Clinical trials: Lifestyle Risk Reduction
Dementia Prevention, Subjective Cognitive Impairment
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro).
- Conditions
- Dementia Prevention, Subjective Cognitive Impairment, Mild Cognitive Impairment, Cognitive Change
- Trial name
- BHPROOF (NCT07364019)
- Testing
- Brain Health PRO
- Where
- Canada
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Complications, Sarcoma
Application of a Comprehensive Protocol Aimed at Reducing the Risk of Complications After Surgery for Sarcoma. Interventions Before, During and After Surgery for Known and Presumed Risk Factors Compared to Standard of Care in a Total of 300 Patients.
Sarcoma is a rare malignancy made up by several sub types that can occur throughout the body. Roughly speaking, the division into soft tissue sarcoma (STS) and skeletal sarcoma (SS) can be made.
- Trial name
- NCT06968884
- Testing
- Protocol based, Control (Standard treatment)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Stockholm
Risk Reduction Behavior, Suicide Prevention
SAFEGUARD Level Up Study
This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program.
- Conditions
- Risk Reduction Behavior, Suicide Prevention, Risky Behavior, Mental Health
- Trial name
- NCT07286955
- Testing
- Level Up
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Cardiovascular Disease
"Hjerteloeftet" ("HeartLift"). Interaction For Preventing Cardiovascular Disease
Early interventions to promote physical activity, dietary lifestyle changes and optimal medication for cardiovascular risk factor reduction - 3 years follow-up. A randomized Clinical Trial.
- Trial name
- HeartLift (NCT01741428)
- Testing
- Intervention (INT1)
- Where
- Norway
- Volunteers
- 701 people
- Sponsor
- LHL Helse
Sedentary Behavior, Risk Reduction
Achievement and Adherence to Behavioral Health Goals in the Setting of Patient-Directed Goal Choice
Health care decisions should include patients' health outcome goals and care preferences so as to enable a unified set of individualized patient outcome goals, rather than disparate disease-specific goals that do not reflect…
- Trial name
- NCT04294381
- Testing
- Decision tool
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Fall, Risk Reduction
Prevention Focused Home-Based Physical Therapy Utilizing Community Partnership Referrals
This novel study supports the positive benefits of Home Based Older Persons Upstreaming Physical Therapy (HOP-UP-PT) to older adults identified as "at-risk" by their local senior center after participating in a prevention-focused…
- Trial name
- NCT04814459
- Testing
- HOP-UP-PT Program
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Oakland University
Breast Cancer, Lifestyle Risk Reduction
PIONEER Study of Lifestyle Intervention to Reduced Breast Cancer Risk
A randomised controlled trial in which women discharged from the symptomatic breast clinic, who are above population risk (according to Tyrer Cuzick) will be asked to create lifestyle related goals.
- Trial name
- PIONEER (NCT04574063)
- Testing
- Lifestyle intervention to reduce breast cancer risk
- Where
- United Kingdom
- Volunteers
- 240 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Lifestyle Risk Reduction, Health Behavior
Food Literacy Intervention - is a "Train the Trainer" Approach Feasible and Effective?
Food literacy (FL) is the capability to make healthy food choices in different contexts, settings and situations. Although eating habits are shaped by different circumstances and skills, most nutrition programs focus on nutrition…
- Conditions
- Lifestyle Risk Reduction, Health Behavior, Food Habits
- Trial name
- NCT06258733
- Testing
- Lay-led FL workshops, Expert-led workshops
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Risk Reduction
Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine
This is a randomized, placebo-controlled dose-escalation study. The main purpose of this research is to test the safety and measure the immune response of the trivalent vaccine against invasive Salmonella disease.
- Trial name
- NCT03981952
- Testing
- Trivalent Invasive Salmonella Disease Vaccine (6.25 µg), Trivalent Invasive Salmonella Disease Vaccine (12 µg), Trivalent Invasive Salmonella Disease Vaccine (25 µg)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Community Dwelling, Elderly Adults
Effectiveness of Active Brain Construction Program in Community-Dwelling Older Adults
The urgency of health promotion and dementia prevention is paramount. In 2019, the World Health Organization announced the "Risk reduction of cognitive decline and dementia," which reviewed evidence-based prevention aspects and…
- Conditions
- Community Dwelling, Elderly Adults, Lifestyle Risk Reduction
- Trial name
- NCT07282626
- Testing
- ABC program with coaching, Active comparator (ABC Program)
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Fall, Risk Reduction
Comparison of Three Balance Training Protocols for Individuals Post Stroke
The purpose of this study is to compare conventional balance training to reactive training and to a novel, high intensity, harnessed training program.
- Conditions
- Fall, Risk Reduction, Stroke, Balance
- Trial name
- NCT03757026
- Testing
- Conventional Physical Therapy, Slip Training, Harnessed gaming
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Cleveland State University
Lifestyle Risk Reduction, Adolescent Health
Health Without Barriers/Salud Sin Barreras- Northern Colorado
The overarching goal of this work is to address the limited access to evidence-based health behavior and lifestyle interventions for youth and families most impacted by preventable chronic diseases, including obesity and type 2…
- Conditions
- Lifestyle Risk Reduction, Adolescent Health, Family Health, Cardio-metabolic Health
- Trial name
- HWB/SSB (NCT06822387)
- Testing
- Mindfulness-Based Intervention, Parent Education, Physical Activity
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Health Behavior, Noncommunicable Diseases
The LvL UP Trial: Assessing the Effectiveness of a mHealth Intervention
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06592443
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 1,061 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Metabolic Syndrome, ASCVD
Cardiometabolic Syndrome Response to Therapeutic Lifestyle Changes
Intensive lifestyle intervention has shown to be effective in high risk patient populations and has gathered support from leaders-as outlined in the 2015 consensus paper by the Cardiometabolic Health Alliance.
- Conditions
- Metabolic Syndrome, ASCVD, Lifestyle Risk Reduction
- Trial name
- COSMETIC (NCT04093440)
- Testing
- lifestyle modification
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Holy Cross Hospital, Florida
Adolescent Behavior, Risk Reduction Behavior
HIV/AIDS Orphaned and Vulnerable Children Public Health Evaluation
The PHE study is a two-year longitudinal study evaluating two interventions for reducing depression and HIV risk behaviors among highly vulnerable adolescents in the Eastern Cape of South Africa.
- Conditions
- Adolescent Behavior, Risk Reduction Behavior, Stress, Psychological
- Trial name
- PHE (NCT02386878)
- Testing
- Interpersonal Psychotherapy for Groups (IPTG), Vhutshilo 2
- Volunteers
- 2,302 people
- Sponsor
- Tulane University School of Social Work
Weight Loss, Diabetes Mellitus, Type 2
Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)
The purpose of this study is to examine the effectiveness of a lifestyle intervention designed to reduce weight and diabetes risk in a population of individuals with mental illness who are also taking antipsychotic medications.
- Conditions
- Weight Loss, Diabetes Mellitus, Type 2, Psychotic Disorders
- Trial name
- STRIDE (NCT00790517)
- Testing
- Premier Lifestyle Intervention with DASH Diet
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Opioid Use Disorder, Infectious Disease
Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations
This is a 5-year Hybrid Type 1 Effectiveness-Implementation Randomized Control Trial (RCT) that compares two models of linking and retaining individuals recently released from justice involvement to the continuum of…
- Conditions
- Opioid Use Disorder, Infectious Disease, Risk Reduction Behavior, Substance Use
- Trial name
- ACTION (NCT05286879)
- Testing
- Patient Navigator, Mobile Health Unit
- Where
- 3 sites in United States
- Volunteers
- 601 people
- Sponsor
- Yale University
Asthma
Pilot Study of Changing Exercise and Physical Activity Behavior in Asthma Patients
The objective of this pilot study is to assess the feasibility and the potential differential impact of a novel intervention of induced positive affect and self-affirmation to increase physical activity in asthma patients.
- Trial name
- NCT00227162
- Testing
- Group 1, Group 2, Group 3
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Risk Reduction
Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
ART is given to people living with HIV in order to suppress the virus, resulting in improved health for the individual and decreased transmission of the virus to others. Success of ART is dependent on adherence.
- Trial name
- NCT05333679
- Testing
- UTRA, UTRA feedback
- Where
- South Africa
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Risk Reduction
Assessment of Skill Retention in Clinical Practice
Teaching program population: Participants in Hadassah Ein Kerem ultrasound training day - Anesthesia residents Exclusion criteria: Refusal to participate, insufficient understanding of written English used in the questionnaires…
- Trial name
- NCT02510196
- Testing
- reminder
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization