Clinical trials: Lesion
Mediastinal ( Chest) Masses, Gastrointestinal Subepithelial Tumors
Role of Endoscopic Ultrasound Elastography in Diagnosis of Gastrointestinal Subepithelial and Mediastinal Lesions
The aim of this study is to evaluate the role of endoscopic ultrasound (EUS) in the diagnosis of mediastinal and gastrointestinal subepithelial lesions.
- Trial name
- NCT07419191
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Anal Cancer, Squamous Intraepithelial Lesions
Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis
This study aims to learn more about anal cancer risk in men who have sex with men (MSM) who are using Pre-Exposure Prophylaxis (PrEP) to prevent HIV.
- Conditions
- Anal Cancer, Squamous Intraepithelial Lesions, HSIL, High Grade Squamous Intraepithelial Lesions, LSIL, Low-Grade Squamous Intraepithelial Lesions
- Trial name
- SCOPE (NCT07029152)
- Testing
- Anal smear, Self-administered questionnaire, EQ-5D-5L questionnaire
- Where
- 8 sites in Belgium
- Volunteers
- 296 people
- Sponsor
- Universitair Ziekenhuis Brussel
Patellar Dislocation, ACL Injury
The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) .
- Conditions
- Patellar Dislocation, ACL Injury, Meniscus Lesion, Trochlear Dysplasia
- Trial name
- FKC (NCT04607538)
- Testing
- No intervention is made
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
White Spot Lesion, Orthodontic Appliance Complication
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
The goal of this randomized clinical trial is to compare the influence of casein phosphopeptide amorphous calcium phosphate (CPP-ACP), CPP-ACP in combination with fluoride (CPP-ACPF), high fluoride concentration, and conventional…
- Trial name
- NCT05710874
- Testing
- CPP-ACP paste, CPP-ACPF paste, 1.25% fluoride gel
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Coronary Chronic Total Occlusions
The Prospective Segeberg Registry for Coronary Chronic Total Occlusions (CTO)
A Prospective Follow-up Assessment in Bad Segeberg with Patients undergoing Recanalization for Coronary Chronic Total Occlusion Lesion/s
- Trial name
- CTO Registry (NCT06957613)
- Testing
- Revascularization/Conservative management
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Segeberger Kliniken GmbH
Breast Diseases
To Evaluate the Efficacy and Safety of LuminoMark Injection in Patients With Nonpalpable Breast Lesions
This study is a multicenter, Open-label, Parallel, Phase 2 Clinical Trial in 6 weeks for screening, once Investigational product injection, Follow up visit.
- Trial name
- NCT03743259
- Testing
- LuminoMark inj. 0.1mL, LuminoMark inj. 0.2mL, Charcotrace Inj.
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Healthy
Effect of External Heat on a Transdermal Granisetron Patch in Pharmacokinetics (PK) of Healthy Subjects
The purpose of this study is to determine the effect of heat applied to a granisetron transdermal patch in healthy subjects.
- Trial name
- NCT01073696
- Testing
- granisetron IV, granisetron patch
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Patellar Tendinopathy
Study Evaluating a Heated Lidocaine and Tetracaine Topical Patch in the Treatment of Patients With Patellar Tendinopathy
The purpose of the study is to explore the potential usefulness of a heated lidocaine 70 mg and tetracaine 70 mg topical patch for the treatment of pain associated with patellar tendinopathy.
- Trial name
- NCT01111773
- Testing
- Heated Lidocaine and Tetracaine Patch
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- ZARS Pharma Inc.
Blood Donation, Blood Transfusion
Donor Lifestyle and Nutritional Status, Blood Component Quality, and Patient Safety (ESENCIA)
The goal of this observational study is to evaluate how blood donors' lifestyle and nutritional status influence the quality of packed red blood cells (pRBCs) during storage and their impact on patient safety in transfused…
- Trial name
- ESENCIA (NCT07558369)
- Where
- Mexico
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Perinatologia
Prevention, Rehabilitation
Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions
The research is about a prospective study conducted in patients suffering from dysphagia and cervical spine disorders and how they are interrelated.
- Trial name
- DysphagCerv (NCT01418105)
- Testing
- Videofluroscopic swallow study (VFSS), cervical spine isometric exercises, Fiberoptic endoscopic esophageal study (FEES)
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Breast Cancer
Using Diagnostic Tools to Stage Breast Cancer
This project is aimed at investigating the relative diagnostic and synergy of four state of the art breast imaging techniques (magnetic resonance imaging (MRI), full-field digital mammography (DMAM), ultrasound, and positron…
- Trial name
- NCT00367666
- Testing
- MRI, Digital Mammography, Ultrasound and Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Pennsylvania
Neuroendocrine Tumors, Autoimmune Pancreatitis
A Real-world Comparison of FNB and FNA in IHC-required Lesions.
Endoscopic ultrasound (EUS)-guided fine needles with side fenestrations are used to collect aspirates for cytology analysis and biopsy samples for histologic analysis.
- Conditions
- Neuroendocrine Tumors, Autoimmune Pancreatitis, Gastrointestinal Stromal Tumors
- Trial name
- NCT05565066
- Testing
- FNB group, FNA group
- Where
- China
- Volunteers
- 439 people
- Sponsor
- Huazhong University of Science and Technology
Basal Cell Carcinoma of Skin, Cutaneous Squamous Cell Carcinoma (CSCC)
Impact of Preoperative High-Frequency Ultrasound Cutaneous Lesion Extent Assessment on Excision Margin Positivity in Head and Neck Skin Cancer, and the Relationship Between Preoperative Assessment Methods, Inadequate Excision Margins, and Tumor Recurrence
Non-melanoma skin cancers (NMSC), particularly basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are the most common malignancies in Caucasians, with the majority of tumors located in the head and neck due…
- Conditions
- Basal Cell Carcinoma of Skin, Cutaneous Squamous Cell Carcinoma (CSCC), Cutaneous Squamous Cell Carcinoma in Situ (CSCCis), Cutaneous Squamous Cell Carcinoma of the Head and Neck
- Trial name
- HFUS-CLEAR (NCT07361666)
- Testing
- High-Frequency Ultrasound, Dermoscopy
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji
Facial Papulopustular Rosacea
A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea
The primary objectives of this study are to determine the efficacy and safety of FMX103 1.5% minocycline foam applied topically once daily for 12 weeks in the treatment of rosacea.
- Trial name
- NCT03142451
- Testing
- FMX103 minocycline foam 1.5%, Vehicle foam
- Where
- 54 sites in United States
- Volunteers
- 751 people
- Sponsor
- Vyne Therapeutics Inc.
Dental Caries in Children
Efficacy of a Chemically Activated Composite Resin Alkasite in Atypical Caries Lesions of Deciduous Teeth
Atypical cavities, which involve more than two surfaces being one of them vestibular or lingual/palatine, are a challenge for restorative dentistry, since the risk of failure of the restorations are related to the number of…
- Trial name
- NCT04195386
- Testing
- Dental Restoration with Chemically activated Composite resin Alkasite, Dental Restoration with Resin-Modified Glass ionomer Cement
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Omental Patch, Laparoscopic Pancreaticoduodenectomy
A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Pancreaticoduodenecotmy(PD) is considered as the standard procedure for peri-amplullary or pancreatic head tumors. Laparoscopic pancreaticoduodenctomy(LPD) has been reported with minimal invasive advantages, such as small…
- Conditions
- Omental Patch, Laparoscopic Pancreaticoduodenectomy, Pancreatic Fistula
- Trial name
- NCT04704882
- Testing
- omental patchwork
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhejiang Provincial People's Hospital
Corneal Toxicity, Ototoxicity
A Comparison of Infection Rates Between Two Surgical Sites
Does the use of chlorhexidine scrub prior to cutaneous surgery on the face increase the chances of toxicity to the eyes or ears? In addition, does the us eof chlorhexidine scrub on the face prior to cutaneous surgery decrease the…
- Conditions
- Corneal Toxicity, Ototoxicity, Surgical Site Infection
- Trial name
- NCT01263262
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dental Diseases
Evaluation of the Initial Color Match of Different Single-shade Composites
The aim of this study was to evaluate the initial colour match of anterior non-carious cervical lesions restored with different single-shade resin composites, namely Omnichroma (Tokuyama) and Charisma Topaz One (Kulzer).
- Trial name
- NCT06473727
- Testing
- Omnichoroma, Charisma Topaz One
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Intracranial Atherosclerosis
An International Registry of the Wingspan™ Stent System for the Treatment of Intracranial Atherosclerotic Stenosis
The IRISS study is designed to collect clinical and angiographic outcomes data when stenting intracranial atherosclerotic lesions using the Wingspan™ Stent System with Gateway™ PTA Balloon Catheter in routine clinical practice.
- Trial name
- IRISS (NCT00929383)
- Testing
- Wingspan Stent System with Gateway PTA Balloon Catheter
- Where
- 19 sites in France, Germany
- Volunteers
- 82 people
- Sponsor
- Stryker Neurovascular
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