Clinical trials: Lipid
Dry Eye, Tear Film
Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome
With the potential to address evaporative dry eye, Liposic and Tears Naturale Forte have been developed in which phospholipid liposomes are delivered to the tear film via the surface of the closed eyelid.
- Conditions
- Dry Eye, Tear Film, Lipid Layer, Liposic
- Trial name
- NCT03211351
- Testing
- Liposic, Tears Naturale Forte
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Huaxia Eye Hospital Group
Hypertriglyceridemia, Obesity
Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women
Hypertriglyceridemia is a serious condition in the Mexican population and it is considered a major risk factor for cardiovascular disease.
- Trial name
- NCT04966494
- Testing
- BOSB
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Queretaro
Overweight, Hypertriglyceridemic Waist
Effect of Arginine Supplementation in the Metabolic Syndrome
The purpose of this study is to determine whether oral supplementation with one form of arginine improves vascular endothelial function in healthy subjects with risk factors associated with the metabolic syndrome
- Trial name
- NCT02354794
- Testing
- One form of arginine
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Genetic Differences of Lipid Metabolism/Healthy Subjects
Botanical Oils Study to Determine Genetic Differences in the Way Your Body Processes Fats in Edible Oils
A randomized, controlled, cross-over clinical trial of borage oil vs soybean oil to determine whether the metabolism and/or impact of medium chain-polyunsaturated fatty acids (MC-PUFAs) in botanical oil supplements are changed in…
- Trial name
- NCT02337231
- Testing
- soybean oil and borage oil
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Respiratory Syncytial Virus Immunization
Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older
Brief Summary of Stage 1: The purpose of Stage 1 (Phase I/IIa) was to assess the safety and immunogenicity of a single intramuscular (IM) injection of 3 dose-levels of an Respiratory Syncytial Virus (RSV) vaccine candidate…
- Trial name
- NCT05639894
- Testing
- RSV vaccine candidate
- Where
- 33 sites in United States, Australia and 1 more
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Body Fat Disorder
Impact of Oral Dyglomera™ on Body Fat and Blood Lipids of Overweight and Obese Adults
The extract of Dichrostachys glomerata (DyglomeraTM), has been reported to be effective in weight reduction in obese patients with metabolic syndrome.
- Trial name
- Dyglomera (NCT05483192)
- Testing
- Oral Dyglomera
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gateway Health Alliance
Lipoprotein Lipase Deficiency
Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency
Lipoprotein lipase (LPL) is an enzyme that plays an important role in removing triglycerides (TG) (molecules that transport dietary fat) from the blood.
- Trial name
- AGL12 (NCT04227678)
- Testing
- Heparin, liquid meal
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Stress, Psychological, Physiological
Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
The purpose of this study is to determine whether inversions (specific yoga postures in which the heart is higher than the head) and other dynamic and static yoga postures affect heart rate variability, oxygen uptake, blood…
- Trial name
- NCT01305096
- Testing
- Yoga intervention
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Chronic Metabolic Disorder, Lipid Metabolism Disorders
Randomized Clinical Trial of HMR(Home Meal Replacement)-Type Omega-3-balanced-diet
Investigate whether HMR(Home meal replacement)-type omega-3-balanced-diet can improve clinical laboratory values related to chronic metabolic diseases through reducing lipids and chronic inflammation, and can prevent muscle loss.
- Conditions
- Chronic Metabolic Disorder, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT04552574
- Testing
- HMR(Home meal replacement)-type omega-3-balanced diet
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Chungbuk National University Hospital
Sports Physical Therapy
Evaluation of the Efficacy of Panax Ginseng on Lipid Metabolism in Men and the Relationship With Sports Practice.
Panax Ginseng (P ginseng), C.A. Meyer, Red, Chinese or Korean ginseng is a plant from eastern Asia and is one of the most widely used herbal products in the world.
- Trial name
- GinsengRun (NCT03888196)
- Testing
- Panax Ginseng Supplementation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Healthy Subjects
Effects of Exercise on Fructose Metabolism
A high fructose diet increases fasting and post-prandial triglyceride (TG) concentrations in sedentary healthy human subjects.These effects may be secondary to fructose-induced hepatic de novo lipogenesis.
- Trial name
- FruEx2 (NCT01866215)
- Testing
- exercise, fructose, glucose
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Osteoporosis, Cardiovascular Diseases
Effect of Soy Bread on Markers of Bone Metabolism and Cardiovascular Disease
A study was designed with two specific aims: (1) to assess the effect of soy bread, compared with wheat bread, on markers of bone metabolism and cardiovascular health, and (2) to evaluate whether soy bread consumption affects the…
- Trial name
- NCT00366860
- Testing
- Soy bread
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Sedentary Lifestyle
Exercise After Clinically Significant Weight Loss
The Prescribed Exercise to Reduce Recidivism After Weight Loss Pilot (PREVAIL-P) study will evaluate the effect of aerobic exercise training amount on weight maintenance following clinically significant weight loss.
- Conditions
- Obesity, Sedentary Lifestyle, Insulin Resistance
- Trial name
- PREVAIL-P (NCT03685123)
- Testing
- Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Diamond Blackfan Anemia, Dyskeratosis Congenita
Cancer in Inherited Bone Marrow Failure Syndromes
Background: A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these disorders.
- Conditions
- Diamond Blackfan Anemia, Dyskeratosis Congenita, Fanconi Anemia, Shwachman Diamond Syndrome
- Trial name
- NCT00027274
- Where
- 2 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Metabolic Syndrome
The Effects of Nanomicelles Curcumin on Glycemic Control, Serum Lipid Profile ,Blood Pressure and Anthropometric Measurements in Patients With Metabolic Syndrome
Metabolic syndrome is a condition which is recognized by abdominal obesity, dyslipidemia, hyperglycemia, and hypertension. Curcumin has beneficial effects such as antioxidant and anti-inflammatory effects.
- Trial name
- NCT03534024
- Testing
- nanomicielle curcumin
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Obesity, Hypertriglyceridemia
Effects of Omega-3 Fatty Acids on Markers of Inflammation
The major purpose of this study is to examine the effect of two sources of dietary omega-3 fatty acids, each given at two doses, on potential health benefits related to cardiovascular disease prevention.
- Conditions
- Obesity, Hypertriglyceridemia, Insulin Resistance, Hypertension
- Trial name
- NCT01129050
- Testing
- Fish Oil, Flaxseed Oil
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypercholesterolemia, Cardiovascular Risk Factor
Effects of 6 Weeks TOTUM-070 on Lipid Metabolism and Cardiovascular Health in Individuals at Increased Cardio-metabolic Risk
This clinical study aims to assess the efficacy of 6 weeks 2.5g dose of TOTUM-070, a mix of 5 plant extracts, on lipid metabolism and cardiovascular health in individuals at increased cardio-metabolic risk.
- Conditions
- Hypercholesterolemia, Cardiovascular Risk Factor, Dyslipidemias, Atherosclerosis
- Trial name
- OLALIP (NCT05594979)
- Testing
- TOTUM-070
- Where
- France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Visual Acuity
Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
This is a single visit, randomized, double masked, bilateral, non-dispensing, 2×2 crossover study to assess visual acuity.
- Trial name
- NCT06131476
- Testing
- Blink® Tears eye drops, Investigational lipid eye drops
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
LDL Cholesterol, Triglycerides
Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels.
The purpose of this study is to assess the safety and efficacy of a natural health product among participants with elevated LDL cholesterol and triglyceride levels.
- Trial name
- NCT01028274
- Testing
- Investigational Product 1, Investigational Product 2
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nordic Pharma, USA
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