Clinical trials: Lesion
Alzheimer Disease
A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects.
Study of the Safety, tolerability and pharmacokinetics with multiple doses of donepezil patch in healthy male subjects
- Trial name
- NCT02178124
- Testing
- Donepezil
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Icure Pharmaceutical Inc.
Coronary Arterial Disease (CAD), de Novo Lesions in Native Coronary Arteries
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
AGENT DCB STANCE is a prospective, multicenter, open-label, 1:1 randomized controlled study designed to assess the safety and effectiveness of a treatment strategy with the AGENT Drug-Coated Balloon compared to standard of care…
- Trial name
- NCT06959524
- Testing
- Drug Eluting Balloon, Drug eluting stent, Plain old balloon angioplasty
- Where
- 71 sites in United States, Australia and 7 more
- Volunteers
- 1,616 people
- Sponsor
- Boston Scientific Corporation
Kidney Neoplasms
Tracking Renal Tumors After Cryoablation Evaluation
TRACE is an observational, open-label, single-arm, multi-center registry of subjects who have undergone renal lesion cryoablation per their physician's standard of care.
- Trial name
- TRACE (NCT01117779)
- Testing
- Cryoablation
- Where
- 7 sites in United States
- Volunteers
- 246 people
- Sponsor
- Boston Scientific Corporation
Rosacea
A Controlled Study to Assess the Efficacy, Safety and Tolerability of Oral DFD-29 Extended Release Capsules
Clinical assessments of efficacy will be conducted based on Investigator's Global Assessment (IGA, modified scale without erythema), Clinician's Erythema Assessment (CEA), and on inflammatory lesion counts at Weeks 4, 8, 12 and…
- Trial name
- NCT03340961
- Testing
- DFD-29 Extended Release Capsules (40 mg), DFD-29 Extended Release Capsules (20 mg), Oraycea® (doxycycline) Capsules
- Where
- 14 sites in Germany
- Volunteers
- 205 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Vascular Diseases, Peripheral Arterial Disease
Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery
The objective of this post-market clinical follow-up study is to evaluate the clinical outcomes of patients receiving PhotoFix as a patch within a vascular repair or reconstruction procedure.
- Conditions
- Vascular Diseases, Peripheral Arterial Disease, Hemodialysis Access Failure (Disorder), Carotid Artery Diseases
- Trial name
- PHOTO-V (NCT03669042)
- Testing
- PhotoFix
- Where
- 9 sites in United States
- Volunteers
- 94 people
- Sponsor
- Artivion Inc.
Melanoma
Moletest Clinical Study in Scotland
To evaluate an iPad based photoimage analysis system (Moletest) for improving discrimination of benign from malignant suspicious skin lesions or moles.
- Trial name
- NCT02196246
- Where
- United Kingdom
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- Moletest Scotland Ltd
GHK and GHK-Cu Blood Levels
Two-Part Study of the Effects of the X39 Patch on Circulating GHK and GHK-Cu Levels in Healthy Adults
The goal of this clinical trial is to investigate GHK and GHK-Cu blood levels pre- and post-intervention in healthy adults, and to investigate the efficacy of X39 patch on GHK and GHK-Cu blood levels in healthy adults compared to…
- Trial name
- NCT07706361
- Testing
- X39 Patch
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- LifeWave, Inc.
Analgesia and Anti-inflammatory of Osteoarthritis
A Trial of HRF2105 Patch in Relieving Pain of Osteoarthritis
The study is being conducted to evaluate the efficacy, and safety of HRF2105patch in relieving pain of Osteoarthritis.
- Trial name
- NCT06047483
- Testing
- HRF2105 patch, Loxoprofen patch
- Volunteers
- 90 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Stents, Coronary Artery Disease
SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
This study is divided into 5 arms: 1. Randomized Clinical Trial (RCT): Prospective, randomized, active-controlled, single blind, parallel two-arm multi-center clinical trial in the United States (US) comparing XIENCE V®…
- Conditions
- Stents, Coronary Artery Disease, Total Coronary Occlusion, Coronary Artery Restenosis
- Trial name
- NCT00180479
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent, TAXUS® EXPRESS2™ Paclitaxel Eluting Coronary Stent
- Where
- 65 sites in United States
- Volunteers
- 1,002 people
- Sponsor
- Abbott Medical Devices
Non-melanoma Skin Cancer
DERM NMSC Validation Study
This study aims to establish the effectiveness of an Artificial Intelligence (AI) algorithm (DERM) to determine the presence of Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC) and frequently observed benign…
- Trial name
- NCT04116983
- Testing
- Deep Ensemble for the Recognition of Malignancy (DERM)
- Where
- 3 sites in United Kingdom
- Volunteers
- 572 people
- Sponsor
- Skin Analytics Limited
Lung Neoplasms, Pulmonary Neoplasm
ENB Vs. Conventional Bronchoscopy With Fluoroscopy for Safe and Effective Biopsy of Pulmonary Lesions
Evaluate results for participants with lung lesions randomized to either 4D Electromagnetic Navigation Bronchoscopy (4D-ENB) versus Conventional Bronchoscopy with Fluoroscopy for diagnostic biopsy and detection of lung cancer.
- Trial name
- NCT04447482
- Testing
- ENB with image-guided lung biopsy, Conventional Bronchoscopy guided by Fluoroscopy
- Where
- 4 sites in China
- Volunteers
- 212 people
- Sponsor
- Shanghai Youhe Medical Technology Co., Ltd.
Smokers
Nicotine Patch Safety Study
The purpose of this study is to evaluate the safety profile of a repeated application of a new transdermal patch compared to a reference product during 3 weeks, in a large population.
- Trial name
- NCT01655082
- Testing
- V0116 transdermal patch, Nicotine transdermal patch
- Where
- 4 sites in France
- Volunteers
- 160 people
- Sponsor
- Pierre Fabre Medicament
Healthy
A Study to Evaluate Bioequivalence and Adhesion of a Transdermal Contraceptive Patch Manufactured With Newly Sourced Adhesive Components and Currently Marketed EVRA in Healthy Adult Women
The purpose of this study is to determine the bioequivalence of the hormones (ie, norelgestromin [NGMN] and ethinyl estradiol [EE]) from the transdermal contraceptive patch and to evaluate the adhesion of the transdermal…
- Trial name
- NCT03274297
- Testing
- EVRA patch (NGMN+EE) (Treatment A) (Reference), HMW PIB patch (NGMN+EE) (Treatment B) (Test)
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Coronary Artery Disease, Intravascular Lithotripsy
Evaluate the Safety and Efficacy of Intracoronary Lithotripsy Balloon Catheter and Intracoronary Lithotripsy Apparatus
This is a prospective, multi-center, single-group target value clinical trial, which will be carried out in many clinical trial institutions in China.
- Trial name
- NCT05649488
- Testing
- Intracoronary lithotripsy balloon catheter and Intracoronary lithotripsy apparatus, Dragonfly Opstar Imaging Catheter
- Where
- 20 sites in China
- Volunteers
- 184 people
- Sponsor
- Shanghai Bluesail Boyuan Medical Technology Co., Ltd.
Coronary Artery Disease
Study of the Orsiro Drug Eluting Stent System
The purpose of this study is to compare the BIOTRONIK Orsiro Drug Eluting Stent System with the Abbott Xience Prime™ Drug Eluting Stent System with respect to in-stent Late Lumen Loss in a non-inferiority study in de novo…
- Trial name
- BIOFLOW-II (NCT01356888)
- Testing
- Percutaneous Coronary Intervention (Abbott Laboratories - Xience Prime DES), Percutaneous Coronary Intervention (Orsiro DES)
- Where
- 24 sites in Austria, France and 6 more
- Volunteers
- 452 people
- Sponsor
- Biotronik AG
EPIDERMOLYSIS BULLOSA
Trial To Assess Efficacy Of A Chimeric Skin In Patients With Epidermolysys Bullosa
A phase II, comparative, open label, prospective, multicentre clinical trial where each patient will undergo two procedures; implant of a patch of cultured chimeric skin (experimental therapy) in a half of the skin lesion and an…
- Trial name
- TCEB (NCT00987142)
- Testing
- CX501, Occlusive non adherent dressing
- Where
- 2 sites in Spain
- Volunteers
- 12 people
- Sponsor
- Tigenix S.A.U.
Postmenopausal Osteoporosis
A Study to Determine the Patient Preference Between Zosano Pharma Parathyroid Hormone (ZP-PTH) Patch and Forteo Pen
The purpose of this study is to determine which of two delivery methods of Parathyroid Hormone (PTH) is preferred by patients after 14 days of use for each.
- Trial name
- NCT02478879
- Testing
- ZP-PTH, FORTEO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Zosano Pharma Corporation
Blood Pressure
Validation of Cuffless Blood Pressure Measurements Using the Perin Health Patch
This study aims to validate a proprietary cuffless blood pressure algorithm using measurements from a multi-modal chest-worn medical device, the Perin Health Patch (PHP).
- Trial name
- NCT06574113
- Testing
- Perin Health Patch
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Chronic Pain
Efficacy and Safety Study of Fentanyl Transdermal Patch for Treatment of Chronic Pain
The purpose of this study is to confirm effectiveness and safety of fentanyl transdermal patch Durogesic® D-Trans for treatment of chronic pain in participants with chronic non-cancer pain.
- Trial name
- NCT01902524
- Testing
- Fentanyl-TTS
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Janssen Korea, Ltd., Korea
Calcification of Coronary Artery
Coronary Atherectomy System in Patients With Coronary Calcification (CORECT)
This is a prospective and multicenter clinical investigation aiming to evaluate the safety and effectiveness of coronary atherectomy system for the treatment of patients with coronary calcification.
- Trial name
- NCT05447585
- Testing
- Coronary atherectomy system of Shanghai MicroPort Rhythm, Rotablator Rotational Atherectomy System
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Shanghai MicroPort Rhythm MedTech Co., Ltd.
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