Clinical trials: Limbal Stem Cell Deficiency
Glaucoma, Ocular Hypertension
Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma
Background Intact corneal epithelium is important for the defense on the ocular surface, and the function of limbal stem cells is crucial to maintain its integrity.
- Conditions
- Glaucoma, Ocular Hypertension, Limbal Stem Cell Deficiency
- Trial name
- NCT07119580
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rare Diseases, Aniridia
Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies
The cross-sectional observational clinical study related to rare eye diseases is a multi-center study in which the hypothesis is that neurokinin 1 receptor and/or substance P expression is increased in REDs associated with…
- Conditions
- Rare Diseases, Aniridia, Neurotrophic Keratopathy, Limbal Stem Cell Deficiency
- Trial name
- NCT06412718
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Limbal Stem-cell Deficiency
Multiple Noninvasive Examination Modality to Evaluate the Severity of Ocular Surface Disorders
Here the investigators proposed this study to collect cases of different etiologies of ocular surface diseases. With at least one of these four non-invasive examination modalities, the investigators aim to analyze and compare the…
- Trial name
- NCT03594370
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Limbal Stem Cell Deficiency
Cultivated Autologous Oral Mucosal Epithelial Transplantation
Earlier protocol for cultivated oral mucosal epithelial transplantation (COMET) requires trypsin/EDTA to isolate epithelial cells from tissue, and uses murine 3T3 cells as feeder cells, which results in biosafety concern.
- Trial name
- NCT03943797
- Testing
- Cultivated oral mucosal epithelial cell transplantation
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital