Clinical trials: Lesion
Periapical Lesion Healing, Apical Periodontitis
The Effect of Different Intracanal Medicaments on Periapical Lesion Healing
This study is planned to evaluate the effects of two different intracanal medicaments-calcium hydroxide and diclofenac sodium-on periapical healing following endodontic retreatment.
- Trial name
- NCT07237620
- Testing
- Diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Postoperative Pain
Preemptive Use of the Nicotine Patch for Postoperative Pain Relief After Open Abdominal Surgery
The efficacy of a low dose nicotine patch of seven milligrams placed before surgery and its effect on decreasing pain after surgery is the main purpose of the study.
- Trial name
- NCT00790829
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Sessile Serrated Lesion
Polyp Pretreatment Device for SSL Diagnosis
Colorectal cancer (CRC) is the third most common malignancy globally. Sessile serrated lesions (SSLs) account for 15-30% of CRC via the serrated pathway.
- Trial name
- NCT07601230
- Testing
- Polyp Pretreatment Device
- Volunteers
- 1,156 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Malaligned Teeth, Crowding of Teeth
Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
- Trial name
- NCT07753512
- Testing
- Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
Effect of Lidocaine Transdermal Patch as Add-On Therapy in Treatment of Oxaliplatin Induced Peripheral Neuropathy in Colorectal Cancer Patients
Oxaliplatin (OXA) is a third-generation platinum-based chemotherapeutic drug with better efficacy for colorectal carcinoma (CRC).
- Trial name
- NCT05866653
- Testing
- lidocaine transdermal patch
- Where
- Bangladesh
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Carious Lesion
Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions
To evaluate the clinical performance of High-Viscosity Glass Ionomer (EQUIA) versus Silver Diamine Fluoride combined with Potassium Iodide (Riva Star) and Sliver Diamine Fluoride (SDF) under High-Viscosity Glass Ionomer (EQUIA)…
- Trial name
- NCT05485272
- Testing
- Silver Diamine Fluoride combined with Potassium Iodide., Silver Diamine Fluoride., High-Viscosity Glass Ionomer.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Smoking Cessation
Health Literacy and Smoking Cessation in Low-SES Diverse Smokers - Project HALT II
In-Depth Interviews: The goal of this research study is to learn about ways to help people might have trouble understanding health information quit smoking.
- Trial name
- NCT02942212
- Testing
- Questionnaire, In-Depth Interviews, Breath Test
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Epilepsy, Tumor
High-density EEG in Neurological Disorders
The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.
- Conditions
- Epilepsy, Tumor, Healthy
- Trial name
- NCT04266041
- Testing
- High-density electroencephalogram (HD-EEG)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pancreatic Cancer
PANCREATIC DISEASE COHORT A Registry and Biospecimen Bank to Better Understand Pancreatic Disease
The specific aims of this project are to create a registry, as well as a biospecimen bank for individuals with pancreatic disease (e.g.
- Trial name
- NCT01102556
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Caries
Antimicrobial Photodynamic Therapy as an Adjunct for Management of Deep Caries Lesions
Alternatively to conventional treatments, chemo-mechanical caries removal agents can be used. A modality of treatment that has been increasing in dentistry is antimicrobial photodynamic therapy (aPDT).
- Trial name
- NCT05236205
- Testing
- Caries removal with a lowspeed drill, Partial removal of carious tissue with the administration of Papacarie™, Partial removal of carious tissue with the administration of Papacarie™ and application of Bixa Orellana extract (20%)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Chronic Kidney Diseases, Periapical Lesions
Association of Apical Periodontitis With Chronic Kidney Disease
This investigation is aimed to assess the prevalence and severity of apical periodontitis (AP) in different stages of CKD patients and its impact on the systemic (nutritional and inflammatory) markers was compared to healthy…
- Trial name
- NCT05818657
- Testing
- levels of CKD markers, Oral health status, apical periodontitis, systemic inflammatory marker, Oral health status, apical periodontitis
- Where
- India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Non Carious Cervical Lesion
Effect of an Additional Hydrophobic Adhesive Layer Application on the Class V Composite Restorations
In restorative dentistry, to enhance bond strength between dentin and simplified adhesive systems, new materials or applications are constantly being developed all the time.
- Trial name
- NCT05635981
- Testing
- Clearfil Majesty ES-2 Resin Composit Application to Non-carious Cervical Lesions
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma
Near Infrared Technology and Laparoscopic Resection of Pancreatic Lesions: the COLPAN Project
The purpose of this study is to determine whether the use of Near-Infrared Technology can guide the laparoscopic resection of hypervascular neoplasms of the pancreas.
- Conditions
- Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma, Solid Pseudopapillary Tumors of the Pancreas
- Trial name
- NCT02685553
- Testing
- NIR
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
Skin Safety Study to Evaluate the Sensitizing Potential in Healthy Volunteers
This is a single center, randomized, controlled, within subject comparison, multiple dose study to determine the sensitization potential of M518101 on normal skin under occlusive patch condition.
- Trial name
- NCT02256930
- Testing
- M518101, M518101 Vehicle, Sodium lauryl sulfate
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maruho North America Inc.
Hamstring Injury, Muscle Rupture
Effect of NMES+ on Hamstring Lesion (3a/3b)
The goal of this clinical trial is to analyze the effect of the electrical stimulation superimposed onto movement in healthy semi-professional athletes who sustained a type 3a/3b hamstring strain injury.
- Conditions
- Hamstring Injury, Muscle Rupture, Hamstring Sprain
- Trial name
- NCT05786300
- Testing
- NMES+, Rehab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Coronary Artery Disease
Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions
1.) Indigenously developed and designed BioMimeTM is a predictably safe \& efficacious 3rd generation drug eluting stent (DES) with a propensity to minimize vascular injury by use of an intelligent mix of ultra-low strut…
- Trial name
- meriT-1 (NCT01507519)
- Testing
- Sirolimus Eluting Coronary Stent System (Biomime)
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meril Life Sciences Pvt. Ltd.
Meniscus Lesion, Pain (Knee)
The Efficacy of Adductor-Canal-Block (ACB) in Patients After Knee Arthroscopy
The Purpose of this study is to determine whether Adductor-Canal-Block (ACB) is superior to placebo when it comes to analgetic efficacy after Knee-Arthroscopy.
- Conditions
- Meniscus Lesion, Pain (Knee), Diagnostic Knee Artroscopy, Minor Knee Surgery
- Trial name
- NCT01254825
- Testing
- Adductor-Canal-Block, Ropivacain
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
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