Clinical trials: Ligament Rupture
ACL Tear
Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation
The aim of this study is to investigate the efficacy of blood flow restriction (BFR) therapy in post-operative rehabilitation following knee arthroscopy for primary ACL reconstruction.
- Trial name
- ACL BFR (NCT05735236)
- Testing
- BFR Cuff
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament Rupture
The Effects of Hormonal Contraceptives on Incidence of ACL Injury Within Menstrual Cycle Phases
The aim of this study is to investigate how hormonal contraceptives affect ACL rupture incidence within menstrual cycle phases. It is thought hormones such as estrogen and progesterone (which fluctuate throughout the normal…
- Trial name
- NCT04986267
- Testing
- ACL Rupture
- Where
- Australia
- Volunteers
- 98 people
- Sponsor
- University of South Australia
Anterior Cruciate Ligament Rupture
Effects of Corporal Visualisation Program of the Static and Dynamic Balance After an Operation of the LCA
The aim of this pilot study is to assess the feasibility of a RCT whose topic would be the effect of a motor imagery program on the postural control in persons who have undergone ACL plasty.
- Trial name
- NCT05081661
- Testing
- Motor Imagery Program
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- HES-SO Valais-Wallis
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Anterior Cruciate Ligament Rupture, Ligament Knee Injury
Association of ALL and ACL Reconstruction Versus Isolated ACL Reconstruction in High-risk Population: a RCT.
Persistent rotational instability after standard ACL reconstruction have been extensively described, and it has been shown to keep straight correlation with worse outcomes post-operatively (Chouliaras 2007, Kocher 2004).
- Trial name
- NCT03229369
- Testing
- Isolated anatomic ACL reconstruction, Combined Anterior Cruciate Ligament and Anterolateral Ligament reconstruction
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Anterior Cruciate Ligament (ACL) Tear
Conventional Follow-up Versus Mobile App For Post-Operative ACL Reconstruction Patients
Background: Telemedicine is increasingly used to overcome distance between patients and physicians. Preliminary studies suggest that mobile app follow-up care for ACL reconstruction patients is feasible, can avert in-person…
- Trial name
- NCT02942940
- Testing
- mobile app, conventional in-person
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto Orthopaedic Sports Medicine
Total Rupture of the Anterior Cruciate Ligament in the Knee
Khalifa Effectiveness Study
The primary hypothesis is that Khalifa's therapy brings additional benefit compared to standard therapy (physiotherapy) for patients with a ruptured anterior cruciate ligament (ACL).
- Trial name
- NCT01762358
- Testing
- Khalifa's therapy, Physiotherapy
- Where
- 4 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Graz
Rupture of Anterior Cruciate Ligament
Comparison of Femoral Tunnel and Clinical Outcome Using Two Anterior Cruciate Ligament Reconstruction Techniques
1. Purpose :To compare of femoral tunnel placement, tunnel geometry and clinical outcome using two anterior cruciate ligament reconstruction techniques ; transportal technique with flexible reamer and single bundle outside in…
- Trial name
- NCT02754674
- Testing
- type of anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Samsung Medical Center
Cruciate Ligament Rupture
Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL…
- Trial name
- NCT02993679
- Testing
- reconstruction of the ACL and anterolateral ligament
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Anterior Cruciate Ligament Rupture
RCT of PEP Program to Reduce ACL Injuries in Female Collegiate Soccer Players
This research study involves implementing and evaluating a physical training program specifically designed to reduce the risk of ligamentous knee injuries in female soccer players by incorporating proven neuromuscular and…
- Trial name
- NCT00140270
- Testing
- PEP program
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-Articular Tenodesis Among High Demand Patients
Anterior Cruciate Ligament Reconstruction with and without Lateral Extra-Articular Tenodesis between high demand patients
- Trial name
- NCT05962580
- Testing
- Isolated anterior cruciate ligament reconstruction with lateral extra articular tenodesis, Isolated anterior cruciate ligament reconstruction only
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Quadriceps Tendon vs Hamstring Tendon Autograft - A Prospective RCT
A prospective randomized controlled trial comparing functional outcomes of arthroscopic anterior cruciate ligament reconstruction using quadriceps tendon autograft versus hamstring tendon autograft at SMS Medical College, Jaipur.
- Trial name
- NCT07470944
- Testing
- Arthroscopic ACL Reconstruction
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sawai Mansingh Medical College
ACL Tear
Safe Return to Play After ACL Reconstruction
Recent studies report that as few as 44% of athletes undergoing ACL reconstruction were able to return to their prior level of competitive level of sports.
- Trial name
- NCT04827264
- Testing
- Safe Return to Play Following ACL Reconstruction Checklist
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Rothman Institute Orthopaedics
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Anterior Cruciate Ligament Injuries Posterior Cruciate Ligament Tear
Interference Screw Mectascrew-B Postmarket Study
An observational prospective study with the aim to assess the clinical outcomes at 1year after surgery for a specific composite IS (Medacta Mectascrew B) in the reconstructive treatment of ruptured ACL or PCL by means of an…
- Trial name
- NCT06166784
- Testing
- Mectascrew B
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- Medacta International SA
Anterior Cruciate Ligament Injury, Ligament Rupture
ACL Versus ALL + ACL Study
The aim of the study is to show a reduction of a re-rupture rate with an ACL (antero crusader ligament) + ALL (anterolateral ligament) combined technique compared to a classical Kenneth-Jones ACL (antero crusader ligament)…
- Trial name
- NCT03740022
- Testing
- ACL plasty, ACL + ALL plasty
- Where
- France
- Volunteers
- 592 people
- Sponsor
- Ascopharm Groupe Novasco
Anterior Cruciate Ligament Rupture
Comparison of Clinical Outcomes Between All-Inside and Complete Tibial Tunnel Techniques in Anterior Cruciate Ligament Reconstruction Among Patients With ACL Ruptures
This study aims to compare the functional outcomes of patients with ACL rupture following ACL reconstruction surgery using hamstring grafts, between the all-inside technique and the complete tibial tunnel technique.
- Trial name
- NCT07023653
- Testing
- All-Inside Techniques, Complete Tibial Tunnel techniques
- Where
- 2 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Anterior Cruciate Ligament Injuries
Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04464330
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Ankle Injuries, Ankle Fractures
Deltoid Ligament Arthroscopic Repair in Ankle Fractures: Case Series
To demonstrate the functional results of patients with ankle fractures operated with arthroscopic deltoid repair.
- Conditions
- Ankle Injuries, Ankle Fractures, Deltoid Ligament; Sprain (Strain) (Ankle), Ligament Rupture
- Trial name
- NCT04473638
- Testing
- Arthroscopic Deltoid Repair
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of São Paulo