Clinical trials: Left Atrial Rhythm
Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction
CASTLE-HFpEF (Catheter Ablation for Atrial Fibrillation Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction)
The clinical equipoise in the treatment of Atrial Fibrillation (AF) in patients with Heart Failure with mildly reduced Ejection Fraction/Heart Failure with Preserved Ejection Fraction (HFmrEF/HFpEF) reflects the scarcity of…
- Trial name
- NCT07254455
- Testing
- Catheter ablation
- Volunteers
- 900 people
- Sponsor
- Tulane University
Congestive Heart Failure, Atrial Fibrillation
Catheter Ablation for Atrial Fibrillation and Heart Failure
To compare heart function, symptoms, exercise capacity and quality of life in patients with Congestive Heart Failure (CHF) and Atrial Fibrillation (AF)before and after catheter ablation.
- Conditions
- Congestive Heart Failure, Atrial Fibrillation, Arrhythmia
- Trial name
- NCT01082601
- Testing
- Pulmonary Vein Isolation (PVI)
- Where
- 2 sites in United States
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Atrial Fibrillation, Mitral Valve Failure
Atrial Fibrillation Registry 2017
Monocentric, prospective, randomized trial of cardiac surgical arrhythmia using endocardial radiofrequency atrial ablation compared with a cryo ablation system in the setting of cardiac surgery.
- Trial name
- NCT05023590
- Testing
- ablation of left atrium during mitral valve open chest intervention
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Herz- und Gefaesszentrum Bad Bevensen
Atrial Fibrillation, Left Atrial Rhythm
Left Atrium Reservoir Function Modulation in Patients With Atrial Fibrillation: Digoxin Versus Beta Blocker
ß blocker and digoxin effect on left atrium reservoir function are unknown. This is a randomized open label study to compare the effect of theses two molecules on left atrium function
- Trial name
- NCT05540600
- Testing
- Digoxin 0.25 mg, Bisoprolol
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- University of Monastir
Persistent Atrial Fibrillation
WATCHMAN for Concomitant Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation Rhythm
WATCH-Rhythm is a prospective, randomized, multi-center, investigation to collect safety and effectiveness data on combining conventional AF ablation with LAA electric isolation and closure within a single procedure.
- Trial name
- WATCH-Rhythm (NCT03835338)
- Testing
- Pulmonary Vein Isolation, LAA Isolation, LAA Occlusion
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation (AF), Paroxysmal AF
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
The objective of this clinical investigation is to evaluate the feasibility, safety, and effectiveness of a concomitant procedure involving the Volt PFA System and Amulet 2 device in patients indicated for both AF ablation and…
- Conditions
- Atrial Fibrillation (AF), Paroxysmal AF, Persistent Atrial Fibrillation
- Trial name
- CLEAR (NCT07523620)
- Testing
- PVI Ablation, Left Atrial Appendage Occluder Implant
- Where
- 16 sites in Belgium, Czechia and 8 more
- Volunteers
- 240 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation Recurrent
SPironolactONe for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Introduction: There is evidence that aldosterone and the activation of its receptor, mineralocorticoid receptor (MR), promote cardiac fibrosis and electrical disturbances.
- Trial name
- SPONSoR (NCT06204640)
- Testing
- Spironolactone
- Volunteers
- 580 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
the Study of STABLE_SR for Persistent Atrial Fibrillation
Background:the ablation outcomes for the treatment of persistent atrial fibrillation are not as satisfactory as paroxsymal AF. The successful rate ranges from 30%-55%.
- Trial name
- STABLE-SR (NCT01761188)
- Testing
- Ablation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Atrial Fibrillation, Atrial Fibrillation, Persistent
Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm
The aim of this study is to evaluate benefits of electric cardioversion in the early and long-term postoperative period in patients after radiofrequency catheter isolation of pulmonary veins.
- Trial name
- NCT06654401
- Testing
- Transthoracic echocardiography, 24-hour ECG Monitor, Electroanatomic mapping
- Where
- Russia
- Volunteers
- 125 people
- Sponsor
- Saint Petersburg State University, Russia
Stroke, Atrial Fibrillation
Atrial Fibrillation and Premature Atrial Complexes in Patients With Ischemic Stroke.
The purpose of this study is to improve secondary prevention of ischemic stroke patients by 1. Estimating prevalence and the prognostic significance of frequent premature atrial complexes in ischemic stroke patients in relation…
- Conditions
- Stroke, Atrial Fibrillation, Premature Atrial Complexes
- Trial name
- Pacific (NCT02180542)
- Where
- Denmark
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Paroxysmal Atrial Fibrillation, Cardiac Rhythm Disorder
Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke
Cryptogenic stroke (CS) causes about 30% of admissions to a stroke unit. Silent paroxysmal atrial fibrillation (PAF) is believed to be the underlying cause of a significant proportion of patients.
- Conditions
- Paroxysmal Atrial Fibrillation, Cardiac Rhythm Disorder, Left Atrial Dilatation, Cryptogenic Stroke
- Trial name
- CRIPTO-FAST (NCT06542770)
- Testing
- Early implant of cardiac monitor
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc de Salut Mar
Cryptogenic Stroke, Atrial Fibrillation
Atrial Imaging and Cardiac Rhythm In Embolic Stroke
The ARIES study is an observational study in which patients with a recent acute ischemic stroke of cryptogenic aetiology are consecutively enrolled in order to perform a extensive cardiologic work-up.
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Atrial Dilatation, Stroke, Ischemic
- Trial name
- ARIES (NCT05486221)
- Testing
- Extensive cardiologic work-up
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Ischemic Stroke, Left Atrial Strain
Left Atrial Strain Assessment in Ischemic Stroke Patients
This study is investigating a potential link between a novel measurement made on cardiac ultrasound and the risk of ischemic stroke in patients with a normal heart rhythm. The novel measurement is called left atrial strain.
- Conditions
- Ischemic Stroke, Left Atrial Strain, Sinus Rhythm
- Trial name
- ASSISTANT (NCT07102693)
- Where
- Ireland
- Volunteers
- 468 people
- Sponsor
- Connolly Hospital Blanchardstown
Arrhythmias, Cardiac, Atrioventricular Block
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical…
- Conditions
- Arrhythmias, Cardiac, Atrioventricular Block, Reduced Systolic Function, Atrial Fibrillation
- Trial name
- TREEBEARD (NCT06324682)
- Testing
- Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)
- Where
- 31 sites in Italy
- Volunteers
- 8,400 people
- Sponsor
- University Hospital of Ferrara
Atrial Fibrillation
CPVI Alone Versus. CPVI Plus Electrophysiological Substrate Ablation in the LA During SR for the Treatment of Non-PAF
The primary objective of this investigation is to compare the efficacy of two different AF ablation strategies in patients with non-paroxysmal AF: CPVI plus electrophysiologic substrate ablation in the left atrium during sinus…
- Trial name
- STABLE-SR_II (NCT03448562)
- Testing
- CPVI, STABLE-SR
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Atrial Fibrillation
Measurement of Left and Right Atria From CT Scans of Cardiac Rhythm Disorder Cases
The purpose of this study is to gather information about the size and shape of patients' hearts in order to design a device.
- Trial name
- NCT01165593
- Testing
- There is no intervention that is a part of this study.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- Kardium Inc.