Clinical trials: Lobectomy
Lung Cancer (NSCLC)
Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection.
- Trial name
- NCT07841249
- Testing
- Lobectomy, Sublobar Resection
- Where
- China
- Volunteers
- 604 people
- Sponsor
- Tongji Hospital
Pneumothorax, Pleural Effusion
16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy
The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or…
- Trial name
- ChestDrain (NCT06958848)
- Testing
- 16 F chest tube, 24 F chest tube, Early removal
- Where
- Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Basel, Switzerland
Anterior Temporal Epilepsy, Anterior Temporal Lobectomy
Anterior Temporal Epilepsy Neuropsychological Assessment of Faces
The purpose is to evaluate neuropsychological effects of anterior temporal epilepsy in face perception by comparison of performances of epileptic patients and control individuals, sex-, age- and socio-educational level-matched.
- Conditions
- Anterior Temporal Epilepsy, Anterior Temporal Lobectomy, Face Perception
- Trial name
- ATENA-F (NCT02888925)
- Testing
- Mooney test, Benton Face Recognition test, Face inversion effect test
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Caregiver, Lobectomy Patient
Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
This trial studies whether a telephone-based physical activity intervention before and after lung cancer surgery can be provided to older patients and their caregivers.
- Conditions
- Caregiver, Lobectomy Patient, Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma
- Trial name
- NCT04085081
- Testing
- E-mail, Exercise Intervention, Quality-of-Life Assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Lung Cancer, Thoracic Surgery, Video-Assisted
3D Lung Reconstructions Using Open-source Software for Lung Cancer Surgery
Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration.
- Conditions
- Lung Cancer, Thoracic Surgery, Video-Assisted, Lobectomy, Segmentectomy
- Trial name
- 3D-LUNG (NCT06132607)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Erik de Loos
Anesthesia, Conduction, Pain Management
The Effects of Ultrasound-guided Serratus Plane Block During Video-assisted Thoracoscopic Lobectomy
This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
- Trial name
- NCT03718377
- Testing
- Serratus plane block, General anesthesia only
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Thoracoscopic Lobectomy
Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management
Phase Ⅱ, randomized, double-blind, comparator-controlled study to evaluate the efficacy, safety and pharmacokinetics of single injection intercostal nerve block with HR18034 for postoperative pain management compared with…
- Trial name
- NCT05744674
- Testing
- HR18034, Ropivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Lung Cancer
Pulmonary Artery Sealing Using the HARMONIC ACE+ Shears(HS) for VATS Lobectomy
VATS anatomical lung resection provides an effective minimally invasive treatment strategy for stage I and II lung cancer. VATS lobectomy is associated with significantly less postoperative atrial fibrillation, blood transfusion…
- Trial name
- NCT01975623
- Testing
- HARMONIC ACE®+ Shears (HS)
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Carcinoma, Non-Small-Cell Lung
Effect of Different Anesthetics on the Change of Alarmins in Lung Cancer Patients Receiving Pulmonary Lobectomy
This study aim to observe and compare the change of alarmins such as high mobility group nucleosome-binding protein-1 (HMGN1), high mobility group proteins b1 (HMGb1), Interleukin (IL)-33 and their soluble receptors including…
- Trial name
- NCT02916147
- Testing
- Sevoflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Stage IA Non-small Cell Lung Cancer
Optimal Extent of Pulmonary Resection in Clinical Stage IA Non-Small Cell Lung Cancer
The investigatros hypothesized that selection of surgical procedure according to the pre-defined institutional decision-making algorithm will not compromise the treatment outcomes including overall survival and disease-free…
- Trial name
- OREX-IA (NCT03066297)
- Testing
- Extent of pulmonary resection
- Where
- South Korea
- Volunteers
- 1,018 people
- Sponsor
- Samsung Medical Center
Chest Tubes, Pneumonectomy
Safety and Feasibility of the Application of Thoracic Puncture Tube After Pulmonary Lobectomy
There have been several reports on the feasibility of a no-drain policy after pneumonectomy, but the policy is not widely accepted because silent massive hemorrhage, delayed air leaks, and chylothorax would always be major…
- Conditions
- Chest Tubes, Pneumonectomy, Minimally Invasive Surgery
- Trial name
- NCT04718272
- Testing
- thoracic drainage management
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University Union Hospital
Lung Cancer
Treatment of Early Stage Lung Cancer by VATS Versus OPEN Lobectomy
In patients with early stage lung cancer surgical lobectomy is the treatment of choice. A resection by Video-assisted Thoracic Surgery (VATS) is probably superior to an open procedure by thoracotomy for patients with early stage…
- Trial name
- SCOPE (NCT01933828)
- Testing
- OPEN lobectomy, VATS lobectomy, ROBOT-assisted lobectomy
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Atrial Fibrillation
Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery
This study intends to explore a new therapy to reduce the incidence of atrial fibrillation in thoracic patient who receive video-assisted thoracoscopic lobectomy .The results of the study are to assess the effects of this new…
- Trial name
- NCT03919786
- Testing
- topical local anesthesia of pulmonary vein combined with vagus nerve block
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Han Yuan
Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy
Right Ventricular Afterload Indices in Lung Surgery
Lung cancer is a leading cause of cancer death in Scotland and the UK. Surgery, typically using a keyhole approach, provides the best chance of cure.
- Conditions
- Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy, One Lung Ventillation (OLV)
- Trial name
- RAILS (NCT07812207)
- Testing
- Contrast cardiac magnetic resonance imaging, Right heart catheterisation, Perioperative plasma sampling
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Lung Neoplasms
Uniportal Versus Triportal Thoracoscopic Lobectomy and Sublobectomy for Early Stage Lung Cancer
Lung cancer is one of the most common cancers in the world. At present, surgical resection is still the standard treatment for early stage lung cancer.
- Trial name
- NCT02933294
- Testing
- Triportal pulmonary resection surgery, Uniportal pulmonary resection surgery
- Where
- 4 sites in China
- Volunteers
- 356 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Surgery for Primary Lung Cancer
Non-Invasive Ventilation Preoperative Lung Resection Surgery
Surgical treatment is the standard treatment for localized forms of lung cancer non-small cell. It allows a 5-year survival exceeding 50% for complete resection of the tumor.
- Trial name
- préOVNI (NCT01685580)
- Testing
- Manufacturer (VPAP ST)
- Where
- 15 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Lung Neoplasm, Adult ALL
LUS to Assess Lung Injury After Lung Lobectomy
The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.
- Conditions
- Lung Neoplasm, Adult ALL, Lung Injury, Lung Inflammation
- Trial name
- OPEN THORUS (NCT04755478)
- Testing
- Thoracotomy, VATS
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital General Universitario de Valencia
Lung Cancer
Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation
This is a randomized placebo-controlled trial studying the effects of intraoperative continuous airway pressure (CPAP) on the inflammatory response of the lung with cancer undergoing lobectomy.
- Trial name
- NCT01368601
- Testing
- CPAP (Continuous airway pressure)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Parc de Salut Mar
Lung Cancer
Ultrasonic Energy for Pulmonary Artery Branch Sealing During VATS Lobectomy
This research program consists of a prospective, multi-institutional Phase 2 trial and an economic cost-effectiveness analysis for the use of ACE+7 in VATS lobectomy/segmentectomy compared to traditional techniques.
- Trial name
- VATS PA-ACE (NCT02719717)
- Testing
- Harmonic Ace+7
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)