Clinical trials: Lentigines
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06268496
- Testing
- serum formula 2039125 03
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Solar Lentigines
Laser Removal of Age (Sun) Spots on Hands
The purpose of this study is to determine whether picosecond laser is effective in the treatment of age (sun) spots.
- Trial name
- NCT01885871
- Testing
- Picosecond QS Nd:YAG Laser
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cutera Inc.
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06234527
- Testing
- tested product
- Where
- Senegal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Lentigines
A Single-Center 2-Arm Study for Lentigines on the Hands
The purpose of this study is to evaluate the effectiveness and safety of two laser systems for improvement of lentigines on the hands.
- Trial name
- NCT02763072
- Testing
- Enlighten Laser, Excel V Laser
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Solar Lentigo, Senile Lentigo
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.
CS5_3 aims to evaluate the tolerance and to adjust the mode of administration of 4 different conditions of cryotherapy treatments applied on the brown spots of the face and hands with 3 prototypes.
- Conditions
- Solar Lentigo, Senile Lentigo, Post-inflammatory Hyperpigmentation
- Trial name
- NCT05625815
- Testing
- Prototypes (816-v1 001) to (816-v1 050), Prototype (816-v1 051) to (816-v1 100), Prototypes (816-v1 101) to (816-v1 150)
- Where
- South Africa
- Volunteers
- 32 people
- Sponsor
- Cryonove Pharma
Lentigo, Hyperpigmentation
Efficacy and Tolerance of D-pigment Versus Moisturizer in Hands' Lentigo Lesions With or Without Laser Therapy
Pierre Fabre Dermo-Cosmétique has commercialized a cosmetic product (D-pigment rich texture) for treatment of hyperpigmentation.
- Trial name
- NCT03457246
- Testing
- D-Pigment rich texture, Hydrance optimale riche
- Volunteers
- 40 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Actinic Keratosis, Actinic Lentigo
MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis
The aim of this study is to evaluate effectiveness of a serum containing 0.3% of MRB, a cosmetic active ingredient, against actinic lentigo and actinic keratosis.
- Trial name
- NCT05152407
- Volunteers
- 35 people
- Sponsor
- NAOS Institute of Life Science
Solar Lentigo
Tolerance and Mode of Administration of Cyto-selective Cryotherapy Treatments in Face Brown Spots: Proof of Concept
Solar lentigos or lentigines are harmless patch of darkened skin, of different sizes and colors, due to the exposure to UV radiation. They are very common, especially in people over the age of 40 years old.
- Trial name
- AGILE2 (NCT05203263)
- Testing
- (810A-v1) device prototype, (810B-v1) device prototype, (810C-v1) device prototype
- Where
- Ukraine
- Volunteers
- 23 people
- Sponsor
- Cryonove Pharma
Post-inflammatory Hyperpigmentation, Melasma
A Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult Participants
The study aims to evaluate the efficacy of a facial sunscreen under two experimental conditions-untinted and tinted-in improving facial spots (melasma and solar lentigines/post-inflammatory hyperpigmentation) after 8 weeks of…
- Conditions
- Post-inflammatory Hyperpigmentation, Melasma, Solar Lentigo
- Trial name
- El Porto Ex-US (NCT07679945)
- Testing
- Sunscreen untinted, Sunscreen tinted
- Where
- Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Lentigo, Solar Lentigo
Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face
The goal of this clinical trial is to compare the 3 different prototype of cyto-selective cryotherapy devices (name of the devices : CRYONOVE) use in brown spots on the face of subject from different ethnicities.
- Conditions
- Lentigo, Solar Lentigo, Post Inflammatory Hyperpigmentation
- Trial name
- CS5_10B (NCT06305897)
- Testing
- CRYONOVE (EC14_4osc), CRYONOVE (EC+05_1osc), CRYONOVE (EC+05_2osc)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cryonove Pharma
Solar Lentigo
CLINICAL INVESTIGATION TO EVALUATE THE EFFICACY AND SAFETY OF EPILADY PROTOTYPE DEVICE FOLLOWED BY APPLICATION OF A TOPICAL FORMULA ON DEPIGMENTATION OF LENTIGO SPOTS
To assess the efficacy of the Epilady investigational device, used with and without a topical depigmenting formula, in reducing the appearance of lentigo spots on the hands and forearms of healthy female participants over an…
- Trial name
- EPILADY (NCT07239726)
- Testing
- LASER, LASER AND ACTIVE FORMULA
- Where
- Mauritius
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Melasma, Lentigines
A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin
The purpose of this investigation is to evaluate safety and efficacy of the Cutera enlighten dual-pulse duration, dual-wavelength 532nm KTP/1064nm Nd:YAG laser for the treatment of melasma and lentigines on the face in Asian skin.
- Trial name
- NCT02385994
- Testing
- enLighten Laser
- Where
- 2 sites in China, Japan
- Volunteers
- 80 people
- Sponsor
- Cutera Inc.
Hyperpigmentation
Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06253468
- Testing
- tested product
- Where
- Singapore
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Facial Solar Lentigines
Study for the RevLite Laser System for Facial Solar Lentigines
The purpose of this study is to evaluate the effects of the Revlite Laser System for treatment of facial solar lentigines
- Trial name
- NCT02110108
- Testing
- Revlite Laser System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Solar Lentigo, Senile Lentigo
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation)
CS5_7 study aim to evaluate the tolerance and to adjust the mode of administration of two conditions of cryotherapy treatment applied on the brown spots of the face and hands with 1 prototype (816-v1).
- Conditions
- Solar Lentigo, Senile Lentigo, Post Inflammatory Hyperpigmentation
- Trial name
- NCT05883657
- Testing
- Condition 1 : Prototypes (816-v1) every weeks, Condition 2 : Prototypes (816-v1) every two weeks
- Where
- South Africa
- Volunteers
- 80 people
- Sponsor
- Cryonove Pharma
Solar Lentigo
Tolerance of Cyto-selective Difluoroethane-based Cryotherapy
Cryotherapy is more and more used to improve skin appearance. Devices using difluoroethane, manufactured by CRYONOVE PHARMA, are already available on the local and international markets, e.g.
- Trial name
- AGILE3 (NCT05322668)
- Testing
- Prototypes (812A-v1), (812C-v1), (812D-v1) and (812F-v1)
- Where
- Ukraine
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cryonove Pharma
Hyperpigmentation
Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and Lentigos
This is a randomized, observer-blinded, vehicle-controlled multi-dose trial that examines the effect of twice daily application of 0.8% DBI-102 Gel, 4% Hydroquinone cream, and Vehicle Gel for 12 weeks in adults with Fitzpatrick…
- Trial name
- NCT05511948
- Testing
- DBI-102, Vehicle gel, Hydroquinone Cream
- Where
- El Salvador
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- DermBiont, Inc.
Skin Cancer, Cutaneous Tumor
Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for Malignant Cutaneous Tumors
- Conditions
- Skin Cancer, Cutaneous Tumor, Cutaneous Metastasis
- Trial name
- NCT04068155
- Testing
- DaRT- Diffusing Alpha-emitters Radiation Therapy
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Alpha Tau Medical LTD.
Lentigo Solar, Senile Lentigo
Tolerance and Performance (Mode of Administration) of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots
CS5_8 study aim to evaluate the tolerance and to adjust the mode of administration of 2 different conditions of cryotherapy treatments applied on the brown spots of the face with 1 prototype (816-v1).
- Trial name
- NCT05793619
- Testing
- Prototypes (816-v1 301) to (816-v1 355) every week, Prototypes (816-v1 301) to (816-v1 355) every two weeks
- Where
- Georgia
- Volunteers
- 20 people
- Sponsor
- Cryonove Pharma
Solar Lentigo
Evaluation of Broadband Light Treatment for Solar Lentigines
Broadband light treatment for Solar Lentigines
- Trial name
- NCT06363240
- Testing
- Broadband Light
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Sciton