Clinical trials: Leg Injuries and Disorders
Hypotension, Pleth Variability Index
Pleth Variability Index and Hypotension
Correct assessment of a patient's volume status is the most important goal for an anesthetist. However, most of the variables used for fluid response evaluation are invasive and technically challenging.Pulse oximeter is a…
- Trial name
- NCT02984956
- Testing
- pleth variability index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzincan University
Diabetic Foot, Diabetes Mellitus
Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS)
The planned study is a Randomized Controlled Monocentric Trial, which will provide evidence on whether early angiography in percutaneous transluminal angioplasty (PTA) readiness ("immediate" treatment, within 48h) has advantages…
- Conditions
- Diabetic Foot, Diabetes Mellitus, Peripheral Arterial Disease, Diabetic Neuropathies
- Trial name
- PTA-DFS (NCT06124586)
- Testing
- Percutaneous transluminal angioplasty
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Sarcopenia, Hip Fracture
Prevalence and Pathophysiology of Sarcopenia in the Elderly Patient With Hip Fracture
Sarcopenia is the loss of muscle mass and function that accompanies aging. The term sarcopenia comes from the Greek "sarx" (flesh) and "penia" (loss).
- Conditions
- Sarcopenia, Hip Fracture, Frailty
- Trial name
- PREFISSARC (NCT01477086)
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Diabetic Foot Ulcer
Treating Diabetic Foot Ulcers, Comparing Two Topical Antimicrobial Agents, Dakin´s and Prontosan
202 Diabetic foot ulcers will be cleaned with either Hypochlorous Acid, HClO or Polyhexamethylene biguanide, PHMB twice a week until healed or 24 weeks.
- Trial name
- NCT05132179
- Testing
- Dakins Full Strength Solution, 0.5% Topical Solution, HOCl solution
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Vastra Gotaland Region
Tendinopathy
Effect of Eswt on Muscle Architecture
The aim of the research is to investigate the effect of Ekstracorpereal shock wave treatment (ESWT) on muscle strength, flexibility and architecture of the lower extremity tendinopathies when applied using the frequencies…
- Trial name
- NCT04410705
- Testing
- Extracorporeal shockwave theraphy for hamstring tendinopathy, Extracorporeal shockwave theraphy for quadriceps tendinopathy, Extracorporeal shockwave theraphy for achilles tendinopathy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Stroke, Hip Fractures
Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward
The aim of this study is to investigate the effectiveness of our developed week-treatment program GAPP, on strength, balance, speed, functionality and cognition, with the main goal to achieve a better independence for activities…
- Conditions
- Stroke, Hip Fractures, Abdominal Injury, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT03109483
- Testing
- Geriatric Activation Program Pellenberg
- Where
- Belgium
- Volunteers
- 111 people
- Sponsor
- KU Leuven
Intertrochanteric Fractures, Hip Fractures
Liposomal Bupivacaine Fascia Iliaca Block for Perioperative Sleep Quality in Elderly Patients With Intertrochanteric Fracture
Older adults with hip fracture often experience severe pain before and after surgery. This pain can cause anxiety and poor sleep, and may increase the risk of postoperative delirium (sudden confusion after surgery).
- Conditions
- Intertrochanteric Fractures, Hip Fractures, Sleep Disturbance, Postoperative Delirium
- Trial name
- NCT07892859
- Testing
- Liposomal Bupivicaine, Saline Solution (NaCl 0,9%)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Li Xiaoyuan
Kinesiophobia, Anterior Cruciate Ligament Injuries
Stress Response to Virtual Risky Movement Exposure and Kinesiophobia After Anterior Cruciate Ligament (ACL) Surgery
In this study, patients who have completed their rehabilitation after Anterior Cruciate Ligament (ACL) reconstruction surgery will be examined with physiological stress response test while being exposed to risky athletic…
- Trial name
- NCT05929261
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ege University
Femur Fracture
Utility of Pulmonary Echography for Evaluation of Patients Undergoing Orthopedic Surgery for Femur Fracture
The stratification of perioperative risk is an essential moment in the preoperative evaluation of the patient undergoing surgery especially in the setting of urgency.
- Trial name
- LUSHIP (NCT04074876)
- Testing
- Pulmonary echography
- Where
- Italy
- Volunteers
- 877 people
- Sponsor
- University of Udine
Cartilage Injury, Knee Injuries
7T MRI to Evaluate Cartilage Defects in the Knee
The investigators propose to prospectively evaluate the accuracy of a novel 7-Tesla (7T) knee MRI protocol for the detection and grading of cartilage lesions in the knee, which is a significant limitation of current MRI…
- Conditions
- Cartilage Injury, Knee Injuries, Arthropathy of Knee, Cartilage Damage
- Trial name
- NCT04118023
- Testing
- 7 Tesla Magnetic Resonance Imaging Test
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- The Methodist Hospital Research Institute
Hip Fractures, Neuromuscular Blockade
Continuous Fascia Iliaca Block for Acute Hip Fractures
Hip fractures are a major cause of morbidity and mortality in the elderly with over 30,000 hip fractures occuring in Canada annually and over 1300 in Saskatchewan.
- Conditions
- Hip Fractures, Neuromuscular Blockade, Respiratory Morbidity, Delirium
- Trial name
- NCT03588689
- Testing
- Continuous fascia iliaca block, Ropivacaine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Saskatchewan
Chronic Wound, Burn Wound
Wound Healing Endpoint and Recurrence
This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment…
- Conditions
- Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers
- Trial name
- NCT02577120
- Testing
- Epiceram Skin Barrier Function, Vaseline Petroleum Jelly
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sashwati Roy
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Knee Osteoarthritis, Knee Injuries
Para-sartorial Compartment Block in Knee Surgery
Selective blockade of the saphenous nerve branches is among the regional anesthesia techniques in knee surgery. In this block, analgesia is provided without motor block and is an essential advantage in terms of early mobilization…
- Conditions
- Knee Osteoarthritis, Knee Injuries, Knee Disease, Knee Arthritis
- Trial name
- NCT05566561
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Gonarthrosis; Primary, Degenerative Joint Disease of Knee
The Effect of Three Prosthesis Designs in Total Knee Arthroplasty
The purpose of this study is to compare three prosthesis designs to compare three prosthesis designs for total knee arthroplasty and determine the best option for patients in need of a knee replacement.
- Trial name
- NCT03059927
- Testing
- Knee arthroplasty, Cruciate retaining, Knee arthroplasty, Anterior stabilized, Knee arthroplasty, Posterior stabilized
- Where
- 2 sites in Norway
- Volunteers
- 216 people
- Sponsor
- Lovisenberg Diakonale Hospital
Lower Extremity Injuries, Venous Thromboembolism (VTE)
TRiP-cast Score Validation and Evaluation of Adherence to Preventive Anticoagulant Treatment in Patients With Lower Limb Trauma Requiring Immobilization
This is a prospective, multicenter, observational cohort study designed to externally validate the Trauma-Related Immobilization-related Prophylaxis (TRiP(cast)) score in Tunisian adults with acute lower-limb trauma requiring…
- Conditions
- Lower Extremity Injuries, Venous Thromboembolism (VTE), Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- TRiP-VALID (NCT07863115)
- Testing
- Low-Molecular-Weight Heparin (LMWH), Direct Oral Anticoagulants (DOACs), No Thromboprophylaxis Cohort
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Medial Tibial Stress Syndrome
Medial Tibial Stress Syndrome Prevention
This randomized controlled trial investigated whether a 10-week heavy resistance training program reduced the incidence of medial tibial stress syndrome (MTSS) in collegiate indoor track and field athletes.
- Trial name
- NCT07256808
- Testing
- Resistance Training
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rowan University
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Diabetic Foot Ulcer, Diabetes Mellitus (DM)
Evaluating the Efficacy of Pulsating Electromagnetic Field Therapy by CRAD ULCER X-01 for Diabetic Foot Ulcers
Background: Diabetic foot ulcer (DFU) is a frequent complication of chronic, uncontrolled diabetes mellitus (DM). Treatment with antibiotics, daily dressing, wound debridement, and wound off-loading is often prescribed.
- Trial name
- NCT07465640
- Testing
- Pulsating electromagnetic field
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- National Defence University of Malaysia
Leg Ulcers, Leg Ulcers Venous
Vacuum Compression Therapy and Tissue Oxygenation in Chronic Leg Ulcers
Chronic lower limb ulcers, particularly those of venous etiology, are difficult-to-heal wounds that severely affect patients' quality of life. Adequate tissue oxygenation is essential for wound healing.
- Trial name
- NCT07901517
- Testing
- Vacuum Compression Therapy (VCT), Standard Wound Care
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- BTL Industries Ltd.
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