
- Malocclusion, Open Bite, Le Fort; I, Orthognathic Surgery
- Trial name
- NCT06233188
- Testing
- orthogantic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Bezmialem Vakif University
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Surgical Procedure, Unspecified
Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized Trial
Objectives: The aims of this study are (1) to define the effectiveness of functional nasal surgery during Le Fort I osteotomy on nasal obstruction through objective as well as subjective evaluations, (2) to determine guideline…
- Trial name
- NCT01883687
- Testing
- Septoplasty
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Maxillofacial Abnormalities
Does Subspinal Le Fort I Osteotomy Affect the Nasal Airway Volume
After the description of Le Fort fractures, maxillary osteotomies are used to correct dentofacial deformities. The profile changes on nasolabial region resulting from a Le Fort I osteotomy, also that affects nasal airway.
- Trial name
- NCT06281197
- Testing
- Conventional, Subspinal
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Le Fort; I
Computer-Aided Design/Manufacturing for Le Fort I Osteotomy and 3D-customized Titanium Plate in Orthognathic Surgery
Background: In orthognathic surgery, virtual planning is gradually taking over in clinical practice. To start with, virtual surgery planning (VSP) is believed to be less time-consuming and less expensive than conventional surgery…
- Trial name
- NCT06317012
- Testing
- Le Fort I osteotomy using CAD CAM surgical guide and 3Dcustomized plate
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Hams Hamed Abdelrahman
Le Fort; I
Accuracy of LeFort I Osteotomy Fixation Using Two Plates Versus Four Plates Patient Specific Osteosynthesis
Virtual Surgical planning (VSP) has significantly improved many aspects of oral and maxillofacial surgery. A very important aspect is surgical accuracy and precise transfer of the surgical plan to the operating theatre and…
- Trial name
- NCT05908370
- Testing
- Maxillary orthognathic surgery using 4 patient specific osteosynthesis (4-Plates)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Cleft Lip Palate, Class III Skeletal Malocclusion
Evaluation of Modified Le Fort I Osteotomy for Treating Cleft Lip and Palate Patients
Nine adults with Angle class III relation and persistent alveolar bone defect due to CL/P deformity were included. SLF-1 maxillary advancement was performed.
- Conditions
- Cleft Lip Palate, Class III Skeletal Malocclusion, Le Fort; I
- Trial name
- NCT07423806
- Testing
- segmental Le Fort I (SLF-1) osteotomy
- Where
- Egypt
- Volunteers
- 9 people
- Sponsor
- Alexandria University
Orthognathic Surgical Procedures
Minimally Invasive Le Fort I Osteotomy
This is a single-center, prospective, randomized, controlled, and double-blind clinical study designed to evaluate the clinical outcomes of the minimally invasive Le Fort I osteotomy (MI-Le Fort I) compared with the conventional…
- Trial name
- NCT07279012
- Testing
- Minimally Invasive Le Fort I Osteotomy, Conventional Le Fort I Osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- TC Erciyes University
Dentofacial Deformities, Le Fort; I
Comparison Between Two Techniques to Reposition the Maxilla After le Fort 1
clinical and radiographic comparison between novel locating guide design with pre-bent titanium plates and 3d printed intermediate wafer to reposition the maxilla after Le Fort 1 osteotomy in orthognathic surgery (randomized…
- Trial name
- orthognathic (NCT06132906)
- Testing
- Orthognathic surgery (lefort1)
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital