Clinical trials: Lifestyle Risk Reduction
HIV Prevention, Pre-exposure Prophylaxis (PrEP)
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
- Conditions
- HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication
- Trial name
- PrEP-3D RCT (NCT05474313)
- Testing
- PrEP-3D package, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Lifestyle Risk Reduction, Type2 Diabetes
Lifestyle Changes Reducing Type 2 Diabetes Risk Among Arab Canadian Muslim Women.
Aim: The purpose was to investigate whether modifiable risk factors for type 2 diabetes can be reduced by an intensive healthy lifestyle intervention designed for Arab Muslim women.
- Trial name
- NCT04708574
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Risk Reduction
Consumer Motivation for Disease Prevention 2 (Clear Labels)
The purpose of this study is to examine (1) how the causal structure of a disease influences people's disease prevention decisions; and (2) how the causal structure of a disease interacts with people's regret anticipation in…
- Trial name
- NCT04228562
- Testing
- non-modifiable factor, induction of anticipated regret
- Where
- Hong Kong
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Satisfaction, Risk Reduction
Electronic Confirmed Versus Conventional Consenting Process: A Randomized Controlled Trial
· The target population for our study is women who present in their last clinic visit before delivery and are scheduled for an elective cesarean section.
- Trial name
- ECCCO (NCT03510260)
- Testing
- Study Group I, Study Group II, Control Group
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pregnancy Early, Outcome, Adverse Birth
Generation R Next - Optimaal Opgroeien
The aim of this randomized controlled trial is to improve birth outcomes and long-term outcomes in mother and child by optimizing lifestyle,nutrition and stress experience in the preconception period and early pregnancy in women…
- Conditions
- Pregnancy Early, Outcome, Adverse Birth, Lifestyle Factors, Preconception Care
- Trial name
- NCT05870878
- Testing
- Standard care, Lifestyle program
- Where
- Netherlands
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Eating Attitudes, Lifestyle Risk Reduction
Eating, Sleep, Attitudes, and Stress Risk in Physical Therapy Students
The goal of this observational study is to assess how eating attitudes, sleep attitudes, and perceived stress contribute to early indicators of cardiovascular risk among undergraduate physical therapy students aged 18-30.
- Conditions
- Eating Attitudes, Lifestyle Risk Reduction, Perceived Stress
- Trial name
- EHSAR-S (NCT07303244)
- Testing
- complete validated questionnaires
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Risk Reduction, Cardiovascular Diseases
Exercise Training & Statins for Cardiovascular Health
Cardiovascular disease (CVD) refers to any condition that affects the heart and/or blood vessels (e.g. heart attack, stroke) and is the leading cause of death and disability worldwide.
- Trial name
- EXSTATIC (NCT05474079)
- Testing
- Moderate intensity exercise training
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardiff Metropolitan University
Risk Behavior, Risk Reduction
An Emotion Regulation Intervention for Early Adolescent Risk Prevention
This study will take a group-based intervention for adolescents that reduced sexual risk behavior and create a computer-based version, which is a format that adolescents like and that is more cost-effective.
- Conditions
- Risk Behavior, Risk Reduction, Emotion Regulation
- Trial name
- NCT03430570
- Testing
- Tablet TRAC Emotion Regulation Intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections, HIV Prevention and Care
HealthMpowerment Korea: Pilot Testing the Cultural Adaptation of a Digital HIV Intervention for Men Who Have Sex With Men in South Korea
This study tests a mobile application (app) designed to support sexual health and prevent human immunodeficiency virus (HIV) among young men in South Korea.
- Conditions
- HIV Infections, HIV Prevention and Care, Risk Reduction Behavior, Digital Health
- Trial name
- HMP Korea (NCT07741123)
- Testing
- Bandi Mobile Application (Full Access), Information-Only Mobile Application (Limited Access)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seul Ki Choi
Child Rearing, Risk Reduction Behavior
Age 9 Follow-up of Preventive Intervention (Denver)
To examine the impact of prenatal and infancy home visiting by paraprofessionals and by nurses from child age 2 through 9.
- Conditions
- Child Rearing, Risk Reduction Behavior, Reproductive Behavior
- Trial name
- DenverY09 (NCT00438594)
- Testing
- home visitation
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases, Motivation
Motivational Interviewing Effect on Reducing Cardiovascular Disease Risk Factors
Aim: The aim of this study is to examine the effect of motivational interviewing-based training program on reducing cardiovascular disease risk factors in adults.
- Conditions
- Cardiovascular Diseases, Motivation, Nurse's Role, Risk Reduction
- Trial name
- NCT06071351
- Testing
- motivational interviewing based training program, Routine practice
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
HIV Infections, Sexual Behavior
HIV and STIs Clinical Study in Germany
The BRAHMS study is a prospective observational cohort study aiming to investigate how often people that are at risk to get infected with HIV contract HIV and how long people stay in the study.
- Conditions
- HIV Infections, Sexual Behavior, Risk Reduction
- Trial name
- NCT03884816
- Testing
- Determine the Incidence and Retention Rate
- Where
- 10 sites in Germany
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Hendrik Streeck
Risk Reduction Behavior, Reduce Risk of Dementia
A Goal-setting With Mentoring Lifestyle Modification Intervention to Reduce Risk of Dementia in Later Life
This is a 5-year project. In the 1st year of this study, a pilot randomized controlled trial evaluating the feasibility and acceptability of a goal-setting behavior change intervention aim at reducing modifiable risk factors for…
- Trial name
- NCT03900156
- Testing
- goal-setting
- Where
- Taiwan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tzu-Ting Huang
Child Rearing, Adolescent Development
Follow-up of Families in Early Preventive Intervention
This project supports the post-third-grade assessment of 693 children and their families who were enrolled in a randomized trial of a program of prenatal and infancy home visitation by nurses that was epidemiologically and…
- Conditions
- Child Rearing, Adolescent Development, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisYear9 (NCT00438516)
- Testing
- nurse home visitation
- Where
- United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cardiovascular Diseases
Cardiovascular Risk Reduction Program Aimed at African American Women (The HHER Lifestyle Program)
Cardiovascular disease (CVD) is a serious health problem among African American women. This study will evaluate a health care center-based program that aims to encourage African American women to eat a low fat diet and increase…
- Trial name
- HHER (NCT00860444)
- Testing
- Basic Educational and Counseling Program, Comprehensive Educational and Counseling Program
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Alzheimer Disease, Cognitive Decline
Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention
Alzheimer's disease (AD) neuropathology is characterized by deposits of insoluble amyloid β-peptide (Aβ) in extracellular plaques and aggregated tau protein, which is found largely in the intracellular neurofibrillary tangles.
- Trial name
- (PENSA) (NCT03978052)
- Testing
- EGCG, Healthy lifestyle recommendations, Multimodal lifestyle intervention
- Where
- 2 sites in Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Risk Reduction
Cultural Competency, Risk Management, and Patient Safety Internet-Based Curriculum for OB/GYN Resident Physicians
Additional educational training lectures were provided to healthcare workers. Outcome measure of cultural competency was completed to assess patient safety, risk management, and cultural competency of healthcare providers in an…
- Trial name
- PROM (NCT02355847)
- Testing
- Lectures
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Brett Worly, MD
Risk Reduction
Improving Caries Risk Using Propolis-containing Versus Fluoride-containing Toothpastes in High Caries Risk Patients
This study will be conducted to evaluate the effect of Propolis-containing toothpaste in comparison to Fluoride-containing Toothpaste by caries risk assessment in high caries risk patients.
- Trial name
- NCT03222960
- Testing
- propolis-containing toothpaste, Fluoride-containing toothpaste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer
Mammogram Mail- and Phone-based Interventions
The project aims to evaluate four different versions and modalities of interventions encouraging mammogram screening among all eligible women due or overdue for screening.
- Trial name
- NCT05853848
- Testing
- Postcard, Letter, Auto-dialer
- Where
- United States
- Volunteers
- 14,386 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic