Clinical trials: Leukoderma
Upper Cross Syndrome
Comparative Effects of Egoscue and Feldenkrais Exercises on in Upper Cross Syndrome
Upper cross syndrome is a common postural dysfunction that is caused due to alternating tightness and weakness in the opposite muscle groups of the neck, shoulders and upper back which results in abnormal postural deviations.
- Trial name
- NCT07628413
- Testing
- Egoscue exercises, Feldenkrais exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Upper Crossed Syndrome
Cervical Position Sense, Core Stability, and Postural Balance in University Students With Upper Crossed Syndrome
This study aims to investigate the relationship between cervical position sense, core stabilization, and postural balance in university students aged 18-30 years with Upper Crossed Syndrome (UCS).
- Trial name
- NCT07577492
- Testing
- postural and balance assessment battery
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istinye University
Upper Cross Syndrome
Effects of Scapular Stabilization Exercises Combined With Post Facilitation Stretch in Patients With Upper Cross Syndrome: A Randomized Control Trial
Upper Cross Syndrome is characterized by the postural deviation of head , neck , shoulders and altered muscular muscular activation which included weakness of rhomboids , middle and lower trapezius and serratus anterior and…
- Trial name
- NCT06534736
- Testing
- Electrotherapy and physical agents, Post Facilitation Stretch, Scapular Stabilization Exercise
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Vitiligo
Evaluation of Pyroptosis-related Indicators in the Pathogenesis of Vitiligo:Across-sectional Comparative Study
Vitiligo is an acquired pigmentary disorder on skin and/or mucosae, which is characterized by death of melanocytes (MCs), affecting 0.5%-2% of the population worldwide (1).
- Trial name
- NCT06261086
- Testing
- evaluate serum levels pyroptosis-related indicators (GASDM-D, IL 1β & IL-18)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Psoriasis (PsO), Vitiligo Vulgaris
Evaluation of Stigma Toward Patients With Alopecia Areata, Atopic Dermatitis, Vitiligo, and Psoriasis
Primary objective: The primary objective is to evaluate in the general population the difference between emotional reactions associated with facial involvement by four major dermatologic diseases: psoriasis, atopic dermatitis…
- Conditions
- Psoriasis (PsO), Vitiligo Vulgaris, Atopic Dermatitis, Areata Alopecia
- Trial name
- STIGMADERM (NCT06801821)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gingival Hyperpigmentation, Laser Depigmentation
Effect of Topical Argan Oil on Healing After Laser Depigmentation.
Effect of Argan oil vs placebo on healing after laser depigmentation
- Conditions
- Gingival Hyperpigmentation, Laser Depigmentation, Topical Argan Oil, Postoperative Gingival Healing
- Trial name
- NCT07357883
- Testing
- Laser Depigmentation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ghada Adayil
Pigmentation, Gingiva
Post Gingival Depigmentation Assessment: Comparison of Surgical Stripping vs (Er,Cr:YSGG) Laser
The appearance and health of the gingiva significantly contribute to an aesthetically pleasing smile. Pink gingiva indicates healthy gums and is generally preferred over dark or mixed colors.
- Trial name
- NCT06075641
- Testing
- Gingival depigmentation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Vitiligo
5-fluorouracil for Treatment of Stable Vitiligo
Vitiligo, a significant dermatologic challenge affecting 0.5 to 2% of the global population. Despite various existing medical approaches, current vitiligo treatments are still far from optimal.
- Trial name
- NCT06209138
- Testing
- 5 fluorouracil, Saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
UPPER CROSS SYNDROME
Effects of Segmental and Pursed Lip Breathing Exercises on Upper Cross Syndrome
Upper cross syndrome is relative prevalent 67% musculoskeletal disorder among general population due to increased usage of smart gadgets and poor postural habits.
- Trial name
- NCT06303102
- Testing
- Manual PT/ Conventional PT Treatment + Segmental and Pursed Lip Breathing Exercise, Manual PT/Conventional PT Treatment
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Idiopathic Guttate Hypomelanosis
Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study
This pilot study will consist of 10 adult subjects with symmetric idiopathic guttate hypomelanosis on the lower legs. Subjects will be randomized to which extremity (right or left) will be treated.
- Trial name
- NCT01956435
- Testing
- Excimer Light Treatment
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Vitiligo - Evaluation of Methotrexate Iontophoresis and Topical Methotrexate Gel as Localized Treatment Approache
Methotrexate Iontophoresis Versus Methotrexate 1% Gel on Depigmentation in Vitiligo Patients
Vitiligo is a common autoimmune depigmenting disorder characterized by selective destruction of melanocytes. Methotrexate (MTX) has shown potential in stabilizing disease activity and promoting repigmentation; however, systemic…
- Trial name
- NCT07208890
- Testing
- Methotrexate Iontophoresis/a low-intensity electric current
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Visible Light Exposure on Healthy Back Skin
ANTIPIGMENTING OR DEPIMENTING EFFICACY UNDER PART OF VISIBLE LIGHT
The study intends to validate a protocol and define a positive reference to evaluate the efficacy of anti-pigmenting and depigmenting agents under part of visible Light exposures, between 400nm to 450nm.
- Trial name
- ACR_BIOVI_21-0 (NCT06945393)
- Testing
- Cosmetic topical products
- Where
- Romania
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Vitiligo
Human Beta-defensin 1 in Vitiligo
There is a need to know the role of human beta defensin-1 in vitiligo pathogenesis and the probability of finding newer and effective therapy for vitiligo in the future.
- Trial name
- NCT03832751
- Testing
- skin biopsy before and after NB-UVB phototherapy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo Vulgaris
Questionnaire and Laboratory Data on Vitiligo Vulgaris
Vitiligo vulgaris is an autoimmune disorder that causes loss of pigmentation over the skin, hair and mucous membranes (e.g. lips, nose, genitals).
- Trial name
- NCT01206374
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Parkinson Disease, Progression, Disease
Neuromelanin MRI: A Progression Marker in Early PD
Prospective observational study to qualify NM-MRI as progression marker in early Parkinson's.
- Trial name
- InsIghtPD (NCT05631158)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Vitiligo
Role of NGAL in Vitiligo
Role of serum Neutrophil Gelatinase-associated Lipocalin in early detection of cardiovascular risk in patients with Vitiligo
- Trial name
- NCT05290077
- Testing
- NGAL
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Iris Depigmentation
ND-YAG Laser Iris Depigmentation for Cosmoses
Nd-YAG Laser for changing iris coloration by the principle of depigmentation for cosmoses Is that procedure safe or not a prospective study
- Trial name
- NCT06099041
- Testing
- Nd-YAG Laser for iris depigmentation
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sohag University
Upper Crossed Syndrome
The Effects of Dynamic Taping Combined With Corrective Exercises on Cervical Proprioception and Muscle Imbalance in Patients With Upper Crossed Syndrome
Upper Crossed Syndrome (UCS) is a pattern of muscle imbalance that leads to forward head posture, rounded shoulders, or excessive thoracic kyphosis, thereby affecting posture and cervical-shoulder function.
- Trial name
- NCT07182461
- Testing
- Dynamic Tape, Swiss Ball, Dumbbells
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Vitiligo
Molecular Mechanisms of Helium-Neon Laser on Melanocyte Regeneration in Skin Equivalent Vitiligo Model
This current three-year proposal aims to clarify the mechanisms of melanocyte destruction and regeneration in vitiligo lesions using both traditional cell culture and skin equivalent model (organotypic culture).
- Trial name
- NCT00172939
- Testing
- foreskin from healthy adults
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Upper Cross Syndrome
Effect Of PNF Techniques Versus CCEP On Pain, Function and Quality of Life In Patients With Upper Cross Syndrome
The study aims to determine which approach either PNF Techniques or Comprehensive Corrective Exercise Protocol provides better outcomes for pain relief, functional improvement, and quality of life in patients with upper cross…
- Trial name
- NCT07058272
- Testing
- Comprehensive corrective exercise protocol, Proprioceptive Neuromuscular Facilitation (PNF) Techniques
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan