Clinical trials: Ligament Rupture
Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears
Added Diagnostic Value of CT Arthrography to MR Arthrography in Wrist Internal Derangement
The wrist is a complex joint made up of small bones, cartilage, and stabilizing ligaments, including the triangular fibrocartilage complex (TFCC) and intrinsic carpal ligaments.
- Conditions
- Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears, Scapholunate Ligament Tears, Lunotriquetral Ligament Tears
- Trial name
- NCT07826208
- Testing
- Combined CT Arthrography and MR Arthrography
- Volunteers
- 60 people
- Sponsor
- Assiut University
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
This observational study aims to evaluate the long-term recovery and clinical outcomes of patients undergoing minimally invasive (arthroscopic) surgeries for sports-related shoulder and knee injuries.
- Conditions
- Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries, Tibial Meniscus Injuries, Shoulder Dislocation or Subluxation
- Trial name
- SK-COHORT (NCT07501013)
- Testing
- Standard of Care Shoulder Arthroscopy, Standard of Care Knee Arthroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anterior Cruciate Ligament Rupture
Comparison of Remnant Preserving Versus Remnant Resecting Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament injury is very common knee injury. Especially Anterior cruciate ligament complete rupture leads to knee joint instability and degenerative change of the knee.
- Trial name
- NCT02555917
- Testing
- anterior cruciate ligament reconstruction
- Volunteers
- 40 people
- Sponsor
- The Catholic University of Korea
Knee Ligament Injury, PCL - Posterior Cruciate Ligament Rupture
Evaluation of Clinical and Radiographic Outcomes of Surgically Treated Multiligamentous Knee Injuries
Multiligament knee injuries are typically caused by high-energy mechanisms and are classified according to the number of ligaments involved using Schenk's classification (Knee Dislocation) into KD 1, KD 2, KD 3, and KD 4.
- Conditions
- Knee Ligament Injury, PCL - Posterior Cruciate Ligament Rupture, PROMs
- Trial name
- MULTI-LIG (NCT06522659)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Scapholunate Dissociation, Scapholunate Ligament Rupture
Scapholunate Ligament Reconstruction Using Modified Flexor Carpi Radialis Tenodesis
Retrospective study of patients who underwent a modified flexor carpi radialis (FCR) tenodesis for scapholunate ligament injury at Waldfriede Hospital during the period 2016-2026.
- Trial name
- NCT07667114
- Testing
- modified flexor carpi radialis tenodesis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Waldfriede Hospital
ACL Tear, Opioid Misuse
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR)…
- Conditions
- ACL Tear, Opioid Misuse, Pain, Anxiety
- Trial name
- NCT06274008
- Testing
- Exparel
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
ACL Injury
Rehabilitation Treatment of Anterior Cruciate Ligament Rupture
The purpose with this present study is to investigate the effect og a non-surgical regime in patients with an Anterior Cruciate ligament injury.
- Trial name
- NCT04408885
- Testing
- Rehabilitation
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital
Knee Ligament; Laxity
Accuracy and Stability of a New Automatic Knee Arthrometer in Diagnosing ACL Rupture
We introduced an automatic knee arthrometer (AKA) and aimed to evaluate the repeatability and effectiveness thereof in diagnosing ACL rupture compared with the KT-2000.
- Trial name
- NCT04956315
- Testing
- Side-to-side difference (reproducibility), Side-to-side difference (availability), Side-to-side difference (Accuracy)
- Where
- China
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
ACL Tear
Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL…
- Trial name
- NCT05532189
- Testing
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Anterior Cruciate Ligament Tear
IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament…
- Trial name
- NCT03983941
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sujana Dontukurthy
Anterior Cruciate Ligament Rupture
The Effects of Remnant-Preserving Anterior Cruciate Ligament Reconstruction on Proprioception and Functionality
Anterior cruciate ligament (ACL) reconstruction is a frequently performed surgical procedure to stabilize the knee joint biomechanically.
- Trial name
- NCT05057442
- Testing
- Proprioception assessment, functionality assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Acibadem University
ACL Tears
The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic ACL Reconstruction
Study Objective: The study aims to determine if tranexamic acid (TXA) is as effective as a tourniquet in improving visual clarity during arthroscopic ACL reconstruction surgery.
- Trial name
- NCT06781021
- Testing
- Tourniquet, TXA
- Where
- Jamaica
- Volunteers
- 60 people
- Sponsor
- The University of The West Indies
Anterior Cruciate Ligament Tear
Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months…
- Trial name
- IMAGERIEMOTR (NCT07210489)
- Testing
- Reconstructive surgery after anterior cruciate ligament rupture, sessions from a physical therapist
- Where
- France
- Volunteers
- 70 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Injuries
Prolonged Preoperative Rehabilitation in ACL Rupture.
Rupture of the anterior cruciate ligament is a serious and common injury. In young athletes, surgical reconstruction of the anterior cruciate ligament by autograft with hamstrings or patellar ligament is widely used.
- Trial name
- ISO-LCA-PREOP (NCT04888052)
- Testing
- Acute ACL injury
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Ligament Rupture
Informing the Patient on the Type of Management, Surgical or Functional, After Rupture of the Anterior Cruciate Ligament
The purpose of the study is to evaluate the proportion of patients after rupture of the anterior cruciate ligament (ACL) of the knee, who will have functional or surgical management (PEC) in 1st intention, after having received…
- Trial name
- INFO-LCA (NCT05585528)
- Testing
- Functional or surgical management in 1st intention
- Where
- France
- Volunteers
- 106 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Rupture
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different, 2.
- Trial name
- NCT06769711
- Testing
- Surgical procedure using Peroneus Longus for ACL reconstruction., Surgical procedure using Hamstring tendons for ACL reconstruction.
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Karadeniz Technical University
Rupture of Anterior Cruciate Ligament
Multicenter ACL Revision Study (MARS)
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL)…
- Trial name
- MARS (NCT00625885)
- Where
- 49 sites in United States, Canada
- Volunteers
- 1,234 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
ACL Tear
Psychological Factors Influencing the Patient-reported and Functional Outcome of ACL Reconstruction and Their Sex-specific Differences
Psychological parameters among patients undergoing ACL reconstruction and their impact on the patient-reported and functional outcome of reconstruction will be prospectively evaluated
- Trial name
- NCT06156501
- Testing
- ACL Reconstruction
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Complete Tear, Knee, Anterior Cruciate Ligament
Gait Rehabilitation Following an Anterior Cruciate Ligament Reconstruction
A randomized control trial where subjects following an anterior cruciate ligament reconstruction will be randomized to either a control group who will receive the normal rehabilitation or an experimental group who will perform a…
- Trial name
- NCT02930239
- Testing
- Gait rehabilitating with reduced bodyweight, Standardized rehabilitation following an anterior cruciate ligament reconstruction at Linkoping University Hospital
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University