Clinical trials: Limb Pain
Chronic Pain, Limb Fracture
Chronic Pain Predictors in Major Trauma
The goal of this observational study is to learn about who is at risk of developing chronic pain in a major trauma population with at least one limb fracture.
- Trial name
- COPE: MT (NCT07237152)
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- University of Nottingham
Limbs Arthrosis, Non Arthrosic Limbs Arthralgia
Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
At Saint-Antoine's hospital, in CETD a multidisciplinary team takes care of patients with chronic pain. Free-drug techniques are available to reduce their consumption of analgesics.
- Conditions
- Limbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back Pain
- Trial name
- HYPTENS (NCT01944150)
- Testing
- Transcutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Pain, Fracture
Single Shot Versus OnQ Pump in Extremity Fractures
Peripheral nerve blocks have been well studied in the literature with generally good results for controlling post operative pain following orthopaedic surgery. Regional anesthesia has many benefits.
- Trial name
- NCT02280291
- Testing
- Ankle SSB, Ankle OnQ, DR SSB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Patellofemoral Pain Syndrome
Kinematics of Lower Limb, Pain and Function of the Women With Patellofemoral Pain Syndrome
Assess pain, function, trunk and lower limbs kinematic during functional tasks after hip muscle strengthening versus hip muscle strengthening and sensory motor training in lower limbs.
- Trial name
- NCT01804608
- Testing
- Strength, Sensorimotor
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Nove de Julho
Muscle Injury, Lower Limb Injury
Effects of ART® on Lower Limb Myofascial Pain and Function
This is a feasibility study to determine if the investigators can conduct a clinical trial with a sham and control soft tissue treatment.
- Trial name
- NCT04535635
- Testing
- Active Release Techniques®
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Canadian Memorial Chiropractic College
Amputation, Phantom Limb Pain
Prevention of Phantom Limb and Stump Pain Using Ambulatory Continuous Peripheral Nerve Blocks: A Pilot Study
The purpose of this research study is to determine if putting local anesthetic through one or two percutaneous catheters placed next to the nerves that go to an amputated limb will decrease long-term pain in the amputated limb.
- Conditions
- Amputation, Phantom Limb Pain, Stump Pain
- Trial name
- NCT00771862
- Testing
- perineural ropivicaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Diego
Chronic Pain in the Extremities, Chronic Abdominal Pain
Screening for Fabry Disease in a Pediatric Population at Risk
The purpose of this study is to assess the frequency of Fabry disease in children with chronic abdominal pain or chronic pain in the extremities
- Conditions
- Chronic Pain in the Extremities, Chronic Abdominal Pain, Fabry Disease
- Trial name
- NCT02152189
- Testing
- Screening for Fabry disease
- Where
- Germany
- Volunteers
- 1,422 people
- Sponsor
- University Hospital Heidelberg
Chronic Pain
Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain
The purpose of this study is to evaluate the clinical utility of neurophysiological measurements of ECAP-controlled closed-loop SCS (i.e., neural panel metrics) to guide treatment of chronic pain of the trunk and/or limbs.
- Trial name
- Neural Panel (NCT06229470)
- Testing
- Evoke Spinal Cord Stimulation (SCS) System
- Where
- 25 sites in United States
- Volunteers
- 250 people
- Sponsor
- Saluda Medical Pty Ltd
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Hyperhidrosis
Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating
The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo.
- Trial name
- NCT01671800
- Testing
- Botulinum Type B
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
The Effect of Preoperative Administration of Oral Tizanidine, Post Operative Pain
The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality
The majority of lower limb fractures treated with surgery often leading to significant morbidity and mortality. Despite improvements in perioperative care, about 20% suffer from severe postoperative complications.
- Trial name
- Tizanidine (NCT07800364)
- Testing
- Tizanidine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Amputation, Traumatic, Phantom Sensation
Investigating The Effect of Phantom Sensation on Gait in Individuals With Unilateral Below-Knee Amputation
Amputation is a problem that can be encountered for many reasons, can cause functional disability in varying severities and puts a multifaceted financial burden on individuals, society, and states.
- Trial name
- NCT05177341
- Testing
- Determining Preferred Walking Speed
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Elbow Fracture
Acute Effects of Dual Task on Physical Function in Patients With Elbow Joint Fracture
Elbow injuries account for up to 15% of emergency consultations. The complexity of this joint and the subtle imaging findings present even in severe injuries make diagnosis difficult and can delay treatment, causing pain and…
- Trial name
- ACEDTELBOW (NCT05391139)
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Valencia
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Fascicular Block, Motor Activity
The Effects of Different Clonidine Concentrations on Axillary Brachial Plexus Block With 1,5% Lidocaine
The purpose of this study is to determine whether different clonidine concentration on axillary brachial plexus block with 1,5% lidocaine for upper limb surgery may influence the sensory and motor block onset time and duration…
- Conditions
- Fascicular Block, Motor Activity, Pain, Postoperative, Latency Period
- Trial name
- NCT01620112
- Testing
- high Clonidine concentration, low clonidine concentration, Lidocaine
- Volunteers
- 60 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Breast Cancer Surgery, Transcutaneous Electric Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Breast Surgery
The aim of this randomized controlled trial was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on postoperative pain, lymphedema development, shoulder range of motion, and quality of life in women…
- Trial name
- NCT06973265
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Seda Akutay
Peripheral Arterial Disease, Critical Limb Ischemia
ACPs in Severe PAD/CLI by Direct Intramuscular Injection
Study title: A Study of Blood-Borne Autologous Angiogenic Cell Precursors Therapy in Patients with Critical Limb Ischemia ( ACPs-CLI ) Principle Investigator: Assoc.Prof. Pramook Mutirangura,M.D.
- Trial name
- NCT00523731
- Testing
- Angiogenic Cell Precursors (ACPs) or Vescell TM
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- TheraVitae Ltd.
Critical Limb Ischemia, Ischemia
VEGF Gene Transfer for Critical Limb Ischemia
The purpose of this gene therapy study is to evaluate the safety and efficacy of intramuscular gene transfer using Vascular Endothelial Growth Factor (VEGF) or placebo in patients with moderate to high-risk Critical Limb Ischemia…
- Conditions
- Critical Limb Ischemia, Ischemia, Leg Ulcer
- Trial name
- NCT00304837
- Testing
- pVGI.1 (VEGF-2)
- Where
- 3 sites in United States
- Sponsor
- Losordo, Douglas, M.D.
Low Back Pain
Role of Steroids and 10% Hypertonic Sodium Chloride in Adhesiolysis in Post Lumbar Surgery Syndrome Patients
To evaluate the effectiveness of steroids and/or 10% hypertonic sodium chloride in percutaneous adhesiolysis in managing chronic low back and/or lower extremity pain in patients with post lumbar surgery syndrome.
- Trial name
- NCT01053572
- Testing
- Adhesiolysis
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah