Clinical trials: Lens Implantation, Intraocular
Cataract
Clinical Investigation of the Next-Generation Intraocular Lens
This study is a 6-month, prospective, multicenter, bilateral, randomized clinical investigation of the TECNIS Model ZHR00 and Model ZQR00 IOLs versus the TECNIS Symfony control IOL.
- Trial name
- NCT03111550
- Testing
- Investigational Intraocular Lens Device #1: TECNIS Model ZHR00, Investigational Intraocular Lens Device #2: TECNIS Model ZQR00, TECNIS Symfony® Extended Range of Vision Intraocular Lens: Model ZXR00
- Where
- 12 sites in United States
- Volunteers
- 242 people
- Sponsor
- Abbott Medical Optics
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Cataract Senile
Evaluation of an Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04793789
- Testing
- monofocal toric lens
- Where
- France
- Volunteers
- 249 people
- Sponsor
- Carl Zeiss Meditec AG
Multifocal Intraocular Lenses, Extended Depth of Focus
Low Add Multifocal Versus Extended Depth of Focus Intraocular Lens
The innovations in phacoemulsification surgery and advances in surgical equipment ensure a safe extraction of the crystalline lens and implantation of intraocular lenses (IOL).
- Trial name
- NCT04865016
- Testing
- Tecnis +2.75 D (ZKB00) and Tecnis Symfony (ZXR00)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Marmara University
Cataract, Juvenile
Optic Capture Without Anterior Vitrectomy in Pediatric Cataract Surgery
Purpose: To compare two pediatric cataract surgery procedures: intraocular lens (IOL) optic capture without anterior vitrectomy (AV) and in-the-bag IOL implantation with AV.
- Trial name
- NCT05461040
- Testing
- optic capture, In-the-bag implantation of Intraocular lens
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Ege University
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataracts
A Real-World Study for the TECNIS Synergy™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Synergy™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090826
- Testing
- Model ZFR00V
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Vision Performance Evaluation of TECNIS EYHANCE™ With TECNIS SIMPLICITY™ Compared to TECNIS® 1-piece Intraocular Lenses
This study is a 6-month, prospective, multicenter, bilateral, randomized subject- and evaluator-masked, clinical investigation of the TECNIS Eyhance IOL versus the TECNIS 1-piece IOL.
- Trial name
- NCT05025345
- Testing
- Tecnis Eyhance, Tecnis 1 piece IOL
- Where
- 15 sites in United States
- Volunteers
- 228 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Clinical Investigation of a New Intraocular Lens
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Symfony Extended Range of Vision IOL.
- Trial name
- NCT02203721
- Testing
- TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Optics
Intraocular Lens
Comparison of the Visual Performance After Implantation of Multifocal Lens
This is a prospective, consecutive, nonrandomized,comparative study. Comparison of the Visual Performance After Implantation of a Trifocal Intraocular Lens and Two Bifocal Intraocular Lenses
- Trial name
- NCT03586271
- Testing
- trifocal lens, bifocal lens 1, bifocal lens 2
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Cataract
Clinical Investigation of the Next-Generation Intraocular Lenses
This study is a 6-month, prospective, multicenter, subject/evaluator-masked, bilateral, randomized clinical investigation of the TECNIS Next-Generation Model ZFR00 and Model ZYR00 IOLs versus the TECNIS Multifocal Model ZLB00…
- Trial name
- NCT03372434
- Testing
- Investigational Intraocular Lens Device #1: Model ZFR00, Investigational Intraocular Lens Device #1: Model ZYR00, TECNIS Multifocal Intraocular Lens: Model ZLB00
- Where
- 12 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Astigmatism
Use of Toric Intraocular Lens to Neutralize Keratometric Astigmatism
The purpose of this study is to evaluate neutralization of keratometric astigmatism in patients with cataract and astigmatism higher than 1 diopter, with phaco surgery and the implantation of a toric intraocular lens.
- Trial name
- NCT00925886
- Testing
- Acrysof Toric one-piece intraocular lens
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Cataract, Binaural Beats
Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients
The purpose of this study is to evaluate the effects of binaural beats on patient satisfaction and intraoperative comfort in patients aged 65 years or older undergoing cataract surgery (phacoemulsification and posterior chamber…
- Conditions
- Cataract, Binaural Beats, Geriatric Anesthesia
- Trial name
- NCT07609186
- Testing
- binaural beats
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Cataract, Near Vision
The Best Way to Improve the Near Visual Acuity After ZXR00 IOL Implantation
The Best Way to Improve the Near Visual Acuity After ZXR00 IOL Implantation
- Trial name
- NCT05594537
- Volunteers
- 30 people
- Sponsor
- Yune Zhao
Cataract
Influence of an Capsular Tension Ring on the Rotation of an Intraocular Lens (Aspira®-aA Also Known as MC 6125 AS)
The purpose of this study is to observe the axial IOL rotation after surgery with a capsular tension ring (CTR) and a MC6125 AS IOL.
- Trial name
- NCT02649257
- Testing
- cataract surgery, intraocular lens (MC 6125 AS), capsular tension ring (CTR 13/11)
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cataract
DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses
The investigators seek to assess the effect of pre-operative and continued post-operative corticosteroid use on pain, patient preference, visual outcomes, and change in objective quantifiable biological parameters in patients…
- Trial name
- NCT04479748
- Testing
- Dexamethasone, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Prism Vision Group
Aphakia, Cataract
Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT03895034
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- RxSight, Inc.
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract
A Dynamic Study of Pupil Diameter After Artificial Lens Implantation in Patients With High Myopia
Age-related cataract remains the leading cause of blindness in developing countries. And, with the aging of the population in these countries, the number of cataract patients will continue to grow.
- Trial name
- NCT06505434
- Testing
- Cataract surgery
- Volunteers
- 60 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Assessment
Visual Performance After RESTOR Implantation
The purpose of this study is to evaluate the distance, intermediate, and near vision after aspheric multifocal diffractive AcrySof® ReSTOR SN6AD1 intraocular lens (IOL) implantation.
- Trial name
- NCT01065064
- Testing
- RESTOR IOL
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia