Clinical trials: Lichen Sclerosus et Atrophicus
Vulvar Lichen Sclerosus
StrataMGT for the Treatment of Vulvar Lichen Sclerosus
This study is designed to evaluate the efficacy and safety of StrataMGT for the treatment of vulvar lichen sclerosus.
- Trial name
- NCT06360705
- Testing
- StrataMGT
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Center for Vulvovaginal Disorders
Lichen Sclerosus Lesion
Laser Treatment for Lichen Sclerosus
Fractional ablative laser treatment for Lichen Sclerosus lesion
- Trial name
- NCT06389071
- Testing
- Fractional 2940 nm Laser
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sciton
Herpes Genitalis, Genital Wart
Safety and Efficacy of Laser Therapy in Gynaecology
The aim of this study is to retrospectively evaluate the effectiveness and safety of Er:YAG laser for treatment of different gynecological indication, e.g.
- Conditions
- Herpes Genitalis, Genital Wart, Lichen Sclerosus, Cervical Intraepithelial Neoplasia
- Trial name
- NCT04073082
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Juna d.o.o.
Lichen Sclerosus Lesion
Identification of Genetic Variants Associated With Lichen Sclerosus
Lichen Sclerosus (LS) is a common genital skin condition that severely impacts on daily living. LS occurs worldwide but may be more common in the white population.
- Trial name
- GENITALS (NCT07720830)
- Testing
- No Interventions
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gudula Kirtschig
Lichen Sclerosus Et Atrophicus, Lichen Planus
Laser Therapy in Women With Lichenoid Disorders
Primary aim of the trial is to compare improvement of lichen symptoms according to a composite VAS scale (burning, itching and pain) between women with vulvovaginal laser therapy vs. sham laser therapy at three months.
- Trial name
- Liser (NCT04697563)
- Testing
- Laser
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Lichen Sclerosus
Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life
This observational study aims to evaluate routine treatment outcomes in men with lichen sclerosus (LS), including a long-term follow-up to assess disease progression and histopathological changes.
- Trial name
- NCT06984263
- Testing
- Circumcision
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Västerbotten
Lichen Sclerosus
Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile Microbiome
In genital LSc, three pathological processes are implicated in disease development: inflammation, sclerosis/fibrosis and neoplasia. The role of genital microbiome is still to be investigated and explained.
- Trial name
- NCT05671263
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Region Jönköping County
Lichen Sclerosus
Clobetasol Versus Pimecrolimus for Vulvar Lichen Sclerosus
Lichen sclerosus (LS) is a skin condition of the external genitals (vulva) of women. LS causes vulvar itching, pain, and burning.
- Trial name
- NCT00393263
- Testing
- pimecrolimus and clobetasol, clobetasol 0.05% cream
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Center for Vulvovaginal Disorders
Normal Vulval Skin, Lichen Sclerosus
Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease
Can vibrational spectroscopy be used to accurately assess vulval skin conditions? Vulval skin disorders are common and the diagnosis of these conditions can be difficult.
- Conditions
- Normal Vulval Skin, Lichen Sclerosus, High Grade Dysplasia - Usual Type ('VIN 2-3'), High Grade Dysplasia - Differentiated Type ('VIN 2-3')
- Trial name
- Vulval VS (NCT02223975)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Lichen Sclerosus, Lichen Planus
Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
The objective of the study was to determine sensitivity, specificity and diagnostic accuracy of "Three Rings Vulvoscopy" for detection of vulvar dermatosis using histopathology as the reference standard.
- Conditions
- Lichen Sclerosus, Lichen Planus, Lichen Simplex Chronicus, Vulvodynia
- Trial name
- DATRIV (NCT02732145)
- Testing
- "Three Rings Vulvoscopy" (TRIV), Histopathology
- Where
- Croatia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Ginekološka Poliklinika Dr. Vesna Harni
Quality of Life
Low-Level Laser Therapy: an Efficient Supplement to Treatments of Vulvar Lichen Sclerosus to Improve Quality of Life
Objectives: The aim of this study was to investigate whether Low Level Laser therapy (LLLT) can improve the quality of life in women with Lichen Sclerosus (LS) and insufficient topical treatment.
- Trial name
- NCT05060224
- Testing
- EasyLaser: Low Level Laser therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kolding Sygehus
Vulvar Lichen Sclerosus
Use of Platelet Rich Plasma From Cord Blood vs Placebo in the Treatment of Vulvar Lichen Sclerosus
Vulvar lichen Sclerosus (VLS) is a cutaneous-mucosal dermatosis that causes in the adult female vulvar itching and burning due to scratching abrasions. Dyspareunia is often associated .
- Trial name
- NCT06661382
- Testing
- Infiltrative treatment with CB-PRP
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Bacterial Vaginosis, Candidiasis
Vaginal Ecosystem and Network in the United States Study
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions.
- Conditions
- Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Genitourinary Syndrome of Menopause
- Trial name
- VENUS (NCT06472765)
- Testing
- Vaginal Swab Collection
- Where
- 21 sites in United States, Canada
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Vaginal Biome Science
Urethral Stricture
The Nanofat Regenerative Surgery for Management of Genital Lichen Sclerosus in Male and Female Patients
Regenerative surgery is an emerging multidisciplinary field actually based on derived adipose tissue. Autologous fat grafting was first described by Neuber in 1893 and since then it has developed over the next century.
- Trial name
- LSNanofat (NCT05464290)
- Testing
- NANOfat grafting
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza