Clinical trials: Leg Injuries
Iliotibial Band Syndrome
Shearwave Elastography in the Evaluation of Iliotibial Band Syndrome
Iliotibial band syndrome (ITBS) is a condition frequently treated in physiotherapy. The pathophysiology underlying this syndrome is still poorly understood.
- Trial name
- NCT05427110
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Groin Injury
Comparison of the Effect of Copenhagen Adduction Exercises Performed at Different Load-intensity
The aim of our study is to compare the effects of the Copenhagen adduction exercise, performed at different loading intensities, on hip muscle strength development, performance, flexibility, and delayed onset muscle soreness.
- Trial name
- NCT06104722
- Testing
- High-intensity Copenhagen adduction exercise, Low-intensity Copenhagen adduction exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Impact of Fascia Iliaca Block in Hip Fracture Patients
The study is a prospective randomized examining the impact of fascia iliaca block on perioperative pain control and post operative ambulation in patients with hip fractures.
- Trial name
- NCT03525977
- Testing
- Fascia iliaca block arm
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Diabetes, Wound Infection
Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of a broad-spectrum orally bioavailable carbapenem, tebipenem pivoxil hydrobromide (SPR994) (Spero Therapeutics, Inc.), into the extracellular, interstitial fluid of soft tissue in…
- Conditions
- Diabetes, Wound Infection, ABSSSI, Healthy Volunteers
- Trial name
- NCT04919954
- Testing
- Tebipenem Pivoxil Hydrobromide
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Anterior Cruciate Ligament Injuries
Muscle Architecture and Anterior Cruciate Ligament
The aim of this study is to examine the effects of plyometric training on biceps femoris longus (BFl) and vastus lateralis (VL) muscle architecture in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04690127
- Testing
- Plyometric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ankle Fracture
Is Deltoid Ligament Repair for Ankle Fracture Necessary?
The investigator hypothesizes that primary acute ankle deltoid ligament repair can help restore ankle radiographic congruity and functional outcomes.
- Trial name
- AnkleFX (NCT02863042)
- Testing
- Repair Deltoid Tendon, Ankle Fracture Without Deltoid Tendon Repair
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Spinal Cord Injury
Can Vibration Stimulation of the Foot Sole Activate Leg Muscles?
Participants will be asked to complete three different tests (standing, stepping and assisted walking) and will experience three different experimental conditions during each test.
- Trial name
- NCT02043106
- Testing
- plantar vibration
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Hip Fractures
Fragility Fracture Integrated Rehabilitation Management (FIRM)
A number of studies for clinical pathway (CP) after hip fracture have been suggested to improve post-fracture outcome. However, CP is not carried out properly in most countries due to inadequate system and awareness, and lack of…
- Trial name
- FIRM (NCT03430193)
- Testing
- FIRM, Conventional rehabilitation
- Where
- South Korea
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Patellofemoral Pain Syndrome, Exertional Lower Leg Pain
Prevention of Injuries by an Exercise Program - a RCT
Overuse injuries are a major concern for physical active individuals. Study hypothesis is that an exercise programme based on known intrinsic risk factors can prevent overuse injuries in soldiers undergoing basic military…
- Trial name
- NCT00348647
- Testing
- physical training program to prevent injuries
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Lower Extremity Problem
Injury Prevention for Female Lacrosse Athletes
In this pilot study the investigators are testing whether an injury prevention program will help improve quality of movement and decrease number of injuries in collegiate women's lacrosse athletes.
- Trial name
- NCT06255899
- Testing
- Education Program on Injury Prevention, Individualized Feedback + Education Program on Injury Prevention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Investigation of the Effects of Proprioceptive Exercises After Anterior Cruciate Ligament Surgery
The aim of this study is to investigate the effects of proprioceptive exercises on balance, kinesiophobia, and functionality after anterior cruciate ligament surgery.
- Trial name
- NCT07333092
- Testing
- control, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Ankle Sprains
Ankle Injuries, Imaging and Prevention Program Effectiveness in New Army Recruits
Infantry recruits will undergo a musculoskeletal examination to assess tendon, muscle, proprioception, agility, and joint status.
- Trial name
- NCT06469099
- Testing
- excercises
- Where
- Israel
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Chronic Ankle Instability, Ankle Sprains
A Study Investigating The Effects Of An Ankle Rehabilitation Program On High School Athletes With Ankle Instability
A randomized controlled trial investigating the effects of a 4-week ankle rehabilitation program on high school athletes with chronic ankle instability.
- Conditions
- Chronic Ankle Instability, Ankle Sprains, Ankle Rehabilitation
- Trial name
- NCT03447652
- Testing
- Resistance Band Ankle Rehabilitation, Biomechanical Ankle Platform System Rehabilitation, Combination Rehabilitation
- Where
- 7 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Wound Healing
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single and Repeated Doses of Topical GSK1278863
This is a randomized, placebo-controlled, single-blind (subjects and investigators will be blinded, GSK internal personnel will not be blinded), parallel-group, two part (Part A, Part B) trial in healthy volunteers and subjects…
- Trial name
- NCT01831804
- Testing
- GSK1278863
- Where
- 7 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bone Fracture
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Trial name
- NCT05751304
- Testing
- Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anterior Cruciate Ligament Injuries
Neuromuscular Rehab for ACL Reconstruction: Knee Function & Brain Plasticity
This study focuses on patients with anterior cruciate ligament (ACL) rupture and reconstruction, aiming to systematically investigate the clinical efficacy and underlying mechanisms of neuromuscular training in restoring knee…
- Trial name
- NCT07243860
- Testing
- Neuromuscular Training, Conventional Rehabilitation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Hip Fractures, Anesthesia Local
Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Postoperative
- Trial name
- NCT02255591
- Testing
- Lidocaine-adrenaline added gadolinium.
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
ACL - Anterior Cruciate Ligament Rupture
Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells
Collagen based -membrane derived from amniotic tissue can be used to help reestablish the natural synovial lining of the reconstructed ACL, in effect acting as both a barrier from the synovial fluid and as a scaffold to contain…
- Trial name
- BioACLRCT (NCT03294759)
- Testing
- Bio ACL, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation