Clinical trials: Liver Transplant Recipients
Liver Transplant; Complications
Lung Ultrasound as a Point of Care Test for Living Donor Liver Transplant Recipients.
Liver transplant is now a standard treatment for end-stage liver disease patients. Pulmonary complications are common in the perioperative period and are associated with adverse outcomes.
- Trial name
- NCT04413695
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Hiv
HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients
The primary objective of this study is to determine if an HIV-infected donor liver (HIVD+) transplant is safe with regards to major transplant-related and HIV-related complications
- Trial name
- NCT03734393
- Testing
- HIVD+/R+
- Where
- 26 sites in United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Liver Transplant; Complications, Perioperative/Postoperative Complications
Effect Of Delta Sodium on the Postoperative Outcomes in Liver Transplant Recipients
We analyzed the association of delta sodium levels with their effect on post liver transplant outcomes in consecutive patients undergoing liver transplantation.
- Conditions
- Liver Transplant; Complications, Perioperative/Postoperative Complications, Electrolyte Disturbance
- Trial name
- SOLT (NCT04112004)
- Testing
- Collecting sodium reports and outcome measures
- Where
- India
- Volunteers
- 342 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Liver Transplantation, Carbapenem-Resistant Enterobacteriaceae Colonization
Impact of a Risk Stratification Tool on the Outcome of Liver Transplant Recipients Colonized With Carbapenem Resistant Enterobacteriaceae: an Observational Study
Although CRE infection after OLT have a dramatic impact on patient survival and several implementations have been proposed (i.e.
- Trial name
- NCT05594901
- Testing
- Application of a prognostic score
- Where
- 6 sites in Brazil, Italy and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Bologna
Liver Failure
SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation
Standard anesthetic management of liver transplantation patients includes a general anesthetic using multiple drugs, including the neuromuscular relaxant rocuronium.
- Trial name
- NCT01404793
- Testing
- Rocuronium
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University Health Network, Toronto
Cervical Cancer, Hpv
Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?
The purpose of the study is to understand if children with liver and kidney transplants develop the antibodies from the Gardasil vaccine.
- Conditions
- Cervical Cancer, Hpv, Warts
- Trial name
- NCT01101750
- Testing
- Quadrivalent HPV for types 6, 11, 16 and 18
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Non-alcoholic Fatty Liver Disease
Non-invasive Diagnosis of Non-alcoholic Steatohepatitis in Liver Transplant Recipients
The purpose of this study is is to use non-invasive diagnostic tests, Fibroscan and a simple blood test, to diagnose NASH in patients who undergo liver transplantation.
- Trial name
- NCT03128918
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Liver Transplantation, Fatigue
Home-Based Exercise Education in Liver Transplant Recipients
Liver transplant recipients often experience reduced physical activity levels, fatigue, and increased caregiver burden after transplantation. Structured home-based exercise education may help improve these outcomes.
- Conditions
- Liver Transplantation, Fatigue, Physical Inactivity
- Trial name
- Liv (Liver) (NCT07417423)
- Testing
- Home-Based Exercise Education, Brochure-Based Exercise Education (Experimental)
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Hasan Kalyoncu University
Liver Transplantation
Enteric Coated Myfortic for Liver Transplant Recipients
The purpose of this study is to replace the mycophenolate mofetil (Cellcept) which is our usual therapy after liver transplantation with sodium mycophenolic acid (Myfortic®) and to find out the effect this change may have on the…
- Trial name
- NCT00167492
- Testing
- Myfortic
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Liver Transplant Recipients
Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.
Both isoflurane and propofol are being used to give anaesthesia for living donor liver transplant in our institute. Propofol when compared to isoflurane has advantages like early awakening from anaesthesia, reduced nausea…
- Trial name
- NCT06418893
- Testing
- Target control infusion propofol, Inhalational isoflurane
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Liver Transplant, Kidney Transplant
A 5 Year Follow-up of Patients Who Were Previously Enrolled Into an Advagraf Trial Following a Liver or Kidney Transplant
The purpose of this study is to evaluate the impact of Advagraf, prolonged-release, once daily tacrolimus formulation, on long-term graft survival in kidney and liver allograft recipients.
- Trial name
- ADDRESS (NCT02057484)
- Testing
- Tacrolimus
- Where
- 145 sites in Austria, Belarus and 22 more
- Volunteers
- 2,300 people
- Sponsor
- Astellas Pharma Europe Ltd.
Cytomegalovirus Infection
A Study of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients
The purpose of this study is to assess the effect of pre-transplant mRNA-1647 on post-transplant cytomegalovirus (CMV) virologic outcomes, anti-CMV antiviral use, and clinical outcomes in CMV-seropositive and CMV-seronegative…
- Trial name
- NCT06133010
- Testing
- mRNA-1647
- Sponsor
- ModernaTX, Inc.
Pediatric Liver Transplanted Recipients, Healthy Donors
Living Donor Liver Transplantation in Children
Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.
- Trial name
- NCT02124382
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Liver Transplantation
To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients
This study's objective is to evaluate the incidence rate of acute rejection reactions after 24 weeks treatment with ADVAGRAF® following 3 months treatment with tacrolimus in new liver transplant recipients.
- Trial name
- Assign (NCT04761731)
- Testing
- ADVAGRAF®
- Volunteers
- 31 people
- Sponsor
- Linical Korea
Complication of Transplanted Liver
Genetic Predisposition-Chronic Nephrotoxicity From CI-Liver Transplant Recipients-Potential Correlation-Urinary Biomarkers
The purpose of this study is to determine the relationship between genomic variants of components of the renin-angiotensin system and the development of kidney problems due to Calcineurin-inhibitors post liver transplant.Also the…
- Trial name
- NCT00857844
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Northwestern University
Kidney Transplant, Liver Transplant
A Cohort Study of Operationally Tolerant Allograft Recipients
Antirejection medicines, also known as immunosuppressive drugs, are prescribed to organ transplant recipients to prevent their bodies from rejecting the new organ.
- Trial name
- ALLTOL (NCT02743793)
- Testing
- Blood Draw
- Where
- 5 sites in United States
- Volunteers
- 41 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Post Liver Transplant Infection
Effect of Preoperative Vitamin D Supplementation in Liver Transplant Recipients With Vitamin D Deficiency on Post Transplant Outcomes
Liver transplantation (LT) remains the ultimate option to cure intractable end stage liver disease. Vitamin D deficiency is very common in these subsets of patients.
- Trial name
- NCT06736093
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Solid Organ Transplant Recipient (Liver, Kidney, Heart), Rheumatologic Disorder
Immunogenicity of Fluzone High Dose in Immunocompromised Children and Young Adults
The purpose of this study is to determine whether Fluzone High Dose increases the immune response to the influenza antigens contained in the vaccine compared to standard-dose Fluzone in immunocompromised children and young…
- Conditions
- Solid Organ Transplant Recipient (Liver, Kidney, Heart), Rheumatologic Disorder, Human Immunodeficiency Virus (HIV), Bone Marrow Transplant (BMT)
- Trial name
- NCT01685372
- Testing
- Fluzone High Dose, Fluzone
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Colorado, Denver
Measles
Induction of Immunity Against Measles in Pediatric Liver Transplant Recipients
Measles is a vaccine-preventable disease, which can be life-threatening in immunosuppressed children. Currently, measles vaccine is not recommended in pediatric orthotopic liver transplant recipients, because it is a…
- Trial name
- MMRinOLT (NCT01770119)
- Testing
- MMR vaccination
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Klara M. Pósfay Barbe
Hepatitis C, Kidney Transplant; Complications
A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients
This study is being done to determine the effectiveness of using a combination of two different drugs in preventing the transmission of HCV from a HCV positive donor to a HCV negative solid organ recipient.
- Conditions
- Hepatitis C, Kidney Transplant; Complications, Heart Transplant Infection
- Trial name
- NCT04508907
- Testing
- Mavyret
- Where
- United States
- Volunteers
- 227 people
- Sponsor
- Mayo Clinic