Clinical trials: Lens Disease
Dry Eye Syndromes
Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control
This study will evaluate the increase in comfort and comfortable contact lens (CL) wear time associated with application of TrueTear (active intranasal neurostimulation) compared with application of TrueTear sham control…
- Trial name
- NCT03325673
- Testing
- TrueTear
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Allergan
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Lens Subluxation
Sutureless Technique for Repositioning and Scleral Fixation of the Capsular Bag - Intraocular Lens Complex With Permanent Use of Iris Retractors
Sutureless technique for repositioning and scleral fixation of the capsular bag-intraocular lens complex with permanent use of iris retractors
- Trial name
- NCT07257172
- Testing
- Sutureless technique for repositioning and scleral fixation of the capsular bag - intraocular lens complex with permanent use of iris retractors
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Military Institute od Medicine National Research Institute
Dry Eyes
Virgin Coconut Oil Contact Lens as Ocular Rewetting Agent
This is a clinical trial where 44 subjects dry eyes were instilled with Virgin Coconut Oil (VCO CL) using contact lenses as its vehicle.
- Trial name
- VCOCL (NCT06071780)
- Testing
- organic product - Virgin Coconut Oil
- Where
- Malaysia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Cataract
Tolerability and Toxicity of Topically Applied Nepafenac 0.3% vs Ketorolac 0.5%
This study will examine the tolerability and toxicity of topically applied Nepafenac 0.3% vs ketorolac 0.5% among patients undergoing cataract surgery.
- Trial name
- NCT02752646
- Testing
- nepafenac 0.3%, ketorolac
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- MDbackline, LLC
Cataract
OCT-PRO Model vs. Clinicians: Cataract Surgery Outcome Prediction
Cataract is the leading cause of blindness worldwide, yet 5-20% of patients fail to achieve satisfactory visual recovery after surgery.
- Trial name
- NCT07713069
- Testing
- OCT-PRO prediction model, Routine Preoperative Counseling
- Volunteers
- 534 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Surgery, Cataract
Routine Surgical Procedures During COVID-19 Pandemic: a French Nationwide Cohort Study
Determine the consequences of COVID-19 pandemic on routine targeted surgeries. Five surgical procedures were considered : cataract surgery, hip and knee arthoplasties, coronary revascularisation by angioplasty and definitive…
- Conditions
- Surgery, Cataract, Hip Arthroplasty, Knee Arthroplasty
- Trial name
- NCT05197660
- Testing
- surgical procedures
- Where
- France
- Volunteers
- 2,000,000 people
- Sponsor
- EPI-PHARE
Cataract
Evaluation of Performance of New IFIS Sleeve
A silicone sleeve will be used on the hydrodissection needle to avoid that the iris can prolaps through the gap between needle and incision wound.
- Trial name
- NCT06067360
- Testing
- IFIS sleeve
- Volunteers
- 20 people
- Sponsor
- Medicel AG
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
The purpose of this study is to determine whether the prescription determined for a new daily disposable toric contact lens will be a good match to a prescription determined for an existing brand of lens.
- Trial name
- NCT01120782
- Testing
- etafilcon A toric contact lens with new wetting agent, etafilcon A toric contact lens
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types
To evaluate and compare the performance of two monthly replacement multifocal contact lenses in existing wearers.
- Trial name
- NCT06232590
- Testing
- Control Lens (comfilcon A), Test Lens (lehfilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Errors
Clinical Performance of Two Daily Disposable Contact Lenses - Study 1
The purpose of this study is to evaluate end of day (EOD) visual acuity (VA) at distance when wearing Precision1™ contact lenses compared to Acuvue® Moist contact lenses.
- Trial name
- NCT03969290
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- Alcon Research
Posterior Capsule Opacification
Influence of CleaRing Open-capsule Device on Refractive Predictability in Cataract Patients (Part 2)
The Hanita CleaRing device is an intraocular implant designed for inhibition of PCO leading to reduction in the Nd:YAG treatment rate.
- Trial name
- CleaRing (NCT06083025)
- Testing
- CleaRing
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Myopia, Refractive Errors
Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial
This is a single-center, randomized, double-blind, controlled study to test whether a new type of eyeglass lens - a "dual-action" lens that combines two technologies (multiple defocus zones and dot diffusion) - can slow the…
- Trial name
- NCT07854457
- Testing
- Dual-Action Myopia-Control Spectacle Lens, Stellest Myopia-Control Spectacle Lens（Highly Aspherical Lenslet Target / HALT Lens）
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Dry Eye
Tear Evaluation Between Habitual Contact Lens Wearers and Non Contact Lens Wearers
to evaluate tears between habitual contact lens wearers and non contact lens wearers
- Trial name
- NCT01317030
- Testing
- Contact Lens Wear, Non-Contact Lens Wear
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Evaluating the Efficacy and Safety of Contact Lens Lubricant in Rigid Gas Permeable Corneal Contact Lens Wearers
This trial aims to evaluate the safety and effectiveness of LACRIFRESH OCU-DRY 0.3% OSD, a contact lens lubricant produced by AVIZOR, S.A.
- Trial name
- NCT07091825
- Testing
- LACRIFRESH OCU-DRY 0.3% OSD, Rigid contact lens lubricant
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Avizor SA
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Sjögren's Syndrome Patients With Severe Dry Eye
Evaluation of Therapeutic Effect of Bandage Contact Lenses ( BCL) on Dry Eye Caused by Sjogren's Syndrome
The purpose of this study is to evaluate the therapeutic effect and safety of therapeutic bandage contact lenses treating dry eye caused by Sjögren's syndrome.
- Trial name
- BCL (NCT02147509)
- Testing
- 0.02% Fm, SH, 0.02% Fm, SH, 0.05% CsA, 0.02% Fm, SH, tBCL
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Jinyang Li
Presbyopia
Clinical Performance of a Phakic Intraocular Lens (IOL)
This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add.
- Trial name
- NCT03499821
- Testing
- EDOF ICL
- Where
- 6 sites in Belgium, Spain
- Volunteers
- 41 people
- Sponsor
- Staar Surgical Company
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