Clinical trials: Ligament Rupture
ACL Injury, ACL Tear
Comparison of Six-Month Functional Outcomes Following Anterior Cruciate Ligament (ACL) Reconstruction Using Peroneus Longus Tendon Grafts With Adjunctive Secretome Injection Versus Without Secretome Injection
Anterior cruciate ligament (ACL) reconstruction is commonly performed to restore knee stability after ACL injury; however, graft healing remains a critical determinant of successful outcomes.
- Trial name
- Secretome ACL (NCT07723625)
- Testing
- Secretome
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- PT. Prodia Stem Cell Indonesia
Anterior Cruciate Ligament Rupture
Reconstruction of the ACL With QT Graft With Bone Plug vs BPTB
Background: Anterior cruciate ligament (ACL) injury is one of the most common orthopedic injuries worldwide. Currently, the use of the bone patellar tendon bone graft (BPTB) technique is considered the gold standard.
- Trial name
- NCT06189573
- Testing
- Anterior cruciate ligament Reconstruction with autologous quadriceps tendon graft, Anterior cruciate ligament Reconstruction with autologous bone patellar tendon bone graft
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Rehabilitacion
ACL - Anterior Cruciate Ligament Rupture
SharkScrew ACL RCT
This prospective, randomized controlled trial will compare three tibial interference screw types used for graft fixation during primary anterior cruciate ligament (ACL) reconstruction: a polyetheretherketone (PEEK) screw, a…
- Trial name
- NCT07830953
- Testing
- ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Austrian Workers Compensation Board Styria
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear
Active Noise-Cancelling Headphones With Closed-Loop Communication During Arthroscopic ACL Reconstruction
Operating room noise may interfere with communication, concentration, and surgical workflow. Active noise-cancelling (ANC) headphones can reduce background auditory distractions; however, their potential benefit during surgery…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Injury
- Trial name
- ANC-ACL-2026 (NCT07589582)
- Testing
- Active Noise-Cancelling Headphones With Closed-Loop Communication, Standard Operating Room Communication
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
ACL - Anterior Cruciate Ligament Rupture, ACL
Use of an Osteoconductive Scaffold in ACL-Reconstruction
Primary objective of the study is to evaluate efficacy of the surgical technique for ACL reconstruction using an osteoconductive scaffold, enlaced into the hamstring tendon autograft, compared to the traditional technique.
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL, ACL Injury
- Trial name
- ACLROCS (NCT03462823)
- Testing
- Osteoconductive scaffold-hamstring tendon composite repair, Hamstring tendon-only repair
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- Sandro Fucentese
Anterior Cruciate Ligament Injury
Acute Anterior Cruciate Ligament Rupture; RecOnsTruction Or Repair?
To investigate the hypothesis that suture repair of a ruptured vkb, combined with a dynamic intraligamentary stabilization and microfracture of the femoral notch, results in at least equal effectiveness compared with an ACL…
- Trial name
- ROTOR (NCT02310854)
- Testing
- ACL Repair, ACL reconstruction
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Anterior Cruciate Ligament Tear, Posterior Cruciate Ligament Tear
Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries
Background: The anterior cruciate ligament(ACL) , one of the major ligaments in the knee joint which connects the posterior aspect of the lateral femoral condyle to the anterior intercondylar area of the tibia.
- Trial name
- NCT06233305
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament (ACL) Revision Surgery: French National Study
This is a national multicentric study led by the French Arthroscopy Society (SFA) evaluating clinical practice in anterior cruciate ligament (ACL) revision surgery (epidemiological data, morphological data, operative data…
- Trial name
- NCT06379308
- Testing
- questionaries, datas of medical record
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Hamstring Versus Quadriceps
The use of hamstrings and quadriceps autografts as an alternative option for reconstruction of the anterior cruciate ligament has good clinical results: however, both techniques have not been compared among them, which is why…
- Trial name
- NCT04137250
- Testing
- Hamstring, Quadriceps tendon
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Rupture of Anterior Cruciate Ligament
Stability of the Knee Joint After Single and Double Bundle Anterior Cruciate Ligament Reconstruction
The purpose of this prospective study is to evaluate the influence of both bundles on the knee stability - anterior-posterior translation, internal and external rotations after the double-bundle reconstruction of Anterior…
- Trial name
- NCT01391650
- Testing
- 'biomechanic of the knee'
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Ankle (Ligaments); Instability (Old Injury), Ankle Ligament Rupture
French Ankle Ligament Surgery Cohort Study
This 20-year cohort study foolows patients after ankle ligament reconstruction surgery to evaluate re-rupture rates, long term functional outcomes, return to sport rates ans complications? The goal is to provide insights into the…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Ligament Rupture, Ankle Instability, Syndesmotic Injury
- Trial name
- AnkleCDS (NCT07188363)
- Testing
- Ligament reconstruction
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Chirurgie Du Sport
ACL Tear
Comparison Effectiveness Analysis Between ACL Reconstruction and Rehabilitation in Peripheral and Main Capital in Indonesia
The study was a prospective observational analysis of cases with complete ACL tears. A study was conducted between February 2021 to December 2024.
- Trial name
- Cetjap-Asin (NCT04748328)
- Testing
- ACL Reconstruction surgery and Rehabilitation Treatment
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Riau
Anterior Cruciate Ligament (ACL) Tears
Early Treatment for Acute ACL Tear
This research study is the first of its kind and will allow health care professionals and researchers to answer many questions about the reasons why anterior cruciate ligament (ACL) injury leads to knee pain and disability and…
- Trial name
- AAA (NCT01692756)
- Testing
- Kenalog
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Cale Jacobs
Scapholunate Ligament Tear
In Vivo Kinematics of Scapolunate Interosseous Ligament Injuries
The investigators hypothesize that there is no relationship between in vivo kinematic abnormalities and patient-rated outcomes for scapholunate interosseous ligament injuries (SLIL) The secondary null hypotheses are that: There…
- Trial name
- NCT03017040
- Testing
- CT scan, Fluoroscopy Scan
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Anterior Cruciate Ligament Rupture
A Clinical Trial of the Round-tunnel and Flat-tunnel Technique of ACL Reconstruction
This study intends to perform round-tunnel and flat-tunnel ACL reconstruction technique in 144 patients, and compare the clinical outcomes of the two surgical procedures through follow-up.
- Trial name
- NCT04953676
- Testing
- round tunnel technique, flat tunnel technique
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture, Tendon Injuries
Shear-Wave Elastography of Regenerated Hamstring Tendons After ACL Reconstruction (SWE-ACL)
Anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendon grafts is a commonly performed procedure. Although the semitendinosus and gracilis tendons demonstrate regeneration at the donor site, the…
- Conditions
- Anterior Cruciate Ligament Rupture, Tendon Injuries, Muscle Weakness
- Trial name
- SWE-ACL (NCT07555782)
- Testing
- Shear-Wave Elastography Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anterior Cruciate Ligament Rupture
Absorbable Interface Screw Clinical Trial
Validation of the safety and efficacy of absorbable interface screws for clinical use
- Trial name
- NCT05431790
- Testing
- Absorbable interface screws manufactured by Natong Biotechnology, Absorbable interface screws manufactured by INION.
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma.
Arthrogenic Muscle Inhibition (AMI) is one of the classic complications occurring in the aftermath of knee trauma; AMI is grossly defined as a lack of extension due to quadriceps inhibition and hamstring contracture.
- Trial name
- CAMIK (NCT03950024)
- Testing
- functional brain MRI
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Toulouse
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Anterior Cruciate Ligament Rupture
The Clinical Efficacy of Anterolateral Complex Augmentation in Patients With ACL Rupture Combined With Excessive Internal Tibial Rotation Subluxation: A Bidirectional Cohort Study
This project aims to establish a high-quality, large-scale, single-center bidirectional cohort study to evaluate the postoperative clinical efficacy of ACLR combined with ALC augmentation in a specific high-risk…
- Trial name
- NCT06961292
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Peking University Third Hospital